ID A0A1D3PBG8_PLAMA Unreviewed; 698 AA.
AC A0A1D3PBG8;
DT 30-NOV-2016, integrated into UniProtKB/TrEMBL.
DT 30-NOV-2016, sequence version 1.
DT 02-APR-2025, entry version 33.
DE RecName: Full=RBR-type E3 ubiquitin transferase {ECO:0000256|ARBA:ARBA00012251};
DE EC=2.3.2.31 {ECO:0000256|ARBA:ARBA00012251};
GN Name=PmUG01_08052400 {ECO:0000313|EMBL:SCN12394.1};
GN ORFNames=PMUG01_08052400 {ECO:0000313|EMBL:SCN12394.1};
OS Plasmodium malariae.
OC Eukaryota; Sar; Alveolata; Apicomplexa; Aconoidasida; Haemosporida;
OC Plasmodiidae; Plasmodium; Plasmodium (Plasmodium).
OX NCBI_TaxID=5858 {ECO:0000313|EMBL:SCN12394.1, ECO:0000313|Proteomes:UP000219813};
RN [1] {ECO:0000313|EMBL:SCN12394.1, ECO:0000313|Proteomes:UP000219813}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RG Pathogen Informatics;
RL Submitted (JUN-2016) to the EMBL/GenBank/DDBJ databases.
CC -!- CATALYTIC ACTIVITY:
CC Reaction=[E2 ubiquitin-conjugating enzyme]-S-ubiquitinyl-L-cysteine +
CC [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-
CC cysteine + [acceptor protein]-N(6)-ubiquitinyl-L-lysine.;
CC EC=2.3.2.31; Evidence={ECO:0000256|ARBA:ARBA00001798};
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DR EMBL; LT594629; SCN12394.1; -; Genomic_DNA.
DR RefSeq; XP_028861365.1; XM_029004703.1.
DR AlphaFoldDB; A0A1D3PBG8; -.
DR GeneID; 39868506; -.
DR VEuPathDB; PlasmoDB:PmUG01_08052400; -.
DR OMA; YIIESIM; -.
DR OrthoDB; 10009520at2759; -.
DR Proteomes; UP000219813; Chromosome 8.
DR GO; GO:0004842; F:ubiquitin-protein transferase activity; IEA:InterPro.
DR GO; GO:0008270; F:zinc ion binding; IEA:UniProtKB-KW.
DR GO; GO:0016567; P:protein ubiquitination; IEA:InterPro.
DR Gene3D; 1.20.120.1750; -; 2.
DR InterPro; IPR031127; E3_UB_ligase_RBR.
DR InterPro; IPR002867; IBR_dom.
DR InterPro; IPR044066; TRIAD_supradom.
DR PANTHER; PTHR11685; RBR FAMILY RING FINGER AND IBR DOMAIN-CONTAINING; 1.
DR Pfam; PF01485; IBR; 1.
DR Pfam; PF22191; IBR_1; 1.
DR SMART; SM00647; IBR; 2.
DR SUPFAM; SSF57850; RING/U-box; 3.
DR PROSITE; PS51873; TRIAD; 1.
PE 4: Predicted;
KW Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW Reference proteome {ECO:0000313|Proteomes:UP000219813};
KW Repeat {ECO:0000256|ARBA:ARBA00022737};
KW Transferase {ECO:0000256|ARBA:ARBA00022679};
KW Ubl conjugation pathway {ECO:0000256|ARBA:ARBA00022786};
KW Zinc {ECO:0000256|ARBA:ARBA00022833};
KW Zinc-finger {ECO:0000256|ARBA:ARBA00022771}.
FT DOMAIN 259..468
FT /note="RING-type"
FT /evidence="ECO:0000259|PROSITE:PS51873"
FT REGION 37..106
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 477..549
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 37..99
FT /note="Low complexity"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 698 AA; 83175 MW; 7D89F37077E40C62 CRC64;
MNIPKENTST KLEVTIEFGK DKKLKVVKKL ISNNNVRNVD NNISNDNRNS NSSSNSNDNS
NSNRNSNRNS NRNSNRNSNR NSNRNSNSSS NSSSNSSSNY KIKEEPTQSL FSQENYEEGM
KIYLEYFKKN FTKYQENSIY NVHNTTDIKQ KMKETISDLM NLINVEYDYA YHFLKAYNFN
SDNLIEAWFK NSKDVLMKSD LCHIMEKEIM NEKGGYAIPT GNNASDTDEG GHYVNASNQV
DHRDNTLLVP QLGDTGKRQK YTCPVLLNEY DMKDTYALNC GHRYSKECWL RYLETSLSTD
FEENVIIKKC IHLDCKEIAK MKDWKCICTE KLYEKYEQIL VQIFINKSYN LKKCPNVNCE
YIIESIMLKN NNVVCKCGFN FCFLCSHEFH RPVTCTLIKQ WKELQIKDDH NIKWISIHTK
KCPNCNKSIE KASGCMNVKC ICSFSFCWLC LESWNNHKGG FYKCNKYIEN NKTNENEMNK
EQKEQQEQKE QEQKEQEQKE QEQKEQEQKE QEQKEQEQKE QEQKEQEQQE PQEQKEQKEQ
KQKEQKEQVK RNYHSILNKY NHFKTRFDAH QHGEEFSIST QLLFLHNFCK SNNIQLHKMK
TFEDSIIQTI KCRQILKWSY AFAYFSNWKD ENQKYFFEYH QGELEKNLDM LQRKTENIDI
YQFINNRYDK NVREIEELIK VVHVFFKNIC DFIESNFS
//
