ID   A0A178ZUG4_9EURO        Unreviewed;       555 AA.
AC   A0A178ZUG4;
DT   07-SEP-2016, integrated into UniProtKB/TrEMBL.
DT   07-SEP-2016, sequence version 1.
DT   05-FEB-2025, entry version 27.
DE   RecName: Full=XPG-I domain-containing protein {ECO:0000259|SMART:SM00484};
GN   ORFNames=AYL99_02353 {ECO:0000313|EMBL:OAP63126.1};
OS   Fonsecaea erecta.
OC   Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Eurotiomycetes;
OC   Chaetothyriomycetidae; Chaetothyriales; Herpotrichiellaceae; Fonsecaea.
OX   NCBI_TaxID=1367422 {ECO:0000313|EMBL:OAP63126.1, ECO:0000313|Proteomes:UP000078343};
RN   [1] {ECO:0000313|EMBL:OAP63126.1, ECO:0000313|Proteomes:UP000078343}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=CBS 125763 {ECO:0000313|EMBL:OAP63126.1,
RC   ECO:0000313|Proteomes:UP000078343};
RA   Weiss V.A., Vicente V.A., Raittz R.T., Moreno L.F., De Souza E.M.,
RA   Pedrosa F.O., Steffens M.B., Faoro H., Tadra-Sfeir M.Z., Najafzadeh M.J.,
RA   Felipe M.S., Teixeira M., Sun J., Xi L., Gomes R., De Azevedo C.M.,
RA   Salgado C.G., Da Silva M.B., Nascimento M.F., Queiroz-Telles F.,
RA   Attili D.S., Gorbushina A.;
RT   "Draft genome of Fonsecaea erecta CBS 125763.";
RL   Submitted (APR-2016) to the EMBL/GenBank/DDBJ databases.
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:OAP63126.1}.
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DR   EMBL; LVYI01000002; OAP63126.1; -; Genomic_DNA.
DR   RefSeq; XP_018696493.1; XM_018833869.1.
DR   AlphaFoldDB; A0A178ZUG4; -.
DR   STRING; 1367422.A0A178ZUG4; -.
DR   GeneID; 30006523; -.
DR   OrthoDB; 2959108at2759; -.
DR   Proteomes; UP000078343; Unassembled WGS sequence.
DR   GO; GO:0017108; F:5'-flap endonuclease activity; IEA:TreeGrafter.
DR   GO; GO:0006281; P:DNA repair; IEA:UniProtKB-ARBA.
DR   FunFam; 3.40.50.1010:FF:000037; Rad2-like endonuclease, putative (AFU_orthologue AFUA_3G13260); 1.
DR   Gene3D; 1.10.150.20; 5' to 3' exonuclease, C-terminal subdomain; 1.
DR   Gene3D; 3.40.50.1010; 5'-nuclease; 1.
DR   InterPro; IPR036279; 5-3_exonuclease_C_sf.
DR   InterPro; IPR041177; GEN1_C.
DR   InterPro; IPR029060; PIN-like_dom_sf.
DR   InterPro; IPR006086; XPG-I_dom.
DR   InterPro; IPR006084; XPG/Rad2.
DR   PANTHER; PTHR11081:SF75; ENDONUCLEASE, PUTATIVE (AFU_ORTHOLOGUE AFUA_3G13260)-RELATED; 1.
DR   PANTHER; PTHR11081; FLAP ENDONUCLEASE FAMILY MEMBER; 1.
DR   Pfam; PF18380; GEN1_C; 1.
DR   Pfam; PF00867; XPG_I; 1.
DR   PRINTS; PR00853; XPGRADSUPER.
DR   SMART; SM00484; XPGI; 1.
DR   SUPFAM; SSF47807; 5' to 3' exonuclease, C-terminal subdomain; 1.
DR   SUPFAM; SSF88723; PIN domain-like; 1.
PE   4: Predicted;
KW   Reference proteome {ECO:0000313|Proteomes:UP000078343}.
FT   DOMAIN          7..82
FT                   /note="XPG-I"
FT                   /evidence="ECO:0000259|SMART:SM00484"
FT   REGION          302..333
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          370..391
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          424..518
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          531..555
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        373..388
FT                   /note="Basic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        458..467
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        531..545
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   555 AA;  61655 MW;  62ED1CF748BF3BB7 CRC64;
     MSKGLISLFQ FPTHVAPGEA EAECAMLQRE GVVDAVMTQD VDALMFGSGL TLRDWSKEAN
     GKKGNKTPTH VSVLDLPRVK NMCGLDPEGM ILVALLSGGD YDEDGVAGIG CKLACEIARA
     GFGSDLVELV RNGDEDGITE WRERLQFELE TNESGYFKMK RKSVRIPDSF PNRKILGYYM
     NPAVTPVSEM ERLERKWAKT WDEEIDVQAL RDYAADMFEW LYKPGAWKFV RVMAPALLAD
     GLRRDRATSH LTSVDQITEQ RQHFVSDGIP ELRVTVVPAK VVGLNLDAEE DSPTYLQLLA
     EEENEGAEGE TEHAEIDENA PLSPSKKRKS PAWLPDAPEK MWIAQTIVEI GAREHVEQWK
     RIQFENANDP KKLATRKCPK KKESKKPKVI GGMQPGALLS YVVPADQSTE LEVSIAVPIK
     SPRRRAGANI SAPRRSKPKS SKLEEGYPPT MLGFFKSTKG SQPSHSTMPA RDAASYDLVK
     PGAGNDDDPL TLSNESRGDK HPRPSTSSPP ETGQRIGLHW IKAENFGNWD TGREAIRQPN
     ERNDANHLFA KPGRF
//