ID   A0A0U5G2X6_ASPCI        Unreviewed;       532 AA.
AC   A0A0U5G2X6;
DT   16-MAR-2016, integrated into UniProtKB/TrEMBL.
DT   16-MAR-2016, sequence version 1.
DT   02-APR-2025, entry version 33.
DE   RecName: Full=RBR-type E3 ubiquitin transferase {ECO:0000256|ARBA:ARBA00012251};
DE            EC=2.3.2.31 {ECO:0000256|ARBA:ARBA00012251};
GN   ORFNames=ASPCAL06363 {ECO:0000313|EMBL:CEL05245.1};
OS   Aspergillus calidoustus.
OC   Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Eurotiomycetes;
OC   Eurotiomycetidae; Eurotiales; Aspergillaceae; Aspergillus;
OC   Aspergillus subgen. Nidulantes.
OX   NCBI_TaxID=454130 {ECO:0000313|EMBL:CEL05245.1, ECO:0000313|Proteomes:UP000054771};
RN   [1] {ECO:0000313|Proteomes:UP000054771}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=SF006504 {ECO:0000313|Proteomes:UP000054771};
RX   PubMed=26966204; DOI=10.1128/genomea.00102-16;
RA   Horn F., Linde J., Mattern D.J., Walther G., Guthke R., Scherlach K.,
RA   Martin K., Brakhage A.A., Petzke L., Valiante V.;
RT   "Draft genome sequences of fungus Aspergillus calidoustus.";
RL   Genome Announc. 4:0-0(2016).
CC   -!- CATALYTIC ACTIVITY:
CC       Reaction=[E2 ubiquitin-conjugating enzyme]-S-ubiquitinyl-L-cysteine +
CC         [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-
CC         cysteine + [acceptor protein]-N(6)-ubiquitinyl-L-lysine.;
CC         EC=2.3.2.31; Evidence={ECO:0000256|ARBA:ARBA00001798};
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DR   EMBL; CDMC01000005; CEL05245.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A0U5G2X6; -.
DR   STRING; 454130.A0A0U5G2X6; -.
DR   OMA; YHEVERH; -.
DR   OrthoDB; 10009520at2759; -.
DR   Proteomes; UP000054771; Unassembled WGS sequence.
DR   GO; GO:0004842; F:ubiquitin-protein transferase activity; IEA:InterPro.
DR   GO; GO:0008270; F:zinc ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0016567; P:protein ubiquitination; IEA:InterPro.
DR   CDD; cd22584; Rcat_RBR_unk; 1.
DR   Gene3D; 1.20.120.1750; -; 1.
DR   Gene3D; 3.30.40.10; Zinc/RING finger domain, C3HC4 (zinc finger); 1.
DR   InterPro; IPR031127; E3_UB_ligase_RBR.
DR   InterPro; IPR002867; IBR_dom.
DR   InterPro; IPR044066; TRIAD_supradom.
DR   InterPro; IPR013083; Znf_RING/FYVE/PHD.
DR   InterPro; IPR017907; Znf_RING_CS.
DR   PANTHER; PTHR11685; RBR FAMILY RING FINGER AND IBR DOMAIN-CONTAINING; 1.
DR   Pfam; PF01485; IBR; 2.
DR   SMART; SM00647; IBR; 2.
DR   SUPFAM; SSF57850; RING/U-box; 2.
DR   PROSITE; PS51873; TRIAD; 1.
DR   PROSITE; PS00518; ZF_RING_1; 1.
PE   4: Predicted;
KW   Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW   Reference proteome {ECO:0000313|Proteomes:UP000054771};
KW   Repeat {ECO:0000256|ARBA:ARBA00022737};
KW   Transferase {ECO:0000256|ARBA:ARBA00022679};
KW   Ubl conjugation pathway {ECO:0000256|ARBA:ARBA00022786};
KW   Zinc {ECO:0000256|ARBA:ARBA00022833};
KW   Zinc-finger {ECO:0000256|ARBA:ARBA00022771}.
FT   DOMAIN          334..532
FT                   /note="RING-type"
FT                   /evidence="ECO:0000259|PROSITE:PS51873"
FT   REGION          102..153
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          171..220
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        104..118
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        127..137
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   532 AA;  60208 MW;  4FABCD12A9223928 CRC64;
     MSNASDPRQS ELDDEILALI QQVEEIELYR GNQEGVGRLD KPPDNELAVL VFLDEVNSAL
     GLASSRKPAQ KATYATRLNF GHVRMEPGGG PDKAGEYVLA TKEPSAHDRD GTERKGKAEP
     SMTYTGRWED NRERDGPRFI GTAEKKSRRQ QYHEVERHPI EAIYYQRGQL SQHQFEPSPP
     IVSDEASRRP AGKIPSQGQL RPHQFDPTPA RPIHEGLGQW DDPVQLQGQF RTHHLEPARP
     RHIDEAFGRP GGTIPPQGQL MPQDFGLTPT RRTGFEQMLD PIQLREQRRA HQLESTPARY
     NHEALDRAAL LSRRHLTLAG GVIEYSQMEA TGSDHDDCIA CYSSDLHPSD MRRLGCGHSY
     CFECLKRLFA SSVKTESLFP PRCCRIPIPL LVVEAKMSQH EIARCKMAEV EFGTPWPDRT
     YCSNRNCNSF IPRSNITKTQ ARCSSCKTTT CTKCKNGYHS RESCSPDSDL QETLELSARE
     GWKRCASCGS MVERIEGCLH MTCRCKAQFC YNCGGKWRAC QCEREQALFR YL
//