ID A0A143PQW0_LUTPR Unreviewed; 629 AA.
AC A0A143PQW0;
DT 08-JUN-2016, integrated into UniProtKB/TrEMBL.
DT 08-JUN-2016, sequence version 1.
DT 28-JAN-2026, entry version 40.
DE RecName: Full=Selenocysteine-specific elongation factor {ECO:0000256|ARBA:ARBA00015953};
DE AltName: Full=SelB translation factor {ECO:0000256|ARBA:ARBA00031615};
GN Name=selB {ECO:0000313|EMBL:AMY11002.1};
GN ORFNames=LuPra_04246 {ECO:0000313|EMBL:AMY11002.1};
OS Luteitalea pratensis.
OC Bacteria; Pseudomonadati; Acidobacteriota; Vicinamibacteria;
OC Vicinamibacterales; Vicinamibacteraceae; Luteitalea.
OX NCBI_TaxID=1855912 {ECO:0000313|EMBL:AMY11002.1, ECO:0000313|Proteomes:UP000076079};
RN [1] {ECO:0000313|EMBL:AMY11002.1, ECO:0000313|Proteomes:UP000076079}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=DSM 100886 HEG_-6_39 {ECO:0000313|Proteomes:UP000076079};
RX PubMed=27231379;
RA Huang S., Vieira S., Bunk B., Riedel T., Sproer C., Overmann J.;
RT "First Complete Genome Sequence of a Subdivision 6 Acidobacterium Strain.";
RL Genome Announc. 4:0-0(2016).
RN [2] {ECO:0000313|Proteomes:UP000076079}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=DSM 100886 HEG_-6_39 {ECO:0000313|Proteomes:UP000076079};
RA Huang S., Vieira S., Bunk B., Riedel T., Sproeer C., Overmann J.;
RT "First Complete Genome Sequence of a Subdivision 6 Acidobacterium.";
RL Submitted (APR-2016) to the EMBL/GenBank/DDBJ databases.
CC -!- FUNCTION: Translation factor necessary for the incorporation of
CC selenocysteine into proteins. It probably replaces EF-Tu for the
CC insertion of selenocysteine directed by the UGA codon. SelB binds GTP
CC and GDP. {ECO:0000256|ARBA:ARBA00025526}.
CC -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000256|ARBA:ARBA00004496}.
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DR EMBL; CP015136; AMY11002.1; -; Genomic_DNA.
DR RefSeq; WP_110172591.1; NZ_CP015136.1.
DR AlphaFoldDB; A0A143PQW0; -.
DR STRING; 1855912.LuPra_04246; -.
DR KEGG; abac:LuPra_04246; -.
DR PATRIC; fig|1813736.3.peg.4486; -.
DR OrthoDB; 9804504at2; -.
DR Proteomes; UP000076079; Chromosome.
DR GO; GO:0005829; C:cytosol; IEA:TreeGrafter.
DR GO; GO:0005525; F:GTP binding; IEA:UniProtKB-KW.
DR GO; GO:0003924; F:GTPase activity; IEA:InterPro.
DR GO; GO:0003723; F:RNA binding; IEA:InterPro.
DR GO; GO:0003746; F:translation elongation factor activity; IEA:InterPro.
DR GO; GO:0001514; P:selenocysteine incorporation; IEA:InterPro.
DR CDD; cd04171; SelB; 1.
DR CDD; cd03696; SelB_II; 1.
DR CDD; cd15491; selB_III; 1.
DR Gene3D; 1.10.10.2770; -; 1.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 1.
DR Gene3D; 2.40.30.10; Translation factors; 1.
DR Gene3D; 1.10.10.10; Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain; 1.
DR InterPro; IPR057335; Beta-barrel_SelB.
DR InterPro; IPR050055; EF-Tu_GTPase.
DR InterPro; IPR004161; EFTu-like_2.
DR InterPro; IPR015190; Elong_fac_SelB-wing-hlx_typ-2.
DR InterPro; IPR031157; G_TR_CS.
DR InterPro; IPR027417; P-loop_NTPase.
DR InterPro; IPR015191; SelB_WHD4.
DR InterPro; IPR005225; Small_GTP-bd.
DR InterPro; IPR000795; T_Tr_GTP-bd_dom.
DR InterPro; IPR009000; Transl_B-barrel_sf.
DR InterPro; IPR009001; Transl_elong_EF1A/Init_IF2_C.
DR InterPro; IPR004535; Transl_elong_SelB.
DR InterPro; IPR036388; WH-like_DNA-bd_sf.
DR InterPro; IPR036390; WH_DNA-bd_sf.
DR NCBIfam; TIGR00475; selB; 1.
DR NCBIfam; TIGR00231; small_GTP; 1.
DR PANTHER; PTHR43721:SF22; ELONGATION FACTOR TU, MITOCHONDRIAL; 1.
DR PANTHER; PTHR43721; ELONGATION FACTOR TU-RELATED; 1.
DR Pfam; PF25461; Beta-barrel_SelB; 1.
DR Pfam; PF00009; GTP_EFTU; 1.
DR Pfam; PF03144; GTP_EFTU_D2; 1.
DR Pfam; PF09106; WHD_2nd_SelB; 1.
DR Pfam; PF09107; WHD_3rd_SelB; 1.
DR SUPFAM; SSF50465; EF-Tu/eEF-1alpha/eIF2-gamma C-terminal domain; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR SUPFAM; SSF50447; Translation proteins; 1.
DR SUPFAM; SSF46785; Winged helix' DNA-binding domain; 2.
DR PROSITE; PS00301; G_TR_1; 1.
DR PROSITE; PS51722; G_TR_2; 1.
PE 4: Predicted;
KW Cytoplasm {ECO:0000256|ARBA:ARBA00022490};
KW GTP-binding {ECO:0000256|ARBA:ARBA00023134};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741};
KW Protein biosynthesis {ECO:0000256|ARBA:ARBA00022917};
KW Reference proteome {ECO:0000313|Proteomes:UP000076079}.
FT DOMAIN 1..173
FT /note="Tr-type G"
FT /evidence="ECO:0000259|PROSITE:PS51722"
SQ SEQUENCE 629 AA; 67396 MW; 506E9E66108C0BA1 CRC64;
MTHLTIATAG HIDHGKSALV QALTGTNPDR LPEEQARGIS IELGFAHVTV GDVTLSFVDV
PGHERFVRTM LAGVGGIDAV LLVVAADESV MPQTREHFDI CRLLDVRSGV IALTRCDLAD
EMMQAVAESD VQELVAGTPL ASAPIVRVSA RTGEGLEALR RALVRCGDSR RLRRSDVPAR
LPIDRAFTVK GFGTVVTGTL WSGSIELETE LTLWPAGQAV RVRGLQVHGA PAARADAGQR
VAVNLASVAL EQVERGHVLL GDGVALSTRR MAVDVEILPD APAQKHGTRV HVHLGTSVVL
GRLILPGREA TGEVRVLAPG EGGAALLRLE APLPPRRGDR LVLRSYSPVT TIGGACVTDP
LPPPRMLHRA GTPHEDSAAL VLSRVRERGT FGCPEAELPA RCGLPPATTH QVIRELEARG
QLVSLGSYWV DADVMPEMRA TLLKIIDTAH ASDPLQAGIP RASLRVAAGR RWRPELVDLV
LSRLVREGVV AGDDRIARVA AAPAGRDPLE TRVLALIEAA ALQGLSLPEL EAALPGIDRK
GTATMLARLV KTREVERLGD LCVSASRLKG LTDELRRLAG TGEVPARIEV GWFKERYGLT
RRAAIPLLEW LDRTRVTRRE GEARVLTGT
//
