ID A0A158JDU7_9BURK Unreviewed; 636 AA.
AC A0A158JDU7;
DT 27-SEP-2017, integrated into UniProtKB/TrEMBL.
DT 27-SEP-2017, sequence version 1.
DT 28-JAN-2026, entry version 29.
DE RecName: Full=Selenocysteine-specific elongation factor {ECO:0000256|ARBA:ARBA00015953};
DE AltName: Full=SelB translation factor {ECO:0000256|ARBA:ARBA00031615};
GN ORFNames=AWB66_04165 {ECO:0000313|EMBL:SAL67048.1};
OS Caballeronia telluris.
OC Bacteria; Pseudomonadati; Pseudomonadota; Betaproteobacteria;
OC Burkholderiales; Burkholderiaceae; Caballeronia.
OX NCBI_TaxID=326475 {ECO:0000313|EMBL:SAL67048.1, ECO:0000313|Proteomes:UP000054717};
RN [1] {ECO:0000313|EMBL:SAL67048.1}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=LMG 22936 {ECO:0000313|EMBL:SAL67048.1};
RA Peeters Charlotte.;
RL Submitted (JAN-2016) to the EMBL/GenBank/DDBJ databases.
CC -!- FUNCTION: Translation factor necessary for the incorporation of
CC selenocysteine into proteins. It probably replaces EF-Tu for the
CC insertion of selenocysteine directed by the UGA codon. SelB binds GTP
CC and GDP. {ECO:0000256|ARBA:ARBA00025526}.
CC -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000256|ARBA:ARBA00004496}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:SAL67048.1}.
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DR EMBL; FCNZ02000016; SAL67048.1; -; Genomic_DNA.
DR RefSeq; WP_087632064.1; NZ_FCNZ02000016.1.
DR AlphaFoldDB; A0A158JDU7; -.
DR STRING; 326475.AWB66_04165; -.
DR Proteomes; UP000054717; Unassembled WGS sequence.
DR GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR GO; GO:0005525; F:GTP binding; IEA:UniProtKB-KW.
DR GO; GO:0003924; F:GTPase activity; IEA:InterPro.
DR GO; GO:0003723; F:RNA binding; IEA:InterPro.
DR GO; GO:0003746; F:translation elongation factor activity; IEA:UniProtKB-KW.
DR GO; GO:0001514; P:selenocysteine incorporation; IEA:InterPro.
DR CDD; cd04171; SelB; 1.
DR CDD; cd03696; SelB_II; 1.
DR CDD; cd15491; selB_III; 1.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 1.
DR Gene3D; 2.40.30.10; Translation factors; 1.
DR Gene3D; 1.10.10.10; Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain; 3.
DR InterPro; IPR057335; Beta-barrel_SelB.
DR InterPro; IPR050055; EF-Tu_GTPase.
DR InterPro; IPR004161; EFTu-like_2.
DR InterPro; IPR015190; Elong_fac_SelB-wing-hlx_typ-2.
DR InterPro; IPR031157; G_TR_CS.
DR InterPro; IPR027417; P-loop_NTPase.
DR InterPro; IPR015191; SelB_WHD4.
DR InterPro; IPR000795; T_Tr_GTP-bd_dom.
DR InterPro; IPR009000; Transl_B-barrel_sf.
DR InterPro; IPR009001; Transl_elong_EF1A/Init_IF2_C.
DR InterPro; IPR004535; Transl_elong_SelB.
DR InterPro; IPR036388; WH-like_DNA-bd_sf.
DR InterPro; IPR036390; WH_DNA-bd_sf.
DR InterPro; IPR048931; WHD_2nd_SelB_bact.
DR NCBIfam; TIGR00475; selB; 1.
DR PANTHER; PTHR43721; ELONGATION FACTOR TU-RELATED; 1.
DR PANTHER; PTHR43721:SF9; GTP-BINDING PROTEIN 1; 1.
DR Pfam; PF25461; Beta-barrel_SelB; 1.
DR Pfam; PF00009; GTP_EFTU; 1.
DR Pfam; PF03144; GTP_EFTU_D2; 1.
DR Pfam; PF09106; WHD_2nd_SelB; 1.
DR Pfam; PF21214; WHD_2nd_SelB_bact; 1.
DR Pfam; PF09107; WHD_3rd_SelB; 1.
DR PRINTS; PR00315; ELONGATNFCT.
DR SUPFAM; SSF50465; EF-Tu/eEF-1alpha/eIF2-gamma C-terminal domain; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR SUPFAM; SSF50447; Translation proteins; 1.
DR SUPFAM; SSF46785; Winged helix' DNA-binding domain; 3.
DR PROSITE; PS00301; G_TR_1; 1.
DR PROSITE; PS51722; G_TR_2; 1.
PE 4: Predicted;
KW Cytoplasm {ECO:0000256|ARBA:ARBA00022490};
KW Elongation factor {ECO:0000313|EMBL:SAL67048.1};
KW GTP-binding {ECO:0000256|ARBA:ARBA00023134};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741};
KW Protein biosynthesis {ECO:0000256|ARBA:ARBA00022917};
KW Reference proteome {ECO:0000313|Proteomes:UP000054717}.
FT DOMAIN 1..173
FT /note="Tr-type G"
FT /evidence="ECO:0000259|PROSITE:PS51722"
SQ SEQUENCE 636 AA; 69827 MW; E49CAA53C530F3F5 CRC64;
MIVGTAGHID HGKTTLVRAL SGVDTDRLKE EKARGISIEL GYAYVPLANG EVLGLIDVPG
HEKLVHTMAA GACGIDFALL VIAADDGVMP QTREHLAILE LLGVRQGAVA VTKTDRVDAA
RLGHVHDEIE TWLASSTLAG APRFDTNATQ ADDPGVAALD AHLREAAARW RMRRDDGLFR
LAVDRVFTLS GQGTIVTGTV FSGRVDAGDT MLLAPRGEPV RVRSIHAQNR AAQTGRAGER
CALNLAGIEK DAIARGDWIV DARLRETSLR IDTELTLLPD AGMSLTHWAP LHVHLGTTHQ
VAHVALLDGD VLPAGDTARV QLVFDKPVCA LPGDRFIVRN AQANRTVGGG RVLDPFGPAR
KRRTPERRAW LDALSAMLET RRIDGLLVEA PYGLKRSLVE HLCGMPAESL ELPHGTRAVP
LSGDVLFVAA THWDGLQRRL VEALAAYHER SPDEQGPDMA RLRRIAAPLA PDALWRALVD
RSVEEKRIAR SGPWLHLPAH SVTLDDAERA LADVLLSTIA RGRFDPPWVR DLARAHDANE
ERVRQVLRKL ARQGEVFQVV RDLFYHRDAV RELARLVASE AAKHDGRLGA APFRDASALG
RKRAIQVLEF FDRVGYTRFH RDLHVLRVDS RWHELI
//
