ID A0A158IYA8_9BURK Unreviewed; 295 AA.
AC A0A158IYA8;
DT 27-SEP-2017, integrated into UniProtKB/TrEMBL.
DT 27-SEP-2017, sequence version 1.
DT 28-JAN-2026, entry version 27.
DE RecName: Full=hydroxymethylpyrimidine kinase {ECO:0000256|ARBA:ARBA00012135};
DE EC=2.7.1.49 {ECO:0000256|ARBA:ARBA00012135};
GN ORFNames=AWB66_03568 {ECO:0000313|EMBL:SAL61662.1};
OS Caballeronia telluris.
OC Bacteria; Pseudomonadati; Pseudomonadota; Betaproteobacteria;
OC Burkholderiales; Burkholderiaceae; Caballeronia.
OX NCBI_TaxID=326475 {ECO:0000313|EMBL:SAL61662.1, ECO:0000313|Proteomes:UP000054717};
RN [1] {ECO:0000313|EMBL:SAL61662.1}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=LMG 22936 {ECO:0000313|EMBL:SAL61662.1};
RA Peeters Charlotte.;
RL Submitted (JAN-2016) to the EMBL/GenBank/DDBJ databases.
CC -!- PATHWAY: Cofactor biosynthesis; thiamine diphosphate biosynthesis.
CC {ECO:0000256|ARBA:ARBA00004948}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:SAL61662.1}.
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DR EMBL; FCNZ02000013; SAL61662.1; -; Genomic_DNA.
DR RefSeq; WP_087631637.1; NZ_FCNZ02000013.1.
DR AlphaFoldDB; A0A158IYA8; -.
DR STRING; 326475.AWB66_03568; -.
DR UniPathway; UPA00060; UER00138.
DR Proteomes; UP000054717; Unassembled WGS sequence.
DR GO; GO:0005829; C:cytosol; IEA:TreeGrafter.
DR GO; GO:0008902; F:hydroxymethylpyrimidine kinase activity; IEA:UniProtKB-EC.
DR GO; GO:0008972; F:phosphomethylpyrimidine kinase activity; IEA:InterPro.
DR GO; GO:0009228; P:thiamine biosynthetic process; IEA:InterPro.
DR GO; GO:0009229; P:thiamine diphosphate biosynthetic process; IEA:UniProtKB-UniPathway.
DR CDD; cd01169; HMPP_kinase; 1.
DR Gene3D; 3.40.1190.20; -; 1.
DR InterPro; IPR004399; HMP/HMP-P_kinase_dom.
DR InterPro; IPR013749; PM/HMP-P_kinase-1.
DR InterPro; IPR029056; Ribokinase-like.
DR PANTHER; PTHR20858:SF17; HYDROXYMETHYLPYRIMIDINE_PHOSPHOMETHYLPYRIMIDINE KINASE THI20-RELATED; 1.
DR PANTHER; PTHR20858; PHOSPHOMETHYLPYRIMIDINE KINASE; 1.
DR Pfam; PF08543; Phos_pyr_kin; 1.
DR SUPFAM; SSF53613; Ribokinase-like; 1.
PE 4: Predicted;
KW Kinase {ECO:0000313|EMBL:SAL61662.1};
KW Reference proteome {ECO:0000313|Proteomes:UP000054717};
KW Transferase {ECO:0000313|EMBL:SAL61662.1}.
FT DOMAIN 16..255
FT /note="Pyridoxamine kinase/Phosphomethylpyrimidine kinase"
FT /evidence="ECO:0000259|Pfam:PF08543"
FT REGION 268..295
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 295 AA; 31332 MW; AEDE1E57063630A0 CRC64;
MPSDTPPIVL TFGLSDPTGG FGLQADLLTL ASMGCHGVSV LTGYTVRDSA TTDEVTGLDP
DTVATQARML LEDMPIAAFK IGAATRAEVV SAIAEVVADY DDIPLILAPD FTLDDEHVLS
ADELRESLAD LLVPQTTMLV ADHTTLLQLA QPDGDAEAPS LDAAISHLLA QGCEYILATE
TGTHRHVNTL YSEEGQVRQD TWDRSPNRMM GLTDTLGSAI AALLANGQEP AEAAREAQEY
LFQATRAAFR PGMGAYLPDR FFWARSNEMD DTDGATPPDA VADEPPPAAP GAARH
//
