ID A0A1E5R2B3_9ASCO Unreviewed; 904 AA.
AC A0A1E5R2B3;
DT 18-JAN-2017, integrated into UniProtKB/TrEMBL.
DT 18-JAN-2017, sequence version 1.
DT 18-JUN-2025, entry version 30.
DE SubName: Full=DDK kinase regulatory subunit DBF4 {ECO:0000313|EMBL:OEJ80703.1};
GN ORFNames=AWRI3579_g4259 {ECO:0000313|EMBL:OEJ80703.1};
OS Hanseniaspora osmophila.
OC Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes;
OC Saccharomycodales; Saccharomycodaceae; Hanseniaspora.
OX NCBI_TaxID=56408 {ECO:0000313|EMBL:OEJ80703.1, ECO:0000313|Proteomes:UP000095728};
RN [1] {ECO:0000313|Proteomes:UP000095728}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=AWRI3579 {ECO:0000313|Proteomes:UP000095728};
RX PubMed=27856586; DOI=10.1128/genomea.01287-16;
RA Sternes P.R., Lee D., Kutyna D.R., Borneman A.R.;
RT "Genome sequences of three species of Hanseniaspora isolated from
RT spontaneous wine fermentations.";
RL Genome Announc. 4:E01287-E01287(2016).
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:OEJ80703.1}.
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DR EMBL; LPNM01000011; OEJ80703.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A1E5R2B3; -.
DR FunCoup; A0A1E5R2B3; 190.
DR STRING; 56408.A0A1E5R2B3; -.
DR InParanoid; A0A1E5R2B3; -.
DR OrthoDB; 3973118at2759; -.
DR Proteomes; UP000095728; Unassembled WGS sequence.
DR GO; GO:0031431; C:Dbf4-dependent protein kinase complex; IEA:TreeGrafter.
DR GO; GO:0016301; F:kinase activity; IEA:UniProtKB-KW.
DR GO; GO:0003676; F:nucleic acid binding; IEA:InterPro.
DR GO; GO:0043539; F:protein serine/threonine kinase activator activity; IEA:TreeGrafter.
DR GO; GO:0008270; F:zinc ion binding; IEA:UniProtKB-KW.
DR GO; GO:0010571; P:positive regulation of nuclear cell cycle DNA replication; IEA:TreeGrafter.
DR GO; GO:1901987; P:regulation of cell cycle phase transition; IEA:TreeGrafter.
DR FunFam; 6.10.250.3410:FF:000001; Protein DBF4 homolog A; 1.
DR Gene3D; 3.40.50.10190; BRCT domain; 1.
DR Gene3D; 6.10.250.3410; DBF zinc finger; 1.
DR InterPro; IPR036420; BRCT_dom_sf.
DR InterPro; IPR055116; DBF4_BRCT.
DR InterPro; IPR013939; Regulatory_Dfp1/Him1.
DR InterPro; IPR051590; Replication_Regulatory_Kinase.
DR InterPro; IPR006572; Znf_DBF.
DR InterPro; IPR038545; Znf_DBF_sf.
DR PANTHER; PTHR15375; ACTIVATOR OF S-PHASE KINASE-RELATED; 1.
DR PANTHER; PTHR15375:SF26; PROTEIN CHIFFON; 1.
DR Pfam; PF22437; DBF4_BRCT; 1.
DR Pfam; PF08630; Dfp1_Him1_M; 1.
DR Pfam; PF07535; zf-DBF; 1.
DR SMART; SM00586; ZnF_DBF; 1.
DR PROSITE; PS51265; ZF_DBF4; 1.
PE 4: Predicted;
KW Kinase {ECO:0000313|EMBL:OEJ80703.1};
KW Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW Reference proteome {ECO:0000313|Proteomes:UP000095728};
KW Transferase {ECO:0000313|EMBL:OEJ80703.1};
KW Zinc {ECO:0000256|ARBA:ARBA00022833};
KW Zinc-finger {ECO:0000256|ARBA:ARBA00022771, ECO:0000256|PROSITE-
KW ProRule:PRU00600}.
FT DOMAIN 853..902
FT /note="DBF4-type"
FT /evidence="ECO:0000259|PROSITE:PS51265"
FT REGION 273..297
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 527..553
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 654..698
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 662..681
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 904 AA; 99972 MW; E7364892F4CF7555 CRC64;
MNNFASTGST RRIPLGETNA NQLSLSQTGS LSQKANLAAS TVTKKHNYQF FKDNWEHTKA
KPVADPQSNS RDSEHGLANM QEDTEVDVTD AAAENGDGPL HDAPEALQQN QNFQKGDEHD
ASLLACGVVG QDKNSLVQIT PKDSTSYRKR LSESLDRQTH NNACALEEGA RRKLTTAEFL
RKNSGQIAVD AIDAEYQEEK KTSVLDDPMY LSKNKHIATP ITKSRRSIGG ASLVNPMYTK
ILPIQSTVQN IGGKPTLTTV SDKEQTNVEM GKVTNKNTTS GNTTTSRSVG ATGTTGVSGT
AKNSAAMNLK VWQTNWKNIM KKETVIYFDI QEGVATGGKT GAQEMKTLRE KDSTKALIAL
ETLRLGYYSL GAAVSKFFDR EVTIVITDRS NDASFIKSLS ESDVLKKASK NDMKIWTLEK
AERFLTHLDV DISKMKKKAL NSAALGNASK NGLVSKFGNA IVAAQTTTET GTLRRYLQNE
KLYGPMDRDP LAKRDDMHYF SKDRPHIYIY DLNQQFSPLV IMEWKTNKSN SEPGNDLSKD
GAGTKNDADL PYPTLKNSTF GRCPFIADNE DETSDKRIFK RLKKDMNQQD QAEFLLRLYS
TTAVPNPMND IYLLNHDKYN DSGKNFYKKF GYHFDELPFA KNNKNSEKSI GKVKIHEPKT
PANKNAQQDN QKSNSPKNNS DMGEDGESPK LPQKVVWKRP PLKNKVNIEN LLRMETTGLD
DSNGFNGVGK NDTATGASFA GKKRPMLSEI KASGVLNNDP INNSSTQPFQ ANNGLAATKS
TVVGKQMNAL NSKFVVMDPV PANCNVPKTP STHVSVPLKP KERIAGSKIS LGNKSPVTRK
PNTIAINAAI RDKRMGGGYC ENCRVKYESL RLHIKTEKHL EFAQKDQNFY AIDSLIENLH
SSMY
//
