ID   A0A179U6U7_BLAGS        Unreviewed;       400 AA.
AC   A0A179U6U7;
DT   07-SEP-2016, integrated into UniProtKB/TrEMBL.
DT   07-SEP-2016, sequence version 1.
DT   02-APR-2025, entry version 24.
DE   RecName: Full=Pru domain-containing protein {ECO:0000259|PROSITE:PS51917};
GN   ORFNames=BDBG_00256 {ECO:0000313|EMBL:OAT03550.1};
OS   Blastomyces gilchristii (strain SLH14081) (Blastomyces dermatitidis).
OC   Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Eurotiomycetes;
OC   Eurotiomycetidae; Onygenales; Ajellomycetaceae; Blastomyces.
OX   NCBI_TaxID=559298 {ECO:0000313|EMBL:OAT03550.1, ECO:0000313|Proteomes:UP000002038};
RN   [1] {ECO:0000313|Proteomes:UP000002038}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=SLH14081 {ECO:0000313|Proteomes:UP000002038};
RX   PubMed=26439490; DOI=10.1371/journal.pgen.1005493;
RA   Munoz J.F., Gauthier G.M., Desjardins C.A., Gallo J.E., Holder J.,
RA   Sullivan T.D., Marty A.J., Carmen J.C., Chen Z., Ding L., Gujja S.,
RA   Magrini V., Misas E., Mitreva M., Priest M., Saif S., Whiston E.A.,
RA   Young S., Zeng Q., Goldman W.E., Mardis E.R., Taylor J.W., McEwen J.G.,
RA   Clay O.K., Klein B.S., Cuomo C.A.;
RT   "The dynamic genome and transcriptome of the human fungal pathogen
RT   Blastomyces and close relative Emmonsia.";
RL   PLoS Genet. 11:E1005493-E1005493(2015).
CC   -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000256|ARBA:ARBA00004496}.
CC       Nucleus {ECO:0000256|ARBA:ARBA00004123}.
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DR   EMBL; GG657448; OAT03550.1; -; Genomic_DNA.
DR   RefSeq; XP_002629010.1; XM_002628964.2.
DR   AlphaFoldDB; A0A179U6U7; -.
DR   STRING; 559298.A0A179U6U7; -.
DR   GeneID; 8510649; -.
DR   KEGG; bgh:BDBG_00256; -.
DR   VEuPathDB; FungiDB:BDBG_00256; -.
DR   OrthoDB; 340431at2759; -.
DR   Proteomes; UP000002038; Unassembled WGS sequence.
DR   GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR   GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR   GO; GO:0008541; C:proteasome regulatory particle, lid subcomplex; IEA:TreeGrafter.
DR   GO; GO:0061133; F:endopeptidase activator activity; IEA:TreeGrafter.
DR   GO; GO:0070628; F:proteasome binding; IEA:TreeGrafter.
DR   FunFam; 1.10.2020.20:FF:000004; WGS project CABT00000000 data, contig 2.6; 1.
DR   Gene3D; 1.10.2020.20; -; 1.
DR   Gene3D; 2.30.29.70; Proteasomal ubiquitin receptor Rpn13/ADRM1; 1.
DR   InterPro; IPR006773; Rpn13/ADRM1.
DR   InterPro; IPR044868; Rpn13/ADRM1_Pru.
DR   InterPro; IPR038633; Rpn13/ADRM1_Pru_sf.
DR   InterPro; IPR032368; RPN13_DEUBAD.
DR   InterPro; IPR038108; RPN13_DEUBAD_sf.
DR   PANTHER; PTHR12225; ADHESION REGULATING MOLECULE 1 110 KDA CELL MEMBRANE GLYCOPROTEIN; 1.
DR   PANTHER; PTHR12225:SF0; PROTEASOMAL UBIQUITIN RECEPTOR ADRM1; 1.
DR   Pfam; PF04683; Rpn13_ADRM1_Pru; 1.
DR   Pfam; PF16550; RPN13_C; 1.
DR   PROSITE; PS51917; PRU; 1.
PE   4: Predicted;
KW   Cytoplasm {ECO:0000256|ARBA:ARBA00022490};
KW   Nucleus {ECO:0000256|ARBA:ARBA00023242};
KW   Proteasome {ECO:0000256|ARBA:ARBA00022942};
KW   Reference proteome {ECO:0000313|Proteomes:UP000002038}.
FT   DOMAIN          1..140
FT                   /note="Pru"
FT                   /evidence="ECO:0000259|PROSITE:PS51917"
FT   REGION          150..223
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        161..171
FT                   /note="Acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        182..193
FT                   /note="Gly residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        195..207
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   400 AA;  42967 MW;  8A6CCAA85517B57C CRC64;
     MSIAPIITFK AGLCELDASV SPPRVKPQPA PGYIYLYSED DLVHFCWRRR SASLDEPELD
     LVMVPSDGTF TPYKLTSAEN PSNTDRPTNG RVYALKFSSS SQRHLFWLQS KSQHSNGNPA
     WFSARDLELG RIVNALLQGE DIDVRHAIAN IPGDNDGGNG GDDDETMEDV EGADHNPIHR
     AGGSGGAGPG ATGGDIREEG QESREGGADG GRAATASSDP SSVIQNLLRS LQQQGNQQSG
     SEAAEDPFTT LSELLPPSST LPFIESADSE TVDHLLSFLP TSLLLLAQSN LEIPSNMDPD
     SGPVKDALQA LTLEQKRDIL KRVLRSPQFT QSLGSLTVAL RDGGLPSISD ALKIPVENDG
     FMRRGGVPLG GGDAVRAFLE GVKRYVEEKE QDCQDKMETD
//