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Database: UniProt
Entry: A0A143ZZC7_PLAF7
LinkDB: A0A143ZZC7_PLAF7
Original site: A0A143ZZC7_PLAF7 
ID   A0A143ZZC7_PLAF7        Unreviewed;       585 AA.
AC   A0A143ZZC7;
DT   08-JUN-2016, integrated into UniProtKB/TrEMBL.
DT   08-JUN-2016, sequence version 1.
DT   02-JUN-2021, entry version 22.
DE   RecName: Full=S-antigen protein {ECO:0000256|ARBA:ARBA00015853};
GN   ORFNames=PF3D7_1035200 {ECO:0000313|EMBL:CZT98609.1};
OS   Plasmodium falciparum (isolate 3D7).
OC   Eukaryota; Sar; Alveolata; Apicomplexa; Aconoidasida; Haemosporida;
OC   Plasmodiidae; Plasmodium; Plasmodium (Laverania).
OX   NCBI_TaxID=36329 {ECO:0000313|EMBL:CZT98609.1, ECO:0000313|Proteomes:UP000001450};
RN   [1] {ECO:0000313|EMBL:CZT98609.1, ECO:0000313|Proteomes:UP000001450}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=Isolate 3D7 {ECO:0000313|Proteomes:UP000001450};
RX   PubMed=12368864; DOI=10.1038/nature01097;
RA   Gardner M.J., Hall N., Fung E., White O., Berriman M., Hyman R.W.,
RA   Carlton J.M., Pain A., Nelson K.E., Bowman S., Paulsen I.T., James K.D.,
RA   Eisen J.A., Rutherford K.M., Salzberg S.L., Craig A., Kyes S., Chan M.-S.,
RA   Nene V., Shallom S.J., Suh B., Peterson J., Angiuoli S., Pertea M.,
RA   Allen J., Selengut J., Haft D., Mather M.W., Vaidya A.B., Martin D.M.A.,
RA   Fairlamb A.H., Fraunholz M.J., Roos D.S., Ralph S.A., McFadden G.I.,
RA   Cummings L.M., Subramanian G.M., Mungall C., Venter J.C., Carucci D.J.,
RA   Hoffman S.L., Newbold C., Davis R.W., Fraser C.M., Barrell B.G.;
RT   "Genome sequence of the human malaria parasite Plasmodium falciparum.";
RL   Nature 419:498-511(2002).
CC   -!- FUNCTION: S antigens are soluble heat-stable proteins present in the
CC       sera of some infected individuals. {ECO:0000256|ARBA:ARBA00003457}.
CC   -!- SUBCELLULAR LOCATION: Parasitophorous vacuole
CC       {ECO:0000256|ARBA:ARBA00004290}. Vacuole
CC       {ECO:0000256|ARBA:ARBA00004116}.
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DR   EMBL; LN999944; CZT98609.1; -; Genomic_DNA.
DR   RefSeq; XP_001347627.1; XM_001347591.1.
DR   SMR; A0A143ZZC7; -.
DR   EnsemblProtists; CZT98609; CZT98609; PF3D7_1035200.
DR   GeneID; 810500; -.
DR   KEGG; pfa:PF3D7_1035200; -.
DR   VEuPathDB; PlasmoDB:PF3D7_1035200; -.
DR   OMA; QGTEQGT; -.
DR   PhylomeDB; A0A143ZZC7; -.
DR   Proteomes; UP000001450; Chromosome 10.
DR   GO; GO:0020003; C:symbiont-containing vacuole; IEA:UniProtKB-SubCell.
DR   GO; GO:0005773; C:vacuole; IEA:UniProtKB-SubCell.
DR   InterPro; IPR008825; S-antigen.
DR   Pfam; PF05756; S-antigen; 1.
PE   4: Predicted;
KW   Reference proteome {ECO:0000313|Proteomes:UP000001450};
KW   Repeat {ECO:0000256|ARBA:ARBA00022737};
KW   Signal {ECO:0000256|ARBA:ARBA00022729}.
FT   DOMAIN          1..92
FT                   /note="S-antigen"
FT                   /evidence="ECO:0000259|Pfam:PF05756"
FT   REGION          51..585
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        62..81
FT                   /note="Acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        82..117
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        126..469
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        478..573
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   585 AA;  62947 MW;  318A9ABB83711A28 CRC64;
     MNRILSVTLC LFFIYLYIYK TYGKVKNTDE GLSNIYGAKY YLRSGLFNEK NGKGQKYEDL
     EEEKEGENDD EEDSNSEESN NDEENELIKG QEGVEQETHG SEDEVSNGRE DKVSNGGEDE
     VSNGGEDEVS NGREDKVSNG GEDEVSNGRE DKVSNGGEDE VSNGREDKVS NGGEDEVSNG
     REDKVSNGGE DEVSNGREDK VSNGREDKVS NGGEDEVSNG REDKVSNGRE DKVSNGGEDE
     VSNGREDKVS NGGEDEVSNG REDKVSNGGE DEVSNGREDK VSNGREDEVS NGREDKVSNG
     GEDEVSNGRE DKVSNGGEDE VSNGREDKVS NGREDKVSNG GEDEVSNGRE DKVSNGGEDE
     VSNGREDKVS NGREDKVSNG REDEVSNGRE DKVSNGGEDE VSNGREDKVS NGREDKVSNG
     GEDEVSNGRE DKVSNGGEDE VSNGREDKVS NGREDKVSNG REDKVSNGGE DEVSNGGEDE
     VSNGREDKVS NGGEDEVSNG REDKVSNGGE DEVSNGREDK VSNGGEDEVS NGREDKVSNG
     REDEVSNGRE DKGGAGTDGE LSHNSESHTK NKKSKNSIIN MLIGM
//
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