ID A0A179UAH3_BLAGS Unreviewed; 504 AA.
AC A0A179UAH3;
DT 07-SEP-2016, integrated into UniProtKB/TrEMBL.
DT 07-SEP-2016, sequence version 1.
DT 02-APR-2025, entry version 33.
DE RecName: Full=Adenylyl cyclase-associated protein {ECO:0000256|RuleBase:RU000647};
GN ORFNames=BDBG_00887 {ECO:0000313|EMBL:OAT04308.1};
OS Blastomyces gilchristii (strain SLH14081) (Blastomyces dermatitidis).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Eurotiomycetes;
OC Eurotiomycetidae; Onygenales; Ajellomycetaceae; Blastomyces.
OX NCBI_TaxID=559298 {ECO:0000313|EMBL:OAT04308.1, ECO:0000313|Proteomes:UP000002038};
RN [1] {ECO:0000313|Proteomes:UP000002038}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=SLH14081 {ECO:0000313|Proteomes:UP000002038};
RX PubMed=26439490; DOI=10.1371/journal.pgen.1005493;
RA Munoz J.F., Gauthier G.M., Desjardins C.A., Gallo J.E., Holder J.,
RA Sullivan T.D., Marty A.J., Carmen J.C., Chen Z., Ding L., Gujja S.,
RA Magrini V., Misas E., Mitreva M., Priest M., Saif S., Whiston E.A.,
RA Young S., Zeng Q., Goldman W.E., Mardis E.R., Taylor J.W., McEwen J.G.,
RA Clay O.K., Klein B.S., Cuomo C.A.;
RT "The dynamic genome and transcriptome of the human fungal pathogen
RT Blastomyces and close relative Emmonsia.";
RL PLoS Genet. 11:E1005493-E1005493(2015).
CC -!- SIMILARITY: Belongs to the CAP family. {ECO:0000256|ARBA:ARBA00007659,
CC ECO:0000256|RuleBase:RU000647}.
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DR EMBL; GG657449; OAT04308.1; -; Genomic_DNA.
DR RefSeq; XP_002627979.1; XM_002627933.1.
DR AlphaFoldDB; A0A179UAH3; -.
DR STRING; 559298.A0A179UAH3; -.
DR GeneID; 8507298; -.
DR KEGG; bgh:BDBG_00887; -.
DR VEuPathDB; FungiDB:BDBG_00887; -.
DR OrthoDB; 77251at2759; -.
DR Proteomes; UP000002038; Unassembled WGS sequence.
DR GO; GO:0005737; C:cytoplasm; IEA:TreeGrafter.
DR GO; GO:0003779; F:actin binding; IEA:InterPro.
DR GO; GO:0008179; F:adenylate cyclase binding; IEA:TreeGrafter.
DR GO; GO:0007015; P:actin filament organization; IEA:TreeGrafter.
DR GO; GO:0019933; P:cAMP-mediated signaling; IEA:TreeGrafter.
DR FunFam; 2.160.20.70:FF:000008; Adenylyl cyclase-associated protein; 1.
DR Gene3D; 2.160.20.70; -; 1.
DR Gene3D; 1.25.40.330; Adenylate cyclase-associated CAP, N-terminal domain; 1.
DR InterPro; IPR001837; Adenylate_cyclase-assoc_CAP.
DR InterPro; IPR013912; Adenylate_cyclase-assoc_CAP_C.
DR InterPro; IPR013992; Adenylate_cyclase-assoc_CAP_N.
DR InterPro; IPR017901; C-CAP_CF_C-like.
DR InterPro; IPR016098; CAP/MinC_C.
DR InterPro; IPR036223; CAP_C_sf.
DR InterPro; IPR018106; CAP_CS_N.
DR InterPro; IPR053950; CAP_N.
DR InterPro; IPR036222; CAP_N_sf.
DR InterPro; IPR006599; CARP_motif.
DR PANTHER; PTHR10652; ADENYLYL CYCLASE-ASSOCIATED PROTEIN; 1.
DR PANTHER; PTHR10652:SF0; ADENYLYL CYCLASE-ASSOCIATED PROTEIN; 1.
DR Pfam; PF08603; CAP_C; 1.
DR Pfam; PF21938; CAP_N; 1.
DR Pfam; PF01213; CAP_N-CM; 1.
DR SMART; SM00673; CARP; 2.
DR SUPFAM; SSF69340; C-terminal domain of adenylylcyclase associated protein; 1.
DR SUPFAM; SSF101278; N-terminal domain of adenylylcyclase associated protein, CAP; 1.
DR PROSITE; PS51329; C_CAP_COFACTOR_C; 1.
DR PROSITE; PS01088; CAP_1; 1.
PE 3: Inferred from homology;
KW Reference proteome {ECO:0000313|Proteomes:UP000002038}.
FT DOMAIN 345..482
FT /note="C-CAP/cofactor C-like"
FT /evidence="ECO:0000259|PROSITE:PS51329"
FT REGION 26..71
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 207..271
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 284..348
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 44..57
FT /note="Low complexity"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 58..71
FT /note="Pro residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 235..257
FT /note="Pro residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 258..267
FT /note="Low complexity"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 289..298
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 504 AA; 53856 MW; 9A94ABCDE88BE172 CRC64;
MTTNQMNNFT TLIKRLEAAT SRLEDMATSL EGSGPGSPAA DGIATSTASV SSKTASSPLP
PPPPVVEPPP RQIEDFDALI NKEVKNFVEL SEKLGEPAGE QSKAILRAFQ AERTYLYIAL
KAKKPDQQSP DLLSDLRKAS DEINNIREAN RPSPLFNHLS AVAEGVVSLG WFFEPRPAEF
VRESVAGAQF YGDRVLREYK GKALSEWPDM EQPGWSRRNG GPETAPIRFT DASAFPPPPP
PPAAGAGGPP PPPPPPASVA APPKAAPTGD MSSVFEQLNQ GSAVTSGLRK VDKSEMTHKN
PGLRAGSLVP ERADSRTGVT SPTSRGKSPV PSKKPKPESM RAKKPSRKQL DGNKWYIEHY
DSPSDIIEIP AQLSHSILIS HCNKAIVKIN GKANAISIDN CTGLSVIVDS LVSSVDVIKS
PKFALQIDGV VPTILLDQVD GASLYLSQES LNTEVFSSKS SNVNIVVPPK EGTDDDSKEL
PVPEQIRTVI KNGAAVSEIV EHAG
//
