ID   A0A133VN83_9EURY        Unreviewed;       548 AA.
AC   A0A133VN83;
DT   06-JUL-2016, integrated into UniProtKB/TrEMBL.
DT   06-JUL-2016, sequence version 1.
DT   02-APR-2025, entry version 22.
DE   RecName: Full=CARDB domain-containing protein {ECO:0000259|Pfam:PF07705};
GN   ORFNames=AKJ58_01510 {ECO:0000313|EMBL:KXB07904.1};
OS   candidate division MSBL1 archaeon SCGC-AAA385D11.
OC   Archaea; Methanobacteriati; Methanobacteriota; candidate division MSBL1.
OX   NCBI_TaxID=1698286 {ECO:0000313|EMBL:KXB07904.1, ECO:0000313|Proteomes:UP000070256};
RN   [1] {ECO:0000313|EMBL:KXB07904.1, ECO:0000313|Proteomes:UP000070256}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=SCGC-AAA385D11 {ECO:0000313|EMBL:KXB07904.1};
RX   PubMed=26758088; DOI=10.1038/srep19181;
RA   Mwirichia R., Alam I., Rashid M., Vinu M., Ba-Alawi W., Anthony Kamau A.,
RA   Kamanda Ngugi D., Goker M., Klenk H.P., Bajic V., Stingl U.;
RT   "Metabolic traits of an uncultured archaeal lineage -MSBL1- from brine
RT   pools of the Red Sea.";
RL   Sci. Rep. 6:19181-19181(2016).
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:KXB07904.1}.
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DR   EMBL; LHYK01000024; KXB07904.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A133VN83; -.
DR   PATRIC; fig|1698286.3.peg.207; -.
DR   Proteomes; UP000070256; Unassembled WGS sequence.
DR   GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR   Gene3D; 2.60.40.10; Immunoglobulins; 3.
DR   InterPro; IPR011635; CARDB.
DR   InterPro; IPR013783; Ig-like_fold.
DR   InterPro; IPR035986; PKD_dom_sf.
DR   Pfam; PF07705; CARDB; 1.
DR   Pfam; PF09136; Glucodextran_B; 1.
DR   Pfam; PF22352; K319L-like_PKD; 1.
DR   SUPFAM; SSF49299; PKD domain; 1.
PE   4: Predicted;
KW   Membrane {ECO:0000256|SAM:Phobius};
KW   Reference proteome {ECO:0000313|Proteomes:UP000070256};
KW   Transmembrane {ECO:0000256|SAM:Phobius};
KW   Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM        517..540
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   DOMAIN          423..501
FT                   /note="CARDB"
FT                   /evidence="ECO:0000259|Pfam:PF07705"
FT   REGION          188..224
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        189..203
FT                   /note="Low complexity"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   548 AA;  57447 MW;  AD1FCC73C323E188 CRC64;
     MPAPIGTEVV AKVGGEVKGT LTTVQTGAYG DVDNIQIDDL TVSDDLEDGD TIHFWVNGLD
     TGQTAEFSSG GDTKLNLTVE DNVAPVVTID SVTTPTNVDT QTITGAFDEA FIDTIVVNGV
     GASIDEDAGT YSADVPLDEG TNEITVEATD LVGNAGTATA TIEFVPPNRP PTADANGPYS
     VNEEETVALD GTGSSDPDGD TLTHSWSIAD DPTGEASLTD TDTSTPVFRA PSIESDTNVI
     VELTVGDGHG HTDSDTATVT ILALPPAPPA KVVENMTPEN AAENLAASDP VSAAGTLENV
     AVENAARIVD AGVKAGLTDE MAAILDETDT ESAANLLLAI YDLPETPEAA AELLGAMSLD
     KGTAVVQSFI ARAWFEYVDG TFTHLSDENI NDIYEGLTVE QRGELYPELS QSVKERISAE
     LAPRFEVSNL EISKPEVETG ETTTISVDVT NTGGTPYTYT AELSVENELV DSENVALDPD
     ESGTVSFDVS REEAGTYDFS VDGLTGSFEV EKPPKPFPWP TVTAIIVVII AVVAIAAWYW
     MQRRGGGI
//