ID A0A1A6GL06_NEOLE Unreviewed; 390 AA.
AC A0A1A6GL06;
DT 05-OCT-2016, integrated into UniProtKB/TrEMBL.
DT 05-OCT-2016, sequence version 1.
DT 02-APR-2025, entry version 31.
DE RecName: Full=SOCS box domain-containing protein {ECO:0000259|PROSITE:PS50225};
GN ORFNames=A6R68_04565 {ECO:0000313|EMBL:OBS66891.1};
OS Neotoma lepida (Desert woodrat).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea;
OC Cricetidae; Neotominae; Neotoma.
OX NCBI_TaxID=56216 {ECO:0000313|EMBL:OBS66891.1, ECO:0000313|Proteomes:UP000092124};
RN [1] {ECO:0000313|EMBL:OBS66891.1, ECO:0000313|Proteomes:UP000092124}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=417 {ECO:0000313|EMBL:OBS66891.1};
RC TISSUE=Liver {ECO:0000313|EMBL:OBS66891.1};
RA Campbell M., Oakeson K.F., Yandell M., Halpert J.R., Dearing D.;
RT "The Draft Genome Sequence and Annotation of the Desert Woodrat Neotoma
RT lepida.";
RL Submitted (JUN-2016) to the EMBL/GenBank/DDBJ databases.
CC -!- PATHWAY: Protein modification; protein ubiquitination.
CC {ECO:0000256|ARBA:ARBA00004906}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:OBS66891.1}.
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DR EMBL; LZPO01087171; OBS66891.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A1A6GL06; -.
DR STRING; 56216.A0A1A6GL06; -.
DR OrthoDB; 8820570at2759; -.
DR UniPathway; UPA00143; -.
DR Proteomes; UP000092124; Unassembled WGS sequence.
DR GO; GO:0005942; C:phosphatidylinositol 3-kinase complex; IEA:TreeGrafter.
DR GO; GO:0046935; F:1-phosphatidylinositol-3-kinase regulator activity; IEA:TreeGrafter.
DR GO; GO:0035556; P:intracellular signal transduction; IEA:InterPro.
DR GO; GO:0046854; P:phosphatidylinositol phosphate biosynthetic process; IEA:TreeGrafter.
DR GO; GO:0016567; P:protein ubiquitination; IEA:UniProtKB-UniPathway.
DR Gene3D; 1.10.750.20; SOCS box; 1.
DR InterPro; IPR022252; SOCS4/SOCS5_dom.
DR InterPro; IPR001496; SOCS_box.
DR InterPro; IPR036036; SOCS_box-like_dom_sf.
DR PANTHER; PTHR10155; PHOSPHATIDYLINOSITOL 3-KINASE REGULATORY SUBUNIT; 1.
DR PANTHER; PTHR10155:SF15; SUPPRESSOR OF CYTOKINE SIGNALING 5; 1.
DR Pfam; PF12610; SOCS; 1.
DR Pfam; PF07525; SOCS_box; 1.
DR SMART; SM00253; SOCS; 1.
DR SMART; SM00969; SOCS_box; 1.
DR SUPFAM; SSF158235; SOCS box-like; 1.
DR PROSITE; PS50225; SOCS; 1.
PE 4: Predicted;
KW Reference proteome {ECO:0000313|Proteomes:UP000092124};
KW SH2 domain {ECO:0000256|ARBA:ARBA00022999}.
FT DOMAIN 310..344
FT /note="SOCS box"
FT /evidence="ECO:0000259|PROSITE:PS50225"
FT REGION 37..56
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 93..187
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 154..165
FT /note="Low complexity"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 390 AA; 43870 MW; 89722D492329AD96 CRC64;
MALWCWGLGI RVAEADHEGG SRSESVDMNS SRCLSVKEKS ASLGEAAPQQ QSSPLRENVA
LQLGLSPSKT FSRRNQNCAA EIPQVVEISI EKDSDSCATP GTRLARRDSY SRHAPWGGKK
KHSCSTKTQS SLDTEKKFGR TRSGLQRRER RYGVSSVHDM DSVSSRAVGS RSLRQRLQDT
VEDEEDRLRE RRRLSIEEGV DPPPNAQIHT FEATAQVNPL YKLGPKLAPG MTEISGDGSA
VPQTNCDSEE DSTTLCLQSR RQKQRQVSGD SHSHEDYLFS VSFRRYNRSL HARIEQWNHN
FSFDAHDPCY ICRAVICRCT TYDGIGGLPL PSVLQDFLKE YHYKQKVRVR WLEREPVKAK
IPSVKPVLKG FPSKSELDVK SLPLNNPSRL
//
