ID A0A1A7ZCV5_NOTFU Unreviewed; 432 AA.
AC A0A1A7ZCV5;
DT 05-OCT-2016, integrated into UniProtKB/TrEMBL.
DT 05-OCT-2016, sequence version 1.
DT 28-JAN-2026, entry version 38.
DE RecName: Full=NAD(+) kinase {ECO:0000256|ARBA:ARBA00012120};
DE EC=2.7.1.23 {ECO:0000256|ARBA:ARBA00012120};
GN Name=NADKA {ECO:0000313|EMBL:SBP40637.1};
GN Synonyms=NADK {ECO:0000313|Ensembl:ENSNFUP00015018202.1}, nadk
GN {ECO:0000313|EMBL:KAF7209063.1};
GN ORFNames=G4P62_013968 {ECO:0000313|EMBL:KAF7209063.1};
OS Nothobranchius furzeri (Turquoise killifish).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata;
OC Ovalentaria; Atherinomorphae; Cyprinodontiformes; Nothobranchiidae;
OC Nothobranchius.
OX NCBI_TaxID=105023 {ECO:0000313|EMBL:SBP40637.1};
RN [1] {ECO:0000313|Ensembl:ENSNFUP00015018202.1}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=GRZ {ECO:0000313|Ensembl:ENSNFUP00015018202.1};
RA Senf B., Petzold A., Downie B.R., Koch P., Platzer M.;
RL Submitted (AUG-2014) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|EMBL:SBP40637.1}
RP NUCLEOTIDE SEQUENCE.
RC TISSUE=Brain {ECO:0000313|EMBL:SBP40637.1};
RA Lavstsen T., Jespersen J.S.;
RL Submitted (MAY-2016) to the EMBL/GenBank/DDBJ databases.
RN [3] {ECO:0000313|EMBL:SBP40637.1}
RP NUCLEOTIDE SEQUENCE.
RC TISSUE=Brain {ECO:0000313|EMBL:SBP40637.1};
RA Reichwald K., Felder M., Petzold A., Koch P., Groth M., Platzer M.;
RT "The genome of a short-lived fish provides insights into sex chromosome
RT evolution and the genetic control of aging.";
RL Submitted (JUN-2016) to the EMBL/GenBank/DDBJ databases.
RN [4] {ECO:0000313|EMBL:KAF7209063.1}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=GRZ {ECO:0000313|EMBL:KAF7209063.1};
RC TISSUE=Whole {ECO:0000313|EMBL:KAF7209063.1};
RA Willemsen D., Cui R., Valenzano D.R.;
RT "Intra-Species Differences in Population Size shape Life History and Genome
RT Evolution.";
RL Submitted (MAR-2020) to the EMBL/GenBank/DDBJ databases.
RN [5] {ECO:0000313|Ensembl:ENSNFUP00015018202.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (MAY-2025) to UniProtKB.
CC -!- SIMILARITY: Belongs to the NAD kinase family.
CC {ECO:0000256|ARBA:ARBA00010995}.
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DR EMBL; JAAVVJ010000013; KAF7209063.1; -; Genomic_DNA.
DR EMBL; HADY01002152; SBP40637.1; -; Transcribed_RNA.
DR EMBL; HAEJ01017755; SBS58212.1; -; Transcribed_RNA.
DR RefSeq; XP_015822450.1; XM_015966964.3.
DR AlphaFoldDB; A0A1A7ZCV5; -.
DR Ensembl; ENSNFUT00015019028.1; ENSNFUP00015018202.1; ENSNFUG00015008249.1.
DR GeneID; 107390331; -.
DR KEGG; nfu:107390331; -.
DR CTD; 550242; -.
DR GeneTree; ENSGT00390000013792; -.
DR OMA; CVYLMEA; -.
DR OrthoDB; 24581at2759; -.
DR Proteomes; UP000694548; Chromosome sgr15.
DR Proteomes; UP000822369; Chromosome 13.
DR Bgee; ENSNFUG00015008249; Expressed in caudal fin and 3 other cell types or tissues.
DR GO; GO:0003951; F:NAD+ kinase activity; IEA:UniProtKB-EC.
DR GO; GO:0019674; P:NAD+ metabolic process; IEA:InterPro.
DR GO; GO:0006741; P:NADP+ biosynthetic process; IEA:InterPro.
DR FunFam; 2.60.200.30:FF:000003; NAD kinase b; 1.
DR Gene3D; 3.40.50.10330; Probable inorganic polyphosphate/atp-NAD kinase, domain 1; 1.
DR Gene3D; 2.60.200.30; Probable inorganic polyphosphate/atp-NAD kinase, domain 2; 1.
DR HAMAP; MF_00361; NAD_kinase; 1.
DR InterPro; IPR017438; ATP-NAD_kinase_N.
DR InterPro; IPR017437; ATP-NAD_kinase_PpnK-typ_C.
DR InterPro; IPR016064; NAD/diacylglycerol_kinase_sf.
DR InterPro; IPR002504; NADK.
DR PANTHER; PTHR20275; NAD KINASE; 1.
DR PANTHER; PTHR20275:SF30; NAD(+) KINASE; 1.
DR Pfam; PF01513; NAD_kinase; 1.
DR Pfam; PF20143; NAD_kinase_C; 1.
DR SUPFAM; SSF111331; NAD kinase/diacylglycerol kinase-like; 1.
PE 3: Inferred from homology;
KW Kinase {ECO:0000256|ARBA:ARBA00022777, ECO:0000313|EMBL:SBP40637.1};
KW NAD {ECO:0000256|ARBA:ARBA00023027}; NADP {ECO:0000256|ARBA:ARBA00022857};
KW Reference proteome {ECO:0000313|Proteomes:UP000694548};
KW Transferase {ECO:0000256|ARBA:ARBA00022679}.
SQ SEQUENCE 432 AA; 47828 MW; 875158E2BF40647D CRC64;
MDGGPEVRKE AAPYCCATCE GGGEVPGLSV ARRYTKSRSL SASSASSYSE YRRNQSLHGP
SPVTTFGPKA CMLQNPHAVM HIQDPASQKL TWNKPPKSVL VIKKIRDASL LQPFKELCIF
LTEVKNMIVY VEKKVLDDPA ISGDENFGAI AKKFCTFRED FDDLSNRVDF IICLGGDGTL
LYASSLFQES VPPVMAFHLG SLGFLTPFKF DTYQSQVTQI IEGNAAIVLR SRLKVQVLKE
NWEKKDTMDE KSIILTNGDA ESSRKVMQYQ VLNEVVVDRG PSSYLSNVDL YLDGHLITTV
QGDGVIVSTP TGSTAYAVAA GASMIHPNVP AIMITPICPH SLSFRPIVVP AGVELKIKLS
REARNTAWVS FDGRKRQEIC HGDSITITTS CFPVPSICFR DPVNDWFESL AQCLHWNVRK
KQNYLISEDE EF
//
