ID A0A164K8Q9_9CRUS Unreviewed; 1146 AA.
AC A0A164K8Q9;
DT 06-JUL-2016, integrated into UniProtKB/TrEMBL.
DT 06-JUL-2016, sequence version 1.
DT 18-JUN-2025, entry version 27.
DE RecName: Full=Proteasomal ubiquitin receptor ADRM1 homolog {ECO:0000256|ARBA:ARBA00070663};
GN ORFNames=APZ42_034297 {ECO:0000313|EMBL:KZS03055.1};
OS Daphnia magna.
OC Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Crustacea; Branchiopoda;
OC Diplostraca; Cladocera; Anomopoda; Daphniidae; Daphnia.
OX NCBI_TaxID=35525 {ECO:0000313|EMBL:KZS03055.1, ECO:0000313|Proteomes:UP000076858};
RN [1] {ECO:0000313|EMBL:KZS03055.1, ECO:0000313|Proteomes:UP000076858}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Xinb3 {ECO:0000313|EMBL:KZS03055.1,
RC ECO:0000313|Proteomes:UP000076858};
RC TISSUE=Complete organism {ECO:0000313|EMBL:KZS03055.1};
RA Gilbert D.G., Choi J.-H., Mockaitis K., Colbourne J., Pfrender M.;
RT "EvidentialGene: Evidence-directed Construction of Genes on Genomes.";
RL Submitted (MAR-2016) to the EMBL/GenBank/DDBJ databases.
CC -!- FUNCTION: May function as a proteasomal ubiquitin receptor. May promote
CC the deubiquitinating activity associated with the 26S proteasome.
CC {ECO:0000256|ARBA:ARBA00054744}.
CC -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000256|ARBA:ARBA00004496}.
CC Nucleus {ECO:0000256|ARBA:ARBA00004123}.
CC -!- SIMILARITY: Belongs to the ADRM1 family.
CC {ECO:0000256|ARBA:ARBA00009216}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:KZS03055.1}.
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DR EMBL; LRGB01003372; KZS03055.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A164K8Q9; -.
DR STRING; 35525.A0A164K8Q9; -.
DR OrthoDB; 6437225at2759; -.
DR Proteomes; UP000076858; Unassembled WGS sequence.
DR GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR GO; GO:0008541; C:proteasome regulatory particle, lid subcomplex; IEA:TreeGrafter.
DR GO; GO:0061133; F:endopeptidase activator activity; IEA:TreeGrafter.
DR GO; GO:0070628; F:proteasome binding; IEA:TreeGrafter.
DR CDD; cd13314; PH_Rpn13; 1.
DR FunFam; 1.10.2020.20:FF:000001; Proteasomal ubiquitin receptor ADRM1; 1.
DR FunFam; 2.30.29.70:FF:000001; Proteasomal ubiquitin receptor ADRM1; 1.
DR Gene3D; 1.10.2020.20; -; 1.
DR Gene3D; 2.30.29.70; Proteasomal ubiquitin receptor Rpn13/ADRM1; 1.
DR InterPro; IPR040479; CLIP_SPH_mas.
DR InterPro; IPR044867; DEUBAD_dom.
DR InterPro; IPR006773; Rpn13/ADRM1.
DR InterPro; IPR044868; Rpn13/ADRM1_Pru.
DR InterPro; IPR038633; Rpn13/ADRM1_Pru_sf.
DR InterPro; IPR032368; RPN13_DEUBAD.
DR InterPro; IPR038108; RPN13_DEUBAD_sf.
DR PANTHER; PTHR12225; ADHESION REGULATING MOLECULE 1 110 KDA CELL MEMBRANE GLYCOPROTEIN; 1.
DR PANTHER; PTHR12225:SF0; PROTEASOMAL UBIQUITIN RECEPTOR ADRM1; 1.
DR Pfam; PF18398; CLIP_SPH_mas; 5.
DR Pfam; PF04683; Rpn13_ADRM1_Pru; 1.
DR Pfam; PF16550; RPN13_C; 1.
DR PROSITE; PS51916; DEUBAD; 1.
DR PROSITE; PS51917; PRU; 1.
PE 3: Inferred from homology;
KW Cytoplasm {ECO:0000256|ARBA:ARBA00022490};
KW Nucleus {ECO:0000256|ARBA:ARBA00023242};
KW Proteasome {ECO:0000256|ARBA:ARBA00022942};
KW Receptor {ECO:0000313|EMBL:KZS03055.1};
KW Reference proteome {ECO:0000313|Proteomes:UP000076858}.
FT DOMAIN 761..874
FT /note="Pru"
FT /evidence="ECO:0000259|PROSITE:PS51917"
FT DOMAIN 1022..1137
FT /note="DEUBAD"
FT /evidence="ECO:0000259|PROSITE:PS51916"
FT REGION 1..92
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 144..167
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 198..263
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 358..398
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 439..498
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 539..575
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 598..643
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 868..891
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 929..983
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1..16
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 26..41
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 45..75
FT /note="Low complexity"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 152..167
FT /note="Low complexity"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 454..498
FT /note="Low complexity"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 552..563
FT /note="Low complexity"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 602..622
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 929..979
FT /note="Low complexity"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1146 AA; 119023 MW; 378E6B97331EF8E2 CRC64;
MAEKSEWGKG IGDRDLFGWN AIHGQKQPSM SGAESLTSPS PSDVGGTSSN TAGSSTTATA
KANPTTSTTT GMPTTNNAKA QQPSPTPGSL ASSLLSGLFD TITSTSKSKD CPGRCVHVLA
ALLCEKVLEN VTCSEGSMRC CVENRPSPPA RSVTTKTPAV STSSVVSSSS EATTTQKVVT
TTAPTTTTTK ATTAIPTTTT ASTTTTKPTT QSTTTAKATT TTAPTTTTTK TTTTTTKPTT
TTTKAPTTTT KAPTTTTTTV KPSSTTTTVA TTTKAAVTVD SKVEDAEGGD DDEVLKASEV
GSLRICPGVC VATRISDYCE AVLNVDGLCK TAMKCCVTKS LFGESEPPPE LVILNEASST
GASTTEASTT TSRTTTTVRT TSTTTRPRPK TTTTAVPAAD DDKRCKGTCV TGFFSYLCDF
IDAKAVCANG GKCCISRREG GGGASEQKTN NVTAPASGSR PSAGSSKPSV VTSTTARPTT
AKPKATTTSA PSTTTASVPK RCPGVCLPGL MSAFCSKPSV VVNNPPNLCD RGSICCDSKT
RDSPQSGGSG SNSGSSGSTN NRPSRPPTKA PASAMSDLLS NPLTTLLAGP LLSSLAGAAM
NQRPSSSGDK SDVSPQRPQS IGTRPPPTTT TTTTTTTSAP QVVDTRPYCP GTCMAPILSF
SCFSNAEITD LFRCPSSKVV CCAQKSAIRE LKPSSPATVE VPQSEFSRLG TNREEASLEY
GDTAMICSFI FDEIVSASRL ETLVFYREEK MSLFSNSSSR SQSKNLVEFR AGKMTMRGNM
VHPDKRKGLV YIHQSSDSLI HFCWKDRQSG NVEDDWIIFP DDCEYVRVPQ CTTGRVFLLK
FKSSNKKTFF WMQEPKTDKD ETYCRKVNEY LNNPPTPGSQ GGRGGSNLGS ERDLQSLLSS
MSQQQLMQLF GNVGGMSGLS SLLVPSDSAV RSSSSSRSRS SGATSGSASQ ARSAAAIPPA
TATGATAAAT TPSSANAGSN LPATPLSTGV PSLGNLTNLQ QILSGIQVPD SALGLSGTAA
AQGQPEKPSV DLSEGLSTDV LHPILNNADF MRQLRDFLPP SDQASEGDTA SMVRDTVQSP
QFAQALSVFS AALQSGQLGP LIQQFGLGSE AVEAAQKGDM EAFIAALQSQ DKDKKKDDGD
DGMALD
//
