ID A0A103XFY3_CYNCS Unreviewed; 471 AA.
AC A0A103XFY3;
DT 13-APR-2016, integrated into UniProtKB/TrEMBL.
DT 13-APR-2016, sequence version 1.
DT 08-OCT-2025, entry version 39.
DE SubName: Full=WD40 repeat-containing protein {ECO:0000313|EMBL:KVH90045.1};
GN ORFNames=Ccrd_007954 {ECO:0000313|EMBL:KVH90045.1};
OS Cynara cardunculus var. scolymus (Globe artichoke) (Cynara scolymus).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC asterids; campanulids; Asterales; Asteraceae; Carduoideae; Cardueae;
OC Carduinae; Cynara.
OX NCBI_TaxID=59895 {ECO:0000313|EMBL:KVH90045.1, ECO:0000313|Proteomes:UP000243975};
RN [1] {ECO:0000313|EMBL:KVH90045.1, ECO:0000313|Proteomes:UP000243975}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=2C {ECO:0000313|EMBL:KVH90045.1};
RX PubMed=26786968; DOI=10.1038/srep19427;
RA Scaglione D., Reyes-Chin-Wo S., Acquadro A., Froenicke L., Portis E.,
RA Beitel C., Tirone M., Mauro R., Lo Monaco A., Mauromicale G., Faccioli P.,
RA Cattivelli L., Rieseberg L., Michelmore R., Lanteri S.;
RT "The genome sequence of the outbreeding globe artichoke constructed de novo
RT incorporating a phase-aware low-pass sequencing strategy of F1 progeny.";
RL Sci. Rep. 6:19427-19427(2016).
CC -!- PATHWAY: Protein modification; protein ubiquitination.
CC {ECO:0000256|ARBA:ARBA00004906}.
CC -!- SIMILARITY: Belongs to the WD repeat CDC20/Fizzy family.
CC {ECO:0000256|ARBA:ARBA00006445}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:KVH90045.1}.
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DR EMBL; LEKV01005118; KVH90045.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A103XFY3; -.
DR STRING; 59895.A0A103XFY3; -.
DR Gramene; KVH90045; KVH90045; Ccrd_007954.
DR OMA; GKHDNRV; -.
DR OrthoDB; 10263272at2759; -.
DR UniPathway; UPA00143; -.
DR Proteomes; UP000243975; Unassembled WGS sequence.
DR GO; GO:0005680; C:anaphase-promoting complex; IEA:TreeGrafter.
DR GO; GO:0010997; F:anaphase-promoting complex binding; IEA:InterPro.
DR GO; GO:1990757; F:ubiquitin ligase activator activity; IEA:TreeGrafter.
DR GO; GO:0031145; P:anaphase-promoting complex-dependent catabolic process; IEA:TreeGrafter.
DR GO; GO:0051301; P:cell division; IEA:UniProtKB-KW.
DR GO; GO:1905786; P:positive regulation of anaphase-promoting complex-dependent catabolic process; IEA:TreeGrafter.
DR GO; GO:0016567; P:protein ubiquitination; IEA:UniProtKB-UniPathway.
DR FunFam; 2.130.10.10:FF:000025; FIZZY-related 2 isoform 1; 1.
DR Gene3D; 2.130.10.10; YVTN repeat-like/Quinoprotein amine dehydrogenase; 1.
DR InterPro; IPR033010; Cdc20/Fizzy.
DR InterPro; IPR015943; WD40/YVTN_repeat-like_dom_sf.
DR InterPro; IPR056150; WD40_CDC20-Fz.
DR InterPro; IPR036322; WD40_repeat_dom_sf.
DR InterPro; IPR001680; WD40_rpt.
DR PANTHER; PTHR19918; CELL DIVISION CYCLE 20 CDC20 FIZZY -RELATED; 1.
DR PANTHER; PTHR19918:SF1; FIZZY-RELATED PROTEIN HOMOLOG; 1.
DR Pfam; PF24807; WD40_CDC20-Fz; 1.
DR SMART; SM00320; WD40; 6.
DR SUPFAM; SSF50978; WD40 repeat-like; 1.
DR PROSITE; PS50082; WD_REPEATS_2; 3.
DR PROSITE; PS50294; WD_REPEATS_REGION; 2.
PE 3: Inferred from homology;
KW Cell cycle {ECO:0000256|ARBA:ARBA00023306};
KW Cell division {ECO:0000256|ARBA:ARBA00022618};
KW Mitosis {ECO:0000256|ARBA:ARBA00022776};
KW Reference proteome {ECO:0000313|Proteomes:UP000243975};
KW Repeat {ECO:0000256|ARBA:ARBA00022737};
KW WD repeat {ECO:0000256|ARBA:ARBA00022574, ECO:0000256|PROSITE-
KW ProRule:PRU00221}.
FT DOMAIN 156..445
FT /note="CDC20/Fizzy WD40"
FT /evidence="ECO:0000259|Pfam:PF24807"
FT REPEAT 201..242
FT /note="WD"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00221"
FT REPEAT 284..325
FT /note="WD"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00221"
FT REPEAT 414..446
FT /note="WD"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00221"
FT REGION 1..24
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 49..70
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 451..471
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1..17
FT /note="Low complexity"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 471 AA; 51641 MW; 0F0616D394B6E7EE CRC64;
MNNQSSSQNQ NPTTPSSKIS SLNYYHPSPS RTIYSDRFIP SRSASNFALF GISPPPTSDG
GHGDDTSSSS SNYTALLRNA LFGPDLGFVP PSTPDKKNFT IATTTPVSRN IFRFKSETRQ
SLHSLSPFGV DNQLPGVSHR PAKSPRIVPR SPYKVLDAPA LQDDFYLNLV DWSSHNVLAV
GLGNCVYLLN AFSSKVTQLC DLGVDDTVCS VGWAHQGTSL AVGTSNGKVQ IWDVFHCKRV
RTMEGHRSRV GALAWSSSML SSGSRDKSVL QRDPRAQQDF VSKLNGHKSE VCGLKWSHDN
RELASGGNDN RLFVWNQHST QPVLKYCEHT AAVKAIAWSP HLYGLLASGG GTADRCIRFW
NTSTNSHLNC VDTGSQVCNL VWSKNGNELV STHGYSQNQV IVWRYPSMSK LATLTGHTYR
VLYLAISPDG QTIVTGAGDE TLRFWNAFPS PKSQNRESKI GASSFGRTHI R
//
