ID A0A1C6UQK0_9ACTN Unreviewed; 585 AA.
AC A0A1C6UQK0;
DT 02-NOV-2016, integrated into UniProtKB/TrEMBL.
DT 02-NOV-2016, sequence version 1.
DT 28-JAN-2026, entry version 35.
DE SubName: Full=Selenocysteine-specific elongation factor {ECO:0000313|EMBL:SCL56345.1};
GN ORFNames=GA0070617_3213 {ECO:0000313|EMBL:SCL56345.1};
OS Micromonospora yangpuensis.
OC Bacteria; Bacillati; Actinomycetota; Actinomycetes; Micromonosporales;
OC Micromonosporaceae; Micromonospora.
OX NCBI_TaxID=683228 {ECO:0000313|EMBL:SCL56345.1, ECO:0000313|Proteomes:UP000198937};
RN [1] {ECO:0000313|EMBL:SCL56345.1, ECO:0000313|Proteomes:UP000198937}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=DSM 45577 {ECO:0000313|EMBL:SCL56345.1,
RC ECO:0000313|Proteomes:UP000198937};
RA Kjaerup R.B., Dalgaard T.S., Juul-Madsen H.R.;
RL Submitted (JUN-2016) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000256|ARBA:ARBA00004496}.
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DR EMBL; FMIA01000002; SCL56345.1; -; Genomic_DNA.
DR RefSeq; WP_091438513.1; NZ_BMMJ01000005.1.
DR AlphaFoldDB; A0A1C6UQK0; -.
DR STRING; 683228.GA0070617_3213; -.
DR OrthoDB; 9803139at2; -.
DR Proteomes; UP000198937; Unassembled WGS sequence.
DR GO; GO:0005829; C:cytosol; IEA:TreeGrafter.
DR GO; GO:0005525; F:GTP binding; IEA:UniProtKB-KW.
DR GO; GO:0003924; F:GTPase activity; IEA:InterPro.
DR GO; GO:0003723; F:RNA binding; IEA:InterPro.
DR GO; GO:0003746; F:translation elongation factor activity; IEA:UniProtKB-KW.
DR GO; GO:0001514; P:selenocysteine incorporation; IEA:InterPro.
DR CDD; cd04171; SelB; 1.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 1.
DR Gene3D; 2.40.30.10; Translation factors; 1.
DR Gene3D; 1.10.10.10; Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain; 1.
DR InterPro; IPR057335; Beta-barrel_SelB.
DR InterPro; IPR050055; EF-Tu_GTPase.
DR InterPro; IPR027417; P-loop_NTPase.
DR InterPro; IPR015191; SelB_WHD4.
DR InterPro; IPR000795; T_Tr_GTP-bd_dom.
DR InterPro; IPR009000; Transl_B-barrel_sf.
DR InterPro; IPR004535; Transl_elong_SelB.
DR InterPro; IPR036388; WH-like_DNA-bd_sf.
DR InterPro; IPR036390; WH_DNA-bd_sf.
DR NCBIfam; TIGR00475; selB; 1.
DR PANTHER; PTHR43721:SF22; ELONGATION FACTOR TU, MITOCHONDRIAL; 1.
DR PANTHER; PTHR43721; ELONGATION FACTOR TU-RELATED; 1.
DR Pfam; PF25461; Beta-barrel_SelB; 1.
DR Pfam; PF00009; GTP_EFTU; 1.
DR Pfam; PF09107; WHD_3rd_SelB; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR SUPFAM; SSF50447; Translation proteins; 1.
DR SUPFAM; SSF46785; Winged helix' DNA-binding domain; 1.
DR PROSITE; PS51722; G_TR_2; 1.
PE 4: Predicted;
KW Cytoplasm {ECO:0000256|ARBA:ARBA00022490};
KW Elongation factor {ECO:0000313|EMBL:SCL56345.1};
KW GTP-binding {ECO:0000256|ARBA:ARBA00023134};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00023134};
KW Protein biosynthesis {ECO:0000256|ARBA:ARBA00022917};
KW Reference proteome {ECO:0000313|Proteomes:UP000198937}.
FT DOMAIN 1..170
FT /note="Tr-type G"
FT /evidence="ECO:0000259|PROSITE:PS51722"
SQ SEQUENCE 585 AA; 61620 MW; 14D659F3FB2DD128 CRC64;
MWVVATAGHV DHGKSTLVRA LTGMEPDRWA EERRRGMTID LGFAWTTLPG GATVAFVDVP
GHERFVPNML AGVGPVPAVL VVVAADEGWM PQSAEHLAAL DALGVSAGLL VVTRADLADP
RMALTRAREE LAGTSLAGVE AVAVSAVTGA GLPRLREALG RLVAGMAPPV VDAPVRLWVD
RSFTVRGAGT VVTGTLAAGR LRVDDVLEVT GLGAPVRVRG LQSLGVARSE VSAVARVAVN
LRGVPRERVG RGDALLSPGR FALSAVWDVR LSGVPVAQLP ATAMVHVGSA QVAVRLRPLG
VDTVRLRLDR PLPVLVGDRA LLRDPGRRCV VAGVRVLDTD PPVLRRRGAA AARAVVLADV
DGVADLVGEV RRRRLVRAGD LRRMGVSTAG AVPVAGDWLA DVDYWARCRV ALAVEVERYG
RERPLEPGPP VEVLRRRLGL PERVLVVALV RAPLRVVDGR VVAEGAGGLP VPVARAVDRL
RVEFAGCRFR APEADRLAGW GLGPREVAAA VRAGVLLRLP GNVVLLPGVP QEAARVLAGL
PQPFTVGAAR RALDTTRRVA VPLLELLDAT GVTRRHADDS RSVVG
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