ID A0A195BYR0_9HYME Unreviewed; 210 AA.
AC A0A195BYR0;
DT 05-OCT-2016, integrated into UniProtKB/TrEMBL.
DT 05-OCT-2016, sequence version 1.
DT 18-JUN-2025, entry version 32.
DE RecName: Full=DNA-directed RNA polymerases I, II, and III subunit RPABC1 {ECO:0000256|ARBA:ARBA00020809};
DE AltName: Full=RPB5 homolog {ECO:0000256|ARBA:ARBA00032836};
GN ORFNames=ALC62_15808 {ECO:0000313|EMBL:KYM93450.1};
OS Cyphomyrmex costatus.
OC Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota;
OC Neoptera; Endopterygota; Hymenoptera; Apocrita; Aculeata; Formicoidea;
OC Formicidae; Myrmicinae; Cyphomyrmex.
OX NCBI_TaxID=456900 {ECO:0000313|EMBL:KYM93450.1, ECO:0000313|Proteomes:UP000078542};
RN [1] {ECO:0000313|EMBL:KYM93450.1, ECO:0000313|Proteomes:UP000078542}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=MS0001 {ECO:0000313|EMBL:KYM93450.1};
RC TISSUE=Whole body {ECO:0000313|EMBL:KYM93450.1};
RA Nygaard S., Hu H., Boomsma J., Zhang G.;
RT "Cyphomyrmex costatus WGS genome.";
RL Submitted (MAR-2016) to the EMBL/GenBank/DDBJ databases.
CC -!- FUNCTION: DNA-dependent RNA polymerase catalyzes the transcription of
CC DNA into RNA using the four ribonucleoside triphosphates as substrates.
CC Common component of RNA polymerases I, II and III which synthesize
CC ribosomal RNA precursors, mRNA precursors and many functional non-
CC coding RNAs, and small RNAs, such as 5S rRNA and tRNAs, respectively.
CC Pol II is the central component of the basal RNA polymerase II
CC transcription machinery. Pols are composed of mobile elements that move
CC relative to each other. In Pol II, RPB5 is part of the lower jaw
CC surrounding the central large cleft and thought to grab the incoming
CC DNA template. Seems to be the major component in this process.
CC {ECO:0000256|ARBA:ARBA00060082}.
CC -!- SUBUNIT: Component of the RNA polymerase I (Pol I), RNA polymerase II
CC (Pol II) and RNA polymerase III (Pol III) complexes consisting of at
CC least 13, 12 and 17 subunits, respectively. In RNA Pol II, this subunit
CC is present in 2-fold molar excess over the other subunits.
CC {ECO:0000256|ARBA:ARBA00064429}.
CC -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000256|ARBA:ARBA00004123}.
CC -!- SIMILARITY: Belongs to the archaeal Rpo5/eukaryotic RPB5 RNA polymerase
CC subunit family. {ECO:0000256|ARBA:ARBA00025765}.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; KQ978501; KYM93450.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A195BYR0; -.
DR STRING; 456900.A0A195BYR0; -.
DR CTD; 136034817; -.
DR OrthoDB; 248779at2759; -.
DR Proteomes; UP000078542; Unassembled WGS sequence.
DR GO; GO:0005736; C:RNA polymerase I complex; IEA:TreeGrafter.
DR GO; GO:0005665; C:RNA polymerase II, core complex; IEA:TreeGrafter.
DR GO; GO:0005666; C:RNA polymerase III complex; IEA:TreeGrafter.
DR GO; GO:0003677; F:DNA binding; IEA:InterPro.
DR GO; GO:0003899; F:DNA-directed RNA polymerase activity; IEA:InterPro.
DR GO; GO:0006366; P:transcription by RNA polymerase II; IEA:TreeGrafter.
DR GO; GO:0006362; P:transcription elongation by RNA polymerase I; IEA:TreeGrafter.
DR GO; GO:0042797; P:tRNA transcription by RNA polymerase III; IEA:TreeGrafter.
DR FunFam; 3.40.1340.10:FF:000001; DNA-directed RNA polymerases I, II, and III subunit RPABC1; 1.
DR FunFam; 3.90.940.20:FF:000001; DNA-directed RNA polymerases I, II, and III subunit RPABC1; 1.
DR Gene3D; 3.40.1340.10; RNA polymerase, Rpb5, N-terminal domain; 1.
DR Gene3D; 3.90.940.20; RPB5-like RNA polymerase subunit; 1.
DR HAMAP; MF_00025; RNApol_Rpo5_RPB5; 1.
DR InterPro; IPR014381; Arch_Rpo5/euc_Rpb5.
DR InterPro; IPR005571; RNA_pol_Rpb5_N.
DR InterPro; IPR036710; RNA_pol_Rpb5_N_sf.
DR InterPro; IPR000783; RNA_pol_subH/Rpb5_C.
DR InterPro; IPR020608; RNA_pol_subH/Rpb5_CS.
DR InterPro; IPR035913; RPB5-like_sf.
DR NCBIfam; NF007129; PRK09570.1; 1.
DR PANTHER; PTHR10535; DNA-DIRECTED RNA POLYMERASES I, II, AND III SUBUNIT RPABC1; 1.
DR PANTHER; PTHR10535:SF0; DNA-DIRECTED RNA POLYMERASES I, II, AND III SUBUNIT RPABC1; 1.
DR Pfam; PF01191; RNA_pol_Rpb5_C; 1.
DR Pfam; PF03871; RNA_pol_Rpb5_N; 1.
DR PIRSF; PIRSF000747; RPB5; 1.
DR SUPFAM; SSF53036; Eukaryotic RPB5 N-terminal domain; 1.
DR SUPFAM; SSF55287; RPB5-like RNA polymerase subunit; 1.
DR PROSITE; PS01110; RNA_POL_H_23KD; 1.
PE 3: Inferred from homology;
KW DNA-directed RNA polymerase {ECO:0000256|ARBA:ARBA00022478,
KW ECO:0000313|EMBL:KYM93450.1}; Nucleus {ECO:0000256|ARBA:ARBA00023242};
KW Reference proteome {ECO:0000313|Proteomes:UP000078542};
KW Transcription {ECO:0000256|ARBA:ARBA00023163}.
FT DOMAIN 4..94
FT /note="RNA polymerase Rpb5 N-terminal"
FT /evidence="ECO:0000259|Pfam:PF03871"
FT DOMAIN 137..209
FT /note="RNA polymerase subunit H/Rpb5 C-terminal"
FT /evidence="ECO:0000259|Pfam:PF01191"
SQ SEQUENCE 210 AA; 24608 MW; 1D4AEDDBC7B8BEB2 CRC64;
MDDEDETYKL WRIRKTVMQL CHDRGYLVTQ DELDQTLELF KEQFGDKPSE KRPARSDLIV
LVAHNDDPTD QLFVFFPDEP KIGIKTIKTY CQRMQEEKIH RAIIVVQQGM TPSAKQSLVD
MAPKYILEQF LESELLINIT EHELVPEHIV LTPDEKEELL TRYKLKENQL MRIQAGDPVA
RYFGLKRGQV VKIIRPSETA GRYISYRLVC
//
