ID A0A1E4S4Q8_CYBJN Unreviewed; 528 AA.
AC A0A1E4S4Q8;
DT 18-JAN-2017, integrated into UniProtKB/TrEMBL.
DT 18-JAN-2017, sequence version 1.
DT 18-JUN-2025, entry version 31.
DE RecName: Full=U three protein 7 {ECO:0000256|ARBA:ARBA00076453};
GN ORFNames=CYBJADRAFT_167102 {ECO:0000313|EMBL:ODV74433.1};
OS Cyberlindnera jadinii (strain ATCC 18201 / CBS 1600 / BCRC 20928 / JCM 3617
OS / NBRC 0987 / NRRL Y-1542) (Torula yeast) (Candida utilis).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes;
OC Phaffomycetales; Phaffomycetaceae; Cyberlindnera.
OX NCBI_TaxID=983966 {ECO:0000313|EMBL:ODV74433.1, ECO:0000313|Proteomes:UP000094389};
RN [1] {ECO:0000313|EMBL:ODV74433.1, ECO:0000313|Proteomes:UP000094389}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 18201 / CBS 1600 / BCRC 20928 / JCM 3617 / NBRC 0987 /
RC NRRL Y-1542 {ECO:0000313|Proteomes:UP000094389};
RX PubMed=27535936; DOI=10.1073/pnas.1603941113;
RA Riley R., Haridas S., Wolfe K.H., Lopes M.R., Hittinger C.T., Goeker M.,
RA Salamov A.A., Wisecaver J.H., Long T.M., Calvey C.H., Aerts A.L.,
RA Barry K.W., Choi C., Clum A., Coughlan A.Y., Deshpande S., Douglass A.P.,
RA Hanson S.J., Klenk H.-P., LaButti K.M., Lapidus A., Lindquist E.A.,
RA Lipzen A.M., Meier-Kolthoff J.P., Ohm R.A., Otillar R.P., Pangilinan J.L.,
RA Peng Y., Rokas A., Rosa C.A., Scheuner C., Sibirny A.A., Slot J.C.,
RA Stielow J.B., Sun H., Kurtzman C.P., Blackwell M., Grigoriev I.V.,
RA Jeffries T.W.;
RT "Comparative genomics of biotechnologically important yeasts.";
RL Proc. Natl. Acad. Sci. U.S.A. 113:9882-9887(2016).
CC -!- FUNCTION: Involved in nucleolar processing of pre-18S ribosomal RNA.
CC {ECO:0000256|ARBA:ARBA00004099}.
CC -!- SUBCELLULAR LOCATION: Nucleus, nucleolus
CC {ECO:0000256|ARBA:ARBA00004604}.
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DR EMBL; KV453928; ODV74433.1; -; Genomic_DNA.
DR RefSeq; XP_020071472.1; XM_020214768.1.
DR AlphaFoldDB; A0A1E4S4Q8; -.
DR STRING; 983966.A0A1E4S4Q8; -.
DR GeneID; 30989164; -.
DR OMA; EFLPYHW; -.
DR OrthoDB; 10251154at2759; -.
DR Proteomes; UP000094389; Unassembled WGS sequence.
DR GO; GO:0030686; C:90S preribosome; IEA:TreeGrafter.
DR GO; GO:0005730; C:nucleolus; IEA:UniProtKB-SubCell.
DR GO; GO:0032040; C:small-subunit processome; IEA:TreeGrafter.
DR GO; GO:0000462; P:maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA); IEA:TreeGrafter.
DR FunFam; 2.130.10.10:FF:000378; U3 small nucleolar RNA-associated protein 7; 1.
DR Gene3D; 2.130.10.10; YVTN repeat-like/Quinoprotein amine dehydrogenase; 1.
DR InterPro; IPR012952; BING4_C_dom.
DR InterPro; IPR015943; WD40/YVTN_repeat-like_dom_sf.
DR InterPro; IPR036322; WD40_repeat_dom_sf.
DR InterPro; IPR001680; WD40_rpt.
DR InterPro; IPR040315; WDR46/Utp7.
DR PANTHER; PTHR14085:SF3; WD REPEAT-CONTAINING PROTEIN 46; 1.
DR PANTHER; PTHR14085; WD-REPEAT PROTEIN BING4; 1.
DR Pfam; PF08149; BING4CT; 1.
DR Pfam; PF00400; WD40; 1.
DR SMART; SM01033; BING4CT; 1.
DR SMART; SM00320; WD40; 5.
DR SUPFAM; SSF50978; WD40 repeat-like; 1.
DR PROSITE; PS50082; WD_REPEATS_2; 1.
PE 4: Predicted;
KW Nucleus {ECO:0000256|ARBA:ARBA00023242};
KW Reference proteome {ECO:0000313|Proteomes:UP000094389};
KW Repeat {ECO:0000256|ARBA:ARBA00022737};
KW rRNA processing {ECO:0000256|ARBA:ARBA00022552};
KW WD repeat {ECO:0000256|ARBA:ARBA00022574, ECO:0000256|PROSITE-
KW ProRule:PRU00221}.
FT REPEAT 265..306
FT /note="WD"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00221"
FT DOMAIN 346..425
FT /note="BING4 C-terminal"
FT /evidence="ECO:0000259|SMART:SM01033"
FT REGION 1..46
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 438..486
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 10..21
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 32..46
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 438..464
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 472..481
FT /note="Basic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 528 AA; 59706 MW; F4212BEC128C1307 CRC64;
MGKFTGKNGS VDHENQSKFE RGPNGGKKSG RRPKDFRTRQ RMNKIDDQYK EAVRSAAATE
MLLQEDAGYL EAEGMEKTFK FKQDEIKQAV DESTANKAFQ LDLKEFGPYT LDYSRNGTHL
LIGGEKGHVA SMDWRKGELR AELHLGETVN AVKYLHNEQF FAVAQKKYTF IYDHEGTEVH
RLKQHVEIKH LEFLPYHYLL ATSGNSGFLK YQDTSTGVLV NEIRTKLGPT QSMTQNPWNA
VIHLGSATGV VSLWSPAANE PLVKIQACRG PVKAIGVDRS GHYMAVAGAD KSLKIWDVRQ
FKEVYSYYTP TPASSISIAD TGVLSVSWGP HVTVWKDAFR TKQDSPYMNH MIPGSRINTI
RHVPFEDILG VGHTSGVSSL IIPGSGEANF DSMEVNPFET AKQRQETEVR SLLNKLPADS
IALDPNFIGT VDKRSNAQRL KPHELEELTK KKQLEEESKL EPRPTVRGKN SALRRHMRKR
QQNVIDERKL RLEANLKREK ELRAQMIRKQ KGLPEEKELL GPALARFK
//
