ID A0A0V0SM73_9BILA Unreviewed; 625 AA.
AC A0A0V0SM73;
DT 16-MAR-2016, integrated into UniProtKB/TrEMBL.
DT 16-MAR-2016, sequence version 1.
DT 05-FEB-2025, entry version 20.
DE SubName: Full=Phosphatidylinositol 3-kinase regulatory subunit gamma {ECO:0000313|EMBL:KRX27981.1};
GN Name=Pik3r3 {ECO:0000313|EMBL:KRX27981.1};
GN ORFNames=T07_7279 {ECO:0000313|EMBL:KRX27981.1};
OS Trichinella nelsoni.
OC Eukaryota; Metazoa; Ecdysozoa; Nematoda; Enoplea; Dorylaimia;
OC Trichinellida; Trichinellidae; Trichinella.
OX NCBI_TaxID=6336 {ECO:0000313|EMBL:KRX27981.1, ECO:0000313|Proteomes:UP000054630};
RN [1] {ECO:0000313|EMBL:KRX27981.1, ECO:0000313|Proteomes:UP000054630}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ISS37 {ECO:0000313|EMBL:KRX27981.1};
RA Korhonen P.K., Edoardo P., Giuseppe L.R., Gasser R.B.;
RT "Evolution of Trichinella species and genotypes.";
RL Submitted (JAN-2015) to the EMBL/GenBank/DDBJ databases.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:KRX27981.1}.
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DR EMBL; JYDL01000001; KRX27981.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A0V0SM73; -.
DR STRING; 6336.A0A0V0SM73; -.
DR OrthoDB; 3175255at2759; -.
DR Proteomes; UP000054630; Unassembled WGS sequence.
DR GO; GO:0005942; C:phosphatidylinositol 3-kinase complex; IEA:TreeGrafter.
DR GO; GO:0046935; F:1-phosphatidylinositol-3-kinase regulator activity; IEA:TreeGrafter.
DR GO; GO:0016301; F:kinase activity; IEA:UniProtKB-KW.
DR GO; GO:0008286; P:insulin receptor signaling pathway; IEA:TreeGrafter.
DR GO; GO:0046854; P:phosphatidylinositol phosphate biosynthetic process; IEA:TreeGrafter.
DR CDD; cd12923; iSH2_PI3K_IA_R; 1.
DR CDD; cd09942; SH2_nSH2_p85_like; 1.
DR Gene3D; 1.10.287.1490; -; 1.
DR Gene3D; 3.30.505.10; SH2 domain; 2.
DR InterPro; IPR032498; PI3K_P85_iSH2.
DR InterPro; IPR035022; PI3kinase_P85_nSH2.
DR InterPro; IPR000980; SH2.
DR InterPro; IPR036860; SH2_dom_sf.
DR PANTHER; PTHR10155; PHOSPHATIDYLINOSITOL 3-KINASE REGULATORY SUBUNIT; 1.
DR PANTHER; PTHR10155:SF10; PI3K21B, ISOFORM B; 1.
DR Pfam; PF16454; PI3K_P85_iSH2; 1.
DR Pfam; PF00017; SH2; 2.
DR PRINTS; PR00678; PI3KINASEP85.
DR PRINTS; PR00401; SH2DOMAIN.
DR SMART; SM00252; SH2; 2.
DR SUPFAM; SSF55550; SH2 domain; 2.
DR PROSITE; PS50001; SH2; 2.
PE 4: Predicted;
KW Coiled coil {ECO:0000256|SAM:Coils}; Kinase {ECO:0000313|EMBL:KRX27981.1};
KW Reference proteome {ECO:0000313|Proteomes:UP000054630};
KW SH2 domain {ECO:0000256|ARBA:ARBA00022999, ECO:0000256|PROSITE-
KW ProRule:PRU00191}; Transferase {ECO:0000313|EMBL:KRX27981.1}.
FT DOMAIN 219..314
FT /note="SH2"
FT /evidence="ECO:0000259|PROSITE:PS50001"
FT DOMAIN 518..613
FT /note="SH2"
FT /evidence="ECO:0000259|PROSITE:PS50001"
FT COILED 410..437
FT /evidence="ECO:0000256|SAM:Coils"
SQ SEQUENCE 625 AA; 72345 MW; 8DFFD07FF68C53D8 CRC64;
MSHKKKHESP CTLGNVFDDI VSAFFQYYHL FIYKLIITFC TDAAQKEVVK NRAILKMFCK
DAFSFAKWKV DDLRANIKLL KSRLTYLTLK LYRFRIRCSK FCCVCRTLLW VVSSCLTSVA
VQWTCLSVFS CQFEFAVNFA INQTFCLIGE YWRFMVEPSS STSEQCKSII PLGAFDDLTE
EQLVDLCKQI DEEENVERVV TEPVPKPTDD KQQSAHPAWY WGDASRDEVN VQMRDQPDGT
FCVRNSSTVG DYTLTVRTGG CNKMIRIYQR DGRFGFSPET SMQFTSLEDF VKHYSSNSLS
AYNRNLNLVL QNPLSRRMRF TSINTDQLVK ISRSLCKQYK LKSNRYDLIY EEFLRLSAES
NGKTRAVVAF EKNLEMYEQQ IDVQIKFQGF ALPHEKHYLK KNWELLNSRI QALKENKEKL
CHEIDAFSAK MKEIESELNA LKPELYQLYR KRDCIIRLLL ERGVSAAFVQ KLLFQNLTKD
DSLGLTFEDD PCLRAMVGSL RETLAEKLTI NCYDSKNWLI PECSKLECAR LLMNKNDGTF
LVRCSESRVG FYALSVVCSG RTFTCLIECR DGRYGFVGTD TYFPSLSDLI LHYSAHPLKD
HNPNLNTVLK YPVLTVLPDT STQRM
//
