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Database: UniProt
Entry: A0A1A8X0S9_PLAMA
LinkDB: A0A1A8X0S9_PLAMA
Original site: A0A1A8X0S9_PLAMA 
ID   A0A1A8X0S9_PLAMA        Unreviewed;       405 AA.
AC   A0A1A8X0S9;
DT   05-OCT-2016, integrated into UniProtKB/TrEMBL.
DT   05-OCT-2016, sequence version 1.
DT   02-JUN-2021, entry version 34.
DE   RecName: Full=S-antigen protein {ECO:0000256|ARBA:ARBA00015853};
GN   Name=PmUG01_10046600 {ECO:0000313|EMBL:SCN45228.1};
GN   ORFNames=PMALA_061350 {ECO:0000313|EMBL:SBS97769.1}, PMUG01_10046600
GN   {ECO:0000313|EMBL:SCN45228.1};
OS   Plasmodium malariae.
OC   Eukaryota; Sar; Alveolata; Apicomplexa; Aconoidasida; Haemosporida;
OC   Plasmodiidae; Plasmodium; Plasmodium (Plasmodium).
OX   NCBI_TaxID=5858 {ECO:0000313|EMBL:SBS97769.1, ECO:0000313|Proteomes:UP000078597};
RN   [1] {ECO:0000313|Proteomes:UP000078597}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RA   Naeem Raeece;
RL   Submitted (MAY-2016) to the EMBL/GenBank/DDBJ databases.
RN   [2] {ECO:0000313|EMBL:SBS97769.1}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RA   Lavstsen T., Jespersen J.S.;
RL   Submitted (MAY-2016) to the EMBL/GenBank/DDBJ databases.
RN   [3] {ECO:0000313|EMBL:SCN45228.1, ECO:0000313|Proteomes:UP000219813}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RG   Pathogen Informatics;
RL   Submitted (JUN-2016) to the EMBL/GenBank/DDBJ databases.
CC   -!- FUNCTION: S antigens are soluble heat-stable proteins present in the
CC       sera of some infected individuals. {ECO:0000256|ARBA:ARBA00003457}.
CC   -!- SUBCELLULAR LOCATION: Parasitophorous vacuole
CC       {ECO:0000256|ARBA:ARBA00004290}. Vacuole
CC       {ECO:0000256|ARBA:ARBA00004116}.
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DR   EMBL; FLQW01004884; SBS97769.1; -; Genomic_DNA.
DR   EMBL; LT594631; SCN45228.1; -; Genomic_DNA.
DR   OMA; CCHVIDE; -.
DR   Proteomes; UP000078597; Unassembled WGS sequence.
DR   Proteomes; UP000219813; Chromosome 10.
DR   GO; GO:0020003; C:symbiont-containing vacuole; IEA:UniProtKB-SubCell.
DR   GO; GO:0005773; C:vacuole; IEA:UniProtKB-SubCell.
DR   InterPro; IPR010784; Merozoite_SPAM.
DR   InterPro; IPR008825; S-antigen.
DR   Pfam; PF07133; Merozoite_SPAM; 1.
DR   Pfam; PF05756; S-antigen; 1.
PE   4: Predicted;
KW   Reference proteome {ECO:0000313|Proteomes:UP000219813};
KW   Repeat {ECO:0000256|ARBA:ARBA00022737};
KW   Signal {ECO:0000256|ARBA:ARBA00022729, ECO:0000256|SAM:SignalP}.
FT   SIGNAL          1..23
FT                   /evidence="ECO:0000256|SAM:SignalP"
FT   CHAIN           24..405
FT                   /note="S-antigen protein"
FT                   /evidence="ECO:0000256|SAM:SignalP"
FT                   /id="PRO_5015059748"
FT   DOMAIN          1..67
FT                   /note="S-antigen"
FT                   /evidence="ECO:0000259|Pfam:PF05756"
FT   REGION          72..123
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          163..183
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          206..270
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          293..349
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        72..98
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        99..123
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        293..323
FT                   /note="Acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        324..344
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   405 AA;  45973 MW;  5F484961D7092141 CRC64;
     MMRILDITFY LFFLNLYIYI TSSRVINDDN NEQGTFQRKY NLRKGSEYNN KFYGNSVNGL
     ADLQHGDISI RGNDEKLNEG VDASDSSHES EVRRTEGLTR NLVNDNNPGN TALNNSEVSE
     SGTLPIAGTE THKEEEDHDD HQENGTCCHV IDEFIDCNDF DTTSDKESKT SDSHATESTD
     HHKDEECCHV IDEFIDCDDF DTTNDKQSIS GGTQTRHEVA DANQRQEENT SSGDRTTIPQ
     NTGQIRNEGE STRTTVPSPN VTTSDGQNNP YLQEVKEELT ENDEDETVVK ELEEVTEVEE
     QSETEAEKVL EETEEEEEED ELKEVEEKQQ HKAGKSKDES NPSADDTKSY TPYIEEYKYV
     HKTKKAANLF VKSMLRSFSG DLNVADILNG LENDMNNLFY QFVNN
//
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