ID A0A158G683_9BURK Unreviewed; 636 AA.
AC A0A158G683;
DT 27-SEP-2017, integrated into UniProtKB/TrEMBL.
DT 27-SEP-2017, sequence version 1.
DT 28-JAN-2026, entry version 31.
DE RecName: Full=Selenocysteine-specific elongation factor {ECO:0000256|ARBA:ARBA00015953};
DE AltName: Full=SelB translation factor {ECO:0000256|ARBA:ARBA00031615};
GN ORFNames=AWB68_01281 {ECO:0000313|EMBL:SAL27139.1};
OS Caballeronia choica.
OC Bacteria; Pseudomonadati; Pseudomonadota; Betaproteobacteria;
OC Burkholderiales; Burkholderiaceae; Caballeronia.
OX NCBI_TaxID=326476 {ECO:0000313|EMBL:SAL27139.1, ECO:0000313|Proteomes:UP000054770};
RN [1] {ECO:0000313|EMBL:SAL27139.1}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=LMG 22940 {ECO:0000313|EMBL:SAL27139.1};
RA Peeters C.;
RL Submitted (JAN-2016) to the EMBL/GenBank/DDBJ databases.
CC -!- FUNCTION: Translation factor necessary for the incorporation of
CC selenocysteine into proteins. It probably replaces EF-Tu for the
CC insertion of selenocysteine directed by the UGA codon. SelB binds GTP
CC and GDP. {ECO:0000256|ARBA:ARBA00025526}.
CC -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000256|ARBA:ARBA00004496}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:SAL27139.1}.
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DR EMBL; FCON02000009; SAL27139.1; -; Genomic_DNA.
DR RefSeq; WP_087643504.1; NZ_FCON02000009.1.
DR AlphaFoldDB; A0A158G683; -.
DR OrthoDB; 9803139at2; -.
DR Proteomes; UP000054770; Unassembled WGS sequence.
DR GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR GO; GO:0005525; F:GTP binding; IEA:UniProtKB-KW.
DR GO; GO:0003924; F:GTPase activity; IEA:InterPro.
DR GO; GO:0003723; F:RNA binding; IEA:InterPro.
DR GO; GO:0003746; F:translation elongation factor activity; IEA:UniProtKB-KW.
DR GO; GO:0001514; P:selenocysteine incorporation; IEA:InterPro.
DR CDD; cd04171; SelB; 1.
DR CDD; cd03696; SelB_II; 1.
DR CDD; cd15491; selB_III; 1.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 1.
DR Gene3D; 2.40.30.10; Translation factors; 1.
DR Gene3D; 1.10.10.10; Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain; 3.
DR InterPro; IPR057335; Beta-barrel_SelB.
DR InterPro; IPR050055; EF-Tu_GTPase.
DR InterPro; IPR004161; EFTu-like_2.
DR InterPro; IPR015190; Elong_fac_SelB-wing-hlx_typ-2.
DR InterPro; IPR031157; G_TR_CS.
DR InterPro; IPR027417; P-loop_NTPase.
DR InterPro; IPR015191; SelB_WHD4.
DR InterPro; IPR000795; T_Tr_GTP-bd_dom.
DR InterPro; IPR009000; Transl_B-barrel_sf.
DR InterPro; IPR009001; Transl_elong_EF1A/Init_IF2_C.
DR InterPro; IPR004535; Transl_elong_SelB.
DR InterPro; IPR036388; WH-like_DNA-bd_sf.
DR InterPro; IPR036390; WH_DNA-bd_sf.
DR InterPro; IPR048931; WHD_2nd_SelB_bact.
DR NCBIfam; TIGR00475; selB; 1.
DR PANTHER; PTHR43721; ELONGATION FACTOR TU-RELATED; 1.
DR PANTHER; PTHR43721:SF9; GTP-BINDING PROTEIN 1; 1.
DR Pfam; PF25461; Beta-barrel_SelB; 1.
DR Pfam; PF00009; GTP_EFTU; 1.
DR Pfam; PF03144; GTP_EFTU_D2; 1.
DR Pfam; PF09106; WHD_2nd_SelB; 1.
DR Pfam; PF21214; WHD_2nd_SelB_bact; 1.
DR Pfam; PF09107; WHD_3rd_SelB; 1.
DR SUPFAM; SSF50465; EF-Tu/eEF-1alpha/eIF2-gamma C-terminal domain; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR SUPFAM; SSF50447; Translation proteins; 1.
DR SUPFAM; SSF46785; Winged helix' DNA-binding domain; 3.
DR PROSITE; PS00301; G_TR_1; 1.
DR PROSITE; PS51722; G_TR_2; 1.
PE 4: Predicted;
KW Cytoplasm {ECO:0000256|ARBA:ARBA00022490};
KW Elongation factor {ECO:0000313|EMBL:SAL27139.1};
KW GTP-binding {ECO:0000256|ARBA:ARBA00023134};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741};
KW Protein biosynthesis {ECO:0000256|ARBA:ARBA00022917};
KW Reference proteome {ECO:0000313|Proteomes:UP000054770}.
FT DOMAIN 1..173
FT /note="Tr-type G"
FT /evidence="ECO:0000259|PROSITE:PS51722"
SQ SEQUENCE 636 AA; 69290 MW; 48A42CBA303DEA44 CRC64;
MIVGTAGHID HGKTTLVRAL SGVDTDRLKE EKARGISIEL GYAYVPLDDG NVLGLIDVPG
HEKLVHTMAA GACGIDYALF VIAADDGVMP QTREHLAILE LLGVTQGAIA VTKIDRVDAG
RLKEVREEIK AWLATSTLKN APLFDTNATR DDDAGVAALD AHLREAAARW RMRRDDGLFR
LAVDRVFTLS GQGTIVTGTV FAGRVNVGDT MLLAPAGKPV RVRSIHAQNR AAQTGRAGER
CALNLAGIDK DAIARGDWIV DARLGATSER IETELTLLPD ADFSLTHWAP LHVHLGTTHQ
VAHVALLDGD TLAAGATARV QLVFDKSVCA LPGDRFIVRN AQASRTVGGG RVLDPFGPTR
KRRTPERRAW LDALHMMLEA GRIDGLLAHA PSGMRRSLLE HLSGMPAAAL ALPQGTHVVP
LPDDALFIAA ARWDALKARL IDALSAFHAR SPDEQGPDTA RLRRIAAPLV SDALWRALVD
AAVDERSIVR SGPWLHLAAH TVTLDADERA FADALLVSIE RGRFDPPWVR DLAGTHGVAE
ERVRQLLRKL ARQGEVFQVV RDLFYHRDAI RELARLIASE ASGHDGEIGA APFRDASALG
RKRAIQVLEF FDRVGYTRFH RDMHVLRVDS RWQELI
//
