ID A0A151GFR6_DRECN Unreviewed; 505 AA.
AC A0A151GFR6;
DT 08-JUN-2016, integrated into UniProtKB/TrEMBL.
DT 08-JUN-2016, sequence version 1.
DT 28-JAN-2026, entry version 27.
DE SubName: Full=Sphingosine kinase {ECO:0000313|EMBL:KYK55924.1};
GN ORFNames=DCS_07889 {ECO:0000313|EMBL:KYK55924.1};
OS Drechmeria coniospora (Nematophagous fungus) (Meria coniospora).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Sordariomycetes;
OC Hypocreomycetidae; Hypocreales; Ophiocordycipitaceae; Drechmeria.
OX NCBI_TaxID=98403 {ECO:0000313|EMBL:KYK55924.1, ECO:0000313|Proteomes:UP000076580};
RN [1] {ECO:0000313|EMBL:KYK55924.1, ECO:0000313|Proteomes:UP000076580}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ARSEF 6962 {ECO:0000313|EMBL:KYK55924.1,
RC ECO:0000313|Proteomes:UP000076580};
RX PubMed=26975455; DOI=10.1038/srep23122;
RA Zhang L., Zhou Z., Guo Q., Fokkens L., Miskei M., Pocsi I., Zhang W.,
RA Chen M., Wang L., Sun Y., Donzelli B.G., Gibson D.M., Nelson D.R.,
RA Luo J.G., Rep M., Liu H., Yang S., Wang J., Krasnoff S.B., Xu Y.,
RA Molnar I., Lin M.;
RT "Insights into Adaptations to a Near-Obligate Nematode Endoparasitic
RT Lifestyle from the Finished Genome of Drechmeria coniospora.";
RL Sci. Rep. 6:23122-23122(2016).
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:KYK55924.1}.
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DR EMBL; LAYC01000003; KYK55924.1; -; Genomic_DNA.
DR RefSeq; XP_040655276.1; XM_040805172.1.
DR AlphaFoldDB; A0A151GFR6; -.
DR FunCoup; A0A151GFR6; 547.
DR STRING; 98403.A0A151GFR6; -.
DR GeneID; 63720532; -.
DR InParanoid; A0A151GFR6; -.
DR Proteomes; UP000076580; Chromosome 03.
DR GO; GO:0005737; C:cytoplasm; IEA:TreeGrafter.
DR GO; GO:0016020; C:membrane; IEA:TreeGrafter.
DR GO; GO:0001727; F:lipid kinase activity; IEA:TreeGrafter.
DR GO; GO:0016773; F:phosphotransferase activity, alcohol group as acceptor; IEA:UniProtKB-ARBA.
DR GO; GO:0046512; P:sphingosine biosynthetic process; IEA:TreeGrafter.
DR Gene3D; 2.60.200.40; -; 1.
DR Gene3D; 3.40.50.10330; Probable inorganic polyphosphate/atp-NAD kinase, domain 1; 1.
DR InterPro; IPR017438; ATP-NAD_kinase_N.
DR InterPro; IPR001206; Diacylglycerol_kinase_cat_dom.
DR InterPro; IPR055916; DUF7493.
DR InterPro; IPR050187; Lipid_Phosphate_FormReg.
DR InterPro; IPR016064; NAD/diacylglycerol_kinase_sf.
DR PANTHER; PTHR12358:SF31; ACYLGLYCEROL KINASE, MITOCHONDRIAL; 1.
DR PANTHER; PTHR12358; SPHINGOSINE KINASE; 1.
DR Pfam; PF00781; DAGK_cat; 1.
DR Pfam; PF24321; DUF7493; 1.
DR SMART; SM00046; DAGKc; 1.
DR SUPFAM; SSF111331; NAD kinase/diacylglycerol kinase-like; 1.
DR PROSITE; PS50146; DAGK; 1.
PE 4: Predicted;
KW Kinase {ECO:0000313|EMBL:KYK55924.1};
KW Reference proteome {ECO:0000313|Proteomes:UP000076580};
KW Transferase {ECO:0000313|EMBL:KYK55924.1}.
FT DOMAIN 125..264
FT /note="DAGKc"
FT /evidence="ECO:0000259|PROSITE:PS50146"
SQ SEQUENCE 505 AA; 55418 MW; EA842E8081F9C322 CRC64;
MDNGNFIRSS DALSLALSDN RELTISRGHL VLHDPAAEKS QRSSSSCIAI TTDASGKKLI
PLYNILWAEV LGSQLYVDYA AQSSKTTIKL EKWVYDTDAT TKTCHGPTAN EFVSALNSRA
YADAQAKKRA LVLINPNAGP GGALRKWDRD VKPLFDAARM HMDIVVLSRG GEAAELAENI
NIERYDTIVA CSGDGTPHEI FNGLARRPDA QVALAKIAVS HIPCGSGNAM ACNLYGSHRP
AFAALAIVKG IVTPLDLVSI TQRNRRIISF LSQALGIIAE SDLATEHLRW MGTKRFGFGV
ITRIFRKRCY PCDLAVKVEV DKKKGVRAHY QRHTTNFSHG KLRAENCKGF LNGDNQGLPP
LKYGTVEDKL PEKWELVSIW VPRLTKLQMA YMAPEMNFFS AAVASDGCMD LITIDGDLAP
LTATKILMSV ENGKFFDNPH VTYKKISAYR IIPRNQEDGY ISIDGERVPF EPFQAEVHQG
LGRVISKRGV LEGTGPAISS SLLET
//
