ID A0A0V0V4Q0_9BILA Unreviewed; 620 AA.
AC A0A0V0V4Q0;
DT 16-MAR-2016, integrated into UniProtKB/TrEMBL.
DT 16-MAR-2016, sequence version 1.
DT 05-FEB-2025, entry version 19.
DE SubName: Full=Sodium/nucleoside cotransporter 2 {ECO:0000313|EMBL:KRX58502.1};
DE Flags: Fragment;
GN ORFNames=T09_1282 {ECO:0000313|EMBL:KRX58502.1};
OS Trichinella sp. T9.
OC Eukaryota; Metazoa; Ecdysozoa; Nematoda; Enoplea; Dorylaimia;
OC Trichinellida; Trichinellidae; Trichinella.
OX NCBI_TaxID=181606 {ECO:0000313|EMBL:KRX58502.1, ECO:0000313|Proteomes:UP000054681};
RN [1] {ECO:0000313|EMBL:KRX58502.1, ECO:0000313|Proteomes:UP000054681}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ISS409 {ECO:0000313|EMBL:KRX58502.1};
RA Korhonen P.K., Edoardo P., Giuseppe L.R., Gasser R.B.;
RT "Evolution of Trichinella species and genotypes.";
RL Submitted (JAN-2015) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBCELLULAR LOCATION: Cell membrane {ECO:0000256|ARBA:ARBA00004651};
CC Multi-pass membrane protein {ECO:0000256|ARBA:ARBA00004651}.
CC -!- SIMILARITY: Belongs to the concentrative nucleoside transporter (CNT)
CC (TC 2.A.41) family. {ECO:0000256|ARBA:ARBA00009033}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:KRX58502.1}.
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DR EMBL; JYDN01000085; KRX58502.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A0V0V4Q0; -.
DR Proteomes; UP000054681; Unassembled WGS sequence.
DR GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0005415; F:nucleoside:sodium symporter activity; IEA:TreeGrafter.
DR InterPro; IPR008276; C_nuclsd_transpt.
DR InterPro; IPR011657; CNT_C_dom.
DR InterPro; IPR002668; CNT_N_dom.
DR InterPro; IPR011642; Gate_dom.
DR PANTHER; PTHR10590; SODIUM/NUCLEOSIDE COTRANSPORTER; 1.
DR PANTHER; PTHR10590:SF4; SOLUTE CARRIER FAMILY 28 MEMBER 3; 1.
DR Pfam; PF07670; Gate; 1.
DR Pfam; PF07662; Nucleos_tra2_C; 1.
DR Pfam; PF01773; Nucleos_tra2_N; 1.
PE 3: Inferred from homology;
KW Cell membrane {ECO:0000256|ARBA:ARBA00022475};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000054681};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}.
FT TRANSMEM 66..88
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 94..111
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 145..164
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 170..186
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 198..217
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 259..281
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 309..330
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 337..358
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 364..384
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 428..450
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 462..487
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 577..596
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 174..246
FT /note="Concentrative nucleoside transporter N-terminal"
FT /evidence="ECO:0000259|Pfam:PF01773"
FT DOMAIN 262..358
FT /note="Nucleoside transporter/FeoB GTPase Gate"
FT /evidence="ECO:0000259|Pfam:PF07670"
FT DOMAIN 364..593
FT /note="Concentrative nucleoside transporter C-terminal"
FT /evidence="ECO:0000259|Pfam:PF07662"
FT NON_TER 1
FT /evidence="ECO:0000313|EMBL:KRX58502.1"
SQ SEQUENCE 620 AA; 68825 MW; 55A9E914642221DE CRC64;
LELIDEIIEI IKDEKNNDQK RISSSLSTED SFDVEKMESN NHSSLNSIST RCNKYFPRLD
EKKKRLFKII FIILLLILYH IYLGFAIARS FQNALAIVVL TILAWLLVLY YKVLRPYCFP
KFIAQHCCST LALRCKQKNK KSLQIILYAI IALAILAIIL VSVWDKWQRL NSLVGFITIV
ALLYIFSEHT SKVNWRPVFW GFGIQFLIGI IAIKWKNGMQ AFQWISDQVI IFLDYSQEGA
TFVYGFLTRP PMICGMDPVL MFSALQAIMF FSAVVAILYH LRVMQFVLAK LAWLMQITLR
TTSAESLHAV ASIILGMCET AIMITPYLPV QTNSEMFAIL CSGFGTSAAS MFAAYSSFGI
CPQYLLIVSI MAAPASLACS KLFYPETEKS QSTNISEFAN QKSPYKNILD AIGSGASEAI
MVVLENGACL VVFISLLAFV NAVISWLGAM VGLEGLTLEV MINAYCCSLR VMILSYIFFP
IAFLMGVSDE TNMQERIAET LIVSELMGTN VVLNEFIAFQ KLGEFIKAGK LSARAQMMAT
FALCNFSNLG SIGIQLGTYA SVCAEQRVTV SRLALKAMIA GCAVAFTSAC LAGMLVETPQ
FCNAQSAGSF HCFNLTSALQ
//
