ID A0A1C1D2Z1_9EURO Unreviewed; 274 AA.
AC A0A1C1D2Z1;
DT 02-NOV-2016, integrated into UniProtKB/TrEMBL.
DT 02-NOV-2016, sequence version 1.
DT 05-FEB-2025, entry version 24.
DE SubName: Full=Protein lifeguard 4 {ECO:0000313|EMBL:OCT55111.1};
GN Name=Tmbim4 {ECO:0000313|EMBL:OCT55111.1};
GN ORFNames=CLCR_03074 {ECO:0000313|EMBL:OCT55111.1};
OS Cladophialophora carrionii.
OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Eurotiomycetes;
OC Chaetothyriomycetidae; Chaetothyriales; Herpotrichiellaceae;
OC Cladophialophora.
OX NCBI_TaxID=86049 {ECO:0000313|EMBL:OCT55111.1, ECO:0000313|Proteomes:UP000094526};
RN [1] {ECO:0000313|Proteomes:UP000094526}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=KSF {ECO:0000313|Proteomes:UP000094526};
RA Teixeira M.M., Souza R.C., Almeida L.G., Vicente V.A., de Hoog S.,
RA Bocca A.L., de Almeida S.R., Vasconcelos A.T., Felipe M.S.;
RL Submitted (JUL-2015) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
CC -!- SIMILARITY: Belongs to the BI1 family. {ECO:0000256|RuleBase:RU004379}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:OCT55111.1}.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; LGRB01000003; OCT55111.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A1C1D2Z1; -.
DR STRING; 86049.A0A1C1D2Z1; -.
DR VEuPathDB; FungiDB:CLCR_03074; -.
DR VEuPathDB; FungiDB:G647_05201; -.
DR eggNOG; KOG2322; Eukaryota.
DR OrthoDB; 7933078at2759; -.
DR Proteomes; UP000094526; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
DR CDD; cd10429; GAAP_like; 1.
DR InterPro; IPR006214; Bax_inhibitor_1-related.
DR PANTHER; PTHR23291; BAX INHIBITOR-RELATED; 1.
DR PANTHER; PTHR23291:SF50; PROTEIN LIFEGUARD 4; 1.
DR Pfam; PF01027; Bax1-I; 1.
PE 3: Inferred from homology;
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|RuleBase:RU004379};
KW Reference proteome {ECO:0000313|Proteomes:UP000094526};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692,
KW ECO:0000256|RuleBase:RU004379};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|RuleBase:RU004379}.
FT TRANSMEM 73..94
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU004379"
FT TRANSMEM 106..124
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU004379"
FT TRANSMEM 160..178
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU004379"
FT TRANSMEM 190..210
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU004379"
FT TRANSMEM 216..236
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU004379"
FT TRANSMEM 248..268
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU004379"
FT REGION 1..42
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 274 AA; 31032 MW; C4F16EB3EC7AF02C CRC64;
MASNTKYQPA PQRDSFDEQH YTQAPPGYQA AGPSDVGYGT PRAEDDNVPD DFKFGGSVSE
ATLDIRMQFI RKVYTILTVQ ILLTAGLSSL SFFSQSYRTW IQSNSWMMWV SLFGAIGFML
LTFWKRKSYP TNMLFLAGFT ALEAYSISVI TSFYESRIVI EALVITLGIF VFLTLFACQT
KYDFTSWMPY LFGALWILII FGFMAAFFPH SSTMETVYGA VAALIFSGYI LVDTQLVMRH
YHVEEEIAAS ISLYLDVLNL FLAILRILNS QNNN
//
