ID A0A0R3PMK0_ANGCS Unreviewed; 203 AA.
AC A0A0R3PMK0;
DT 20-JAN-2016, integrated into UniProtKB/TrEMBL.
DT 20-JAN-2016, sequence version 1.
DT 28-JAN-2026, entry version 35.
DE RecName: Full=Mitotic spindle assembly checkpoint protein MAD2A {ECO:0000256|ARBA:ARBA00068928};
DE AltName: Full=Mitotic arrest deficient 2-like protein 1 {ECO:0000256|ARBA:ARBA00076594};
GN ORFNames=ACOC_LOCUS6129 {ECO:0000313|EMBL:VDM57714.1};
OS Angiostrongylus costaricensis (Nematode worm).
OC Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida;
OC Rhabditina; Rhabditomorpha; Strongyloidea; Metastrongylidae;
OC Angiostrongylus.
OX NCBI_TaxID=334426 {ECO:0000313|WBParaSite:ACOC_0000612801-mRNA-1};
RN [1] {ECO:0000313|WBParaSite:ACOC_0000612801-mRNA-1}
RP IDENTIFICATION.
RG WormBaseParasite;
RL Submitted (FEB-2017) to UniProtKB.
RN [2] {ECO:0000313|EMBL:VDM57714.1, ECO:0000313|Proteomes:UP000267027}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Costa Rica {ECO:0000313|EMBL:VDM57714.1,
RC ECO:0000313|Proteomes:UP000267027};
RG Pathogen Informatics;
RL Submitted (NOV-2018) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000256|ARBA:ARBA00004123}.
CC -!- SIMILARITY: Belongs to the MAD2 family.
CC {ECO:0000256|ARBA:ARBA00010348}.
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DR EMBL; UYYA01003922; VDM57714.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A0R3PMK0; -.
DR STRING; 334426.A0A0R3PMK0; -.
DR WBParaSite; ACOC_0000612801-mRNA-1; ACOC_0000612801-mRNA-1; ACOC_0000612801.
DR OMA; WQFDVEI; -.
DR OrthoDB; 1806at2759; -.
DR Proteomes; UP000267027; Unassembled WGS sequence.
DR GO; GO:0000776; C:kinetochore; IEA:TreeGrafter.
DR GO; GO:1990728; C:mitotic spindle assembly checkpoint MAD1-MAD2 complex; IEA:UniProtKB-ARBA.
DR GO; GO:0005654; C:nucleoplasm; IEA:TreeGrafter.
DR GO; GO:0051301; P:cell division; IEA:UniProtKB-KW.
DR GO; GO:0007094; P:mitotic spindle assembly checkpoint signaling; IEA:TreeGrafter.
DR FunFam; 3.30.900.10:FF:000002; Mitotic spindle assembly checkpoint protein MAD2A; 1.
DR Gene3D; 3.30.900.10; HORMA domain; 1.
DR InterPro; IPR003511; HORMA_dom.
DR InterPro; IPR036570; HORMA_dom_sf.
DR InterPro; IPR045091; Mad2-like.
DR PANTHER; PTHR11842; MITOTIC SPINDLE ASSEMBLY CHECKPOINT PROTEIN MAD2; 1.
DR PANTHER; PTHR11842:SF11; MITOTIC SPINDLE ASSEMBLY CHECKPOINT PROTEIN MAD2A; 1.
DR Pfam; PF02301; HORMA; 1.
DR SUPFAM; SSF56019; The spindle assembly checkpoint protein mad2; 1.
DR PROSITE; PS50815; HORMA; 1.
PE 3: Inferred from homology;
KW Cell cycle {ECO:0000256|ARBA:ARBA00023306};
KW Cell division {ECO:0000256|ARBA:ARBA00022618};
KW Mitosis {ECO:0000256|ARBA:ARBA00022776};
KW Nucleus {ECO:0000256|ARBA:ARBA00023242};
KW Reference proteome {ECO:0000313|Proteomes:UP000267027}.
FT DOMAIN 13..197
FT /note="HORMA"
FT /evidence="ECO:0000259|PROSITE:PS50815"
SQ SEQUENCE 203 AA; 23617 MW; B1D6B3D2B9FC9604 CRC64;
MTDTKIKGNI SLKGSAQLVQ EFFHYGINSI LYQRGLYPGD TFRREKKYGL TLLVTNDPKL
QQFLNPLLKQ VEFWLSKRKL KRLVVVISEI KTREVMERWQ FDIQTEDMNE EGENSTRQKD
EKKIKQEIAD VIRQITASVT FLPLLEEPCS FDVLIYTGKE TEAPEDWVES SACLIKNCEQ
VQLRSFSTAV HNVNTNVQYK GDF
//
