ID A0A168DMP6_CORDF Unreviewed; 498 AA.
AC A0A168DMP6;
DT 06-JUL-2016, integrated into UniProtKB/TrEMBL.
DT 06-JUL-2016, sequence version 1.
DT 28-JAN-2026, entry version 28.
DE SubName: Full=Sphingosine kinase {ECO:0000313|EMBL:OAA72797.1};
GN ORFNames=LEL_08581 {ECO:0000313|EMBL:OAA72797.1};
OS Akanthomyces lecanii RCEF 1005.
OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Sordariomycetes;
OC Hypocreomycetidae; Hypocreales; Cordycipitaceae; Akanthomyces;
OC Cordyceps confragosa.
OX NCBI_TaxID=1081108 {ECO:0000313|EMBL:OAA72797.1, ECO:0000313|Proteomes:UP000076881};
RN [1] {ECO:0000313|EMBL:OAA72797.1, ECO:0000313|Proteomes:UP000076881}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=RCEF 1005 {ECO:0000313|EMBL:OAA72797.1,
RC ECO:0000313|Proteomes:UP000076881};
RX PubMed=27071652; DOI=10.1093/gbe/evw082;
RA Shang Y., Xiao G., Zheng P., Cen K., Zhan S., Wang C.;
RT "Divergent and convergent evolution of fungal pathogenicity.";
RL Genome Biol. Evol. 8:1374-1387(2016).
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:OAA72797.1}.
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DR EMBL; AZHF01000007; OAA72797.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A168DMP6; -.
DR STRING; 1081108.A0A168DMP6; -.
DR OrthoDB; 3853857at2759; -.
DR Proteomes; UP000076881; Unassembled WGS sequence.
DR GO; GO:0005737; C:cytoplasm; IEA:TreeGrafter.
DR GO; GO:0016020; C:membrane; IEA:TreeGrafter.
DR GO; GO:0001727; F:lipid kinase activity; IEA:TreeGrafter.
DR GO; GO:0016773; F:phosphotransferase activity, alcohol group as acceptor; IEA:UniProtKB-ARBA.
DR GO; GO:0046512; P:sphingosine biosynthetic process; IEA:TreeGrafter.
DR Gene3D; 2.60.200.40; -; 1.
DR Gene3D; 3.40.50.10330; Probable inorganic polyphosphate/atp-NAD kinase, domain 1; 1.
DR InterPro; IPR017438; ATP-NAD_kinase_N.
DR InterPro; IPR001206; Diacylglycerol_kinase_cat_dom.
DR InterPro; IPR055916; DUF7493.
DR InterPro; IPR050187; Lipid_Phosphate_FormReg.
DR InterPro; IPR016064; NAD/diacylglycerol_kinase_sf.
DR PANTHER; PTHR12358:SF31; ACYLGLYCEROL KINASE, MITOCHONDRIAL; 1.
DR PANTHER; PTHR12358; SPHINGOSINE KINASE; 1.
DR Pfam; PF00781; DAGK_cat; 1.
DR Pfam; PF24321; DUF7493; 1.
DR SMART; SM00046; DAGKc; 1.
DR SUPFAM; SSF111331; NAD kinase/diacylglycerol kinase-like; 1.
DR PROSITE; PS50146; DAGK; 1.
PE 4: Predicted;
KW Kinase {ECO:0000313|EMBL:OAA72797.1};
KW Reference proteome {ECO:0000313|Proteomes:UP000076881};
KW Transferase {ECO:0000313|EMBL:OAA72797.1}.
FT DOMAIN 116..255
FT /note="DAGKc"
FT /evidence="ECO:0000259|PROSITE:PS50146"
SQ SEQUENCE 498 AA; 54672 MW; 62D7ECD6F5DB798B CRC64;
MSTNGAVEAP QLTLQLASGR TLTVEDSDLV LRDPSNINEK GSKRDRNGRQ TIPLYNVLWA
EVVEANLTIE YALLSDKSKF QVEKWTLPIN SADEQAQTSS ETFATALRSR AYGKAQQKRR
AYVLVNPNAG PGNGVKRWEN EVKPLFDAAR MEMDVVFLKR GGEALELVEQ MAIDKYDTVI
PCSGDGTPHE VFNGLAKRPD AKLALSKIAV GHIPCGSGNA MSCNLYGSHK PSYAALAIVK
GVVTPLDLVS ITQGDTRIIS FLSQSLGIVA EGDLGTEHLR WMGSARFDYG VISRVFRKKV
YPCDIAVQLE VEKPNVKEHY KQHASIPSLR QAATEQSDAD EASGLPELKY GTVKDDLPAG
WKLVPYDKVG TVYCGNMAYM APDVHFFPAA VAADGCMDLI TMNGDIPALK ALQAFLSVGS
NKFFDSPYVH YQKISAYRII PRNQKDGYIS IDGEKVPFEP FQAEVHQGLG RVISKRGMFE
AEGPANWDKV TISERLHA
//
