ID A0A1A8US73_NOTFU Unreviewed; 234 AA.
AC A0A1A8US73;
DT 05-OCT-2016, integrated into UniProtKB/TrEMBL.
DT 05-OCT-2016, sequence version 1.
DT 28-JAN-2026, entry version 30.
DE SubName: Full=RPA interacting protein {ECO:0000313|EMBL:SBS51209.1, ECO:0000313|Ensembl:ENSNFUP00015004182.1};
DE SubName: Full=Transcript variant X4 {ECO:0000313|EMBL:KAF7220605.1};
GN Name=RPAIN {ECO:0000313|EMBL:SBS51209.1};
GN Synonyms=rpain {ECO:0000313|EMBL:KAF7220605.1,
GN ECO:0000313|Ensembl:ENSNFUP00015004182.1};
GN ORFNames=G4P62_003204 {ECO:0000313|EMBL:KAF7220605.1};
OS Nothobranchius furzeri (Turquoise killifish).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata;
OC Ovalentaria; Atherinomorphae; Cyprinodontiformes; Nothobranchiidae;
OC Nothobranchius.
OX NCBI_TaxID=105023 {ECO:0000313|EMBL:SBS51209.1};
RN [1] {ECO:0000313|Ensembl:ENSNFUP00015004182.1}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=GRZ {ECO:0000313|Ensembl:ENSNFUP00015004182.1};
RA Senf B., Petzold A., Downie B.R., Koch P., Platzer M.;
RL Submitted (AUG-2014) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|EMBL:SBS51209.1}
RP NUCLEOTIDE SEQUENCE.
RC TISSUE=Brain {ECO:0000313|EMBL:SBS51209.1};
RA Lavstsen T., Jespersen J.S.;
RL Submitted (MAY-2016) to the EMBL/GenBank/DDBJ databases.
RN [3] {ECO:0000313|EMBL:SBS51209.1}
RP NUCLEOTIDE SEQUENCE.
RC TISSUE=Brain {ECO:0000313|EMBL:SBS51209.1};
RA Reichwald K., Felder M., Petzold A., Koch P., Groth M., Platzer M.;
RT "The genome of a short-lived fish provides insights into sex chromosome
RT evolution and the genetic control of aging.";
RL Submitted (JUN-2016) to the EMBL/GenBank/DDBJ databases.
RN [4] {ECO:0000313|EMBL:KAF7220605.1}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=GRZ {ECO:0000313|EMBL:KAF7220605.1};
RC TISSUE=Whole {ECO:0000313|EMBL:KAF7220605.1};
RA Willemsen D., Cui R., Valenzano D.R.;
RT "Intra-Species Differences in Population Size shape Life History and Genome
RT Evolution.";
RL Submitted (MAR-2020) to the EMBL/GenBank/DDBJ databases.
RN [5] {ECO:0000313|Ensembl:ENSNFUP00015004182.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (MAY-2025) to UniProtKB.
CC -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000256|ARBA:ARBA00004123}.
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DR EMBL; JAAVVJ010000006; KAF7220605.1; -; Genomic_DNA.
DR EMBL; HADY01012606; SBP51091.1; -; Transcribed_RNA.
DR EMBL; HAEJ01010752; SBS51209.1; -; Transcribed_RNA.
DR RefSeq; XP_015800685.1; XM_015945199.3.
DR AlphaFoldDB; A0A1A8US73; -.
DR Ensembl; ENSNFUT00015004420.1; ENSNFUP00015004182.1; ENSNFUG00015002100.1.
DR GeneID; 107376211; -.
DR CTD; 84268; -.
DR GeneTree; ENSGT00390000006416; -.
DR OMA; ACDSWTV; -.
DR OrthoDB; 435311at2759; -.
DR Proteomes; UP000694548; Chromosome sgr03.
DR Proteomes; UP000822369; Chromosome 6.
DR Bgee; ENSNFUG00015002100; Expressed in liver and 3 other cell types or tissues.
DR GO; GO:0016605; C:PML body; IEA:TreeGrafter.
DR GO; GO:0008270; F:zinc ion binding; IEA:UniProtKB-KW.
DR GO; GO:0006606; P:protein import into nucleus; IEA:TreeGrafter.
DR InterPro; IPR028156; RIP.
DR InterPro; IPR028159; RPA_interact_C_dom.
DR InterPro; IPR028155; RPA_interact_central.
DR InterPro; IPR028158; RPA_interact_N_dom.
DR PANTHER; PTHR31742:SF1; RPA-INTERACTING PROTEIN; 1.
DR PANTHER; PTHR31742; RPA-INTERACTING PROTEIN RPAIN; 1.
DR Pfam; PF14768; RPA_interact_C; 1.
DR Pfam; PF14767; RPA_interact_M; 1.
DR Pfam; PF14766; RPA_interact_N; 1.
PE 4: Predicted;
KW Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW Nucleus {ECO:0000256|ARBA:ARBA00023242};
KW Reference proteome {ECO:0000313|Proteomes:UP000694548};
KW Zinc {ECO:0000256|ARBA:ARBA00022833};
KW Zinc-finger {ECO:0000256|ARBA:ARBA00022771}.
FT DOMAIN 20..57
FT /note="RPA-interacting protein N-terminal"
FT /evidence="ECO:0000259|Pfam:PF14766"
FT DOMAIN 65..143
FT /note="RPA-interacting protein central"
FT /evidence="ECO:0000259|Pfam:PF14767"
FT DOMAIN 152..231
FT /note="RPA-interacting protein C-terminal"
FT /evidence="ECO:0000259|Pfam:PF14768"
SQ SEQUENCE 234 AA; 26945 MW; EA479C8BFE49006C CRC64;
MLKCDVSEAV LTSLMDAQLR HRLLYKRSTP PWREVFRRRC VDRLKNSRSR LVDRYRQRST
AGALSIVDEV MEEEWTALQA EDRRLLSLRG PRNMQEVGGV VQEYDELAVL DEIQQELMSH
EISIIQEYER NLQLEQQYLS SVVEDMEHMH VICPICHTNN LSINSCFVSC PCGLHISTKR
SVTPDVLQHL LESRVSEHRE TCLQSPVFSI APGAERSPGL FISCKVCDYL SVVL
//
