ID A0A157N835_9BORD Unreviewed; 500 AA.
AC A0A157N835;
DT 08-JUN-2016, integrated into UniProtKB/TrEMBL.
DT 08-JUN-2016, sequence version 1.
DT 18-JUN-2025, entry version 38.
DE SubName: Full=NADH dehydrogenase subunit M {ECO:0000313|EMBL:SAI70824.1};
DE EC=1.6.5.11 {ECO:0000313|EMBL:SAI70824.1};
DE EC=1.6.5.3 {ECO:0000313|EMBL:SAI70824.1};
GN Name=nuoM {ECO:0000313|EMBL:SAI70824.1};
GN ORFNames=SAMEA3906487_02499 {ECO:0000313|EMBL:SAI70824.1};
OS Bordetella trematum.
OC Bacteria; Pseudomonadati; Pseudomonadota; Betaproteobacteria;
OC Burkholderiales; Alcaligenaceae; Bordetella.
OX NCBI_TaxID=123899 {ECO:0000313|EMBL:SAI70824.1, ECO:0000313|Proteomes:UP000076825};
RN [1] {ECO:0000313|EMBL:SAI70824.1, ECO:0000313|Proteomes:UP000076825}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=H044680328 {ECO:0000313|EMBL:SAI70824.1,
RC ECO:0000313|Proteomes:UP000076825};
RG Pathogen Informatics;
RL Submitted (APR-2016) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBCELLULAR LOCATION: Endomembrane system
CC {ECO:0000256|ARBA:ARBA00004127}; Multi-pass membrane protein
CC {ECO:0000256|ARBA:ARBA00004127}. Membrane
CC {ECO:0000256|RuleBase:RU000320}; Multi-pass membrane protein
CC {ECO:0000256|RuleBase:RU000320}.
CC -!- SIMILARITY: Belongs to the complex I subunit 4 family.
CC {ECO:0000256|ARBA:ARBA00009025}.
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DR EMBL; LT546645; SAI70824.1; -; Genomic_DNA.
DR RefSeq; WP_025518021.1; NZ_UYIW01000004.1.
DR AlphaFoldDB; A0A157N835; -.
DR STRING; 123899.SAMEA3906487_02499; -.
DR KEGG; btrm:SAMEA390648702499; -.
DR PATRIC; fig|123899.6.peg.2486; -.
DR eggNOG; COG1008; Bacteria.
DR OrthoDB; 9768329at2; -.
DR Proteomes; UP000076825; Chromosome 1.
DR GO; GO:0012505; C:endomembrane system; IEA:UniProtKB-SubCell.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0008137; F:NADH dehydrogenase (ubiquinone) activity; IEA:InterPro.
DR GO; GO:0048039; F:ubiquinone binding; IEA:TreeGrafter.
DR GO; GO:0042773; P:ATP synthesis coupled electron transport; IEA:InterPro.
DR GO; GO:0015990; P:electron transport coupled proton transport; IEA:TreeGrafter.
DR InterPro; IPR000260; NADH4_N.
DR InterPro; IPR010227; NADH_Q_OxRdtase_chainM/4.
DR InterPro; IPR003918; NADH_UbQ_OxRdtase.
DR InterPro; IPR001750; ND/Mrp_TM.
DR NCBIfam; TIGR01972; NDH_I_M; 1.
DR NCBIfam; NF004499; PRK05846.1-3; 1.
DR NCBIfam; NF004501; PRK05846.1-5; 1.
DR PANTHER; PTHR43507; NADH-UBIQUINONE OXIDOREDUCTASE CHAIN 4; 1.
DR PANTHER; PTHR43507:SF1; NADH-UBIQUINONE OXIDOREDUCTASE CHAIN 4; 1.
DR Pfam; PF01059; Oxidored_q5_N; 1.
DR Pfam; PF00361; Proton_antipo_M; 1.
DR PRINTS; PR01437; NUOXDRDTASE4.
PE 3: Inferred from homology;
KW Membrane {ECO:0000256|SAM:Phobius}; NAD {ECO:0000256|ARBA:ARBA00023027};
KW Oxidoreductase {ECO:0000313|EMBL:SAI70824.1};
KW Reference proteome {ECO:0000313|Proteomes:UP000076825};
KW Translocase {ECO:0000256|ARBA:ARBA00022967};
KW Transmembrane {ECO:0000256|RuleBase:RU000320, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT TRANSMEM 12..31
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 43..62
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 92..112
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 119..137
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 143..163
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 175..193
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 213..231
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 252..272
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 278..303
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 310..329
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 341..359
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 380..401
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 413..434
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 460..477
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 71..131
FT /note="NADH:ubiquinone oxidoreductase chain 4 N-terminal"
FT /evidence="ECO:0000259|Pfam:PF01059"
FT DOMAIN 141..423
FT /note="NADH:quinone oxidoreductase/Mrp antiporter
FT transmembrane"
FT /evidence="ECO:0000259|Pfam:PF00361"
SQ SEQUENCE 500 AA; 54723 MW; 8FC7D133092AE47A CRC64;
MMASEMASNT FPWLTLAIFV PIVFGLLVLA LGRDDRPCLT RGLSLIGAIA GFLVTIPVYT
GFDKTTAAMQ FVEKTSWIES FNVNYHLGVD GISIWFVLLT AFITIIVVAA GWEVITNRVS
QYMAAFLILS GLMVGVFSAL DGLLFYVFFE ATLIPMYIIV GVWGGPNRVY AAFKFFLYTL
LGSLLTLVAF IYLWNASGGS FDIQTWQQTK LGYTPQILIF VALFAAFAVK VPMWPVHTWL
PDAHVEAPTG GSVVLAAIML KLGAYGFLRF SLPIVPDAAH SLAGVMIALS LVAVIYIGLV
AMVQDDMKKL VAYSSVAHMG FVTLGFFVFN TAGMEGAIVQ MISHGFVSGA MFLCIGVLYD
RLHSRRIADY GGVVNVMPRF ATFFVLFSMA NSGLPATSGF VGEFMVIMGA VEHNFWVGLL
TATALIFGAA YSLWMVKRVI FGDITNDAVR TMPDLNRREF WILGVMAIAV LYMGIYPKPF
TDVMHVSVEA LLQHVAVSKL
//
