ID A0A194AKQ0_9BACT Unreviewed; 634 AA.
AC A0A194AKQ0;
DT 05-OCT-2016, integrated into UniProtKB/TrEMBL.
DT 05-OCT-2016, sequence version 1.
DT 28-JAN-2026, entry version 41.
DE RecName: Full=Selenocysteine-specific elongation factor {ECO:0000256|ARBA:ARBA00015953};
DE AltName: Full=SelB translation factor {ECO:0000256|ARBA:ARBA00031615};
GN ORFNames=DPF_2006 {ECO:0000313|EMBL:GAU09284.1};
OS Desulfoplanes formicivorans.
OC Bacteria; Pseudomonadati; Thermodesulfobacteriota; Desulfovibrionia;
OC Desulfovibrionales; Desulfoplanaceae; Desulfoplanes.
OX NCBI_TaxID=1592317 {ECO:0000313|EMBL:GAU09284.1, ECO:0000313|Proteomes:UP000095200};
RN [1] {ECO:0000313|Proteomes:UP000095200}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Pf12B {ECO:0000313|Proteomes:UP000095200};
RA Watanabe M., Kojima H., Fukui M.;
RT "Draft genome sequence of Desulfoplanes formicivorans strain Pf12B.";
RL Submitted (JUN-2016) to the EMBL/GenBank/DDBJ databases.
CC -!- FUNCTION: Translation factor necessary for the incorporation of
CC selenocysteine into proteins. It probably replaces EF-Tu for the
CC insertion of selenocysteine directed by the UGA codon. SelB binds GTP
CC and GDP. {ECO:0000256|ARBA:ARBA00025526}.
CC -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000256|ARBA:ARBA00004496}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:GAU09284.1}.
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DR EMBL; BDFE01000017; GAU09284.1; -; Genomic_DNA.
DR RefSeq; WP_069859539.1; NZ_BDFE01000017.1.
DR AlphaFoldDB; A0A194AKQ0; -.
DR STRING; 1592317.DPF_2006; -.
DR OrthoDB; 9803139at2; -.
DR Proteomes; UP000095200; Unassembled WGS sequence.
DR GO; GO:0005829; C:cytosol; IEA:TreeGrafter.
DR GO; GO:0005525; F:GTP binding; IEA:UniProtKB-KW.
DR GO; GO:0003924; F:GTPase activity; IEA:InterPro.
DR GO; GO:0003723; F:RNA binding; IEA:InterPro.
DR GO; GO:0003746; F:translation elongation factor activity; IEA:UniProtKB-KW.
DR GO; GO:0001514; P:selenocysteine incorporation; IEA:InterPro.
DR CDD; cd04171; SelB; 1.
DR CDD; cd03696; SelB_II; 1.
DR CDD; cd15491; selB_III; 1.
DR FunFam; 3.40.50.300:FF:001064; Selenocysteine-specific translation elongation factor; 1.
DR Gene3D; 1.10.10.2770; -; 1.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 1.
DR Gene3D; 2.40.30.10; Translation factors; 1.
DR Gene3D; 1.10.10.10; Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain; 1.
DR InterPro; IPR057335; Beta-barrel_SelB.
DR InterPro; IPR050055; EF-Tu_GTPase.
DR InterPro; IPR004161; EFTu-like_2.
DR InterPro; IPR015190; Elong_fac_SelB-wing-hlx_typ-2.
DR InterPro; IPR031157; G_TR_CS.
DR InterPro; IPR027417; P-loop_NTPase.
DR InterPro; IPR015191; SelB_WHD4.
DR InterPro; IPR005225; Small_GTP-bd.
DR InterPro; IPR000795; T_Tr_GTP-bd_dom.
DR InterPro; IPR009000; Transl_B-barrel_sf.
DR InterPro; IPR009001; Transl_elong_EF1A/Init_IF2_C.
DR InterPro; IPR004535; Transl_elong_SelB.
DR InterPro; IPR036388; WH-like_DNA-bd_sf.
DR InterPro; IPR036390; WH_DNA-bd_sf.
DR NCBIfam; TIGR00475; selB; 1.
DR NCBIfam; TIGR00231; small_GTP; 1.
DR PANTHER; PTHR43721:SF22; ELONGATION FACTOR TU, MITOCHONDRIAL; 1.
DR PANTHER; PTHR43721; ELONGATION FACTOR TU-RELATED; 1.
DR Pfam; PF25461; Beta-barrel_SelB; 1.
DR Pfam; PF00009; GTP_EFTU; 1.
DR Pfam; PF03144; GTP_EFTU_D2; 1.
DR Pfam; PF09106; WHD_2nd_SelB; 1.
DR Pfam; PF09107; WHD_3rd_SelB; 1.
DR PRINTS; PR00315; ELONGATNFCT.
DR SUPFAM; SSF50465; EF-Tu/eEF-1alpha/eIF2-gamma C-terminal domain; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR SUPFAM; SSF50447; Translation proteins; 1.
DR SUPFAM; SSF46785; Winged helix' DNA-binding domain; 3.
DR PROSITE; PS00301; G_TR_1; 1.
DR PROSITE; PS51722; G_TR_2; 1.
PE 4: Predicted;
KW Cytoplasm {ECO:0000256|ARBA:ARBA00022490};
KW Elongation factor {ECO:0000313|EMBL:GAU09284.1};
KW GTP-binding {ECO:0000256|ARBA:ARBA00023134};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741};
KW Protein biosynthesis {ECO:0000256|ARBA:ARBA00022917};
KW Reference proteome {ECO:0000313|Proteomes:UP000095200}.
FT DOMAIN 1..173
FT /note="Tr-type G"
FT /evidence="ECO:0000259|PROSITE:PS51722"
SQ SEQUENCE 634 AA; 70983 MW; 4297516D5EC1BDD6 CRC64;
MPVIMGTAGH IDHGKTTLIK ALTGINCDRL VEEKKRGITI ELGFAFLDLD TDLRLGIIDV
PGHEKFVKNM VAGAAGIDFA LLVIAADEGV MPQTREHLEI CTLLGIKTGL VALTKTDMVD
EEWLELVTED VASYLESTFL KDAPIIPVSA HTGASIDELK QEITRLTRAF KPKRRSDLFR
LPIDRVFVMK GYGTVVTGTS FSGKLKVGQD LVLYPSGLTT KVRGLQVHGD SQEEAEAGLR
TAINLYGLEK AEISRGEMLA QPDSLFPSTV WDLEITCLPS AKKGIKHRTQ VHFHHGTREI
LARLYFLDRD NLEPGETAVC QVRFETPMVG VYGDRCIIRS FSPLQTIAGA SIINPLGRKV
KRFSRDLHIL ETLASAQEKD LVIHQLELAG TGGLSFAKLR IMTDIESKAL EKVLQTLGGR
QQAFLVDKDQ RIYVSGELVL ELCDQAIAFF KTFHRENPMR PGLSRGELAS TWGKDLSPKL
FHFVLERLNK QERIVVDQEL LHLPGHKVSL ASDQDKLRRE LTALYQKGGL TPPTLKVVQE
TLDVSAKDIL PLMRHLVEEN QLIKISEDLY FDARAIQELR TVLTDFFATR EELTPADFKD
LTGLSRKFAI PLLEFMDKQK FTVRIGNSRK MRRQ
//
