ID A0A1H0AY51_9BRAD Unreviewed; 210 AA.
AC A0A1H0AY51;
DT 18-JAN-2017, integrated into UniProtKB/TrEMBL.
DT 18-JAN-2017, sequence version 1.
DT 02-APR-2025, entry version 22.
DE RecName: Full=acyl-homoserine-lactone synthase {ECO:0000256|ARBA:ARBA00012340};
DE EC=2.3.1.184 {ECO:0000256|ARBA:ARBA00012340};
GN ORFNames=SAMN05444050_1432 {ECO:0000313|EMBL:SDN38384.1};
OS Afipia sp. GAS231.
OC Bacteria; Pseudomonadati; Pseudomonadota; Alphaproteobacteria;
OC Hyphomicrobiales; Nitrobacteraceae; Afipia.
OX NCBI_TaxID=1882747 {ECO:0000313|EMBL:SDN38384.1, ECO:0000313|Proteomes:UP000198617};
RN [1] {ECO:0000313|EMBL:SDN38384.1, ECO:0000313|Proteomes:UP000198617}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=GAS231 {ECO:0000313|EMBL:SDN38384.1,
RC ECO:0000313|Proteomes:UP000198617};
RA de Groot N.N.;
RL Submitted (OCT-2016) to the EMBL/GenBank/DDBJ databases.
CC -!- CATALYTIC ACTIVITY:
CC Reaction=a fatty acyl-[ACP] + S-adenosyl-L-methionine = an N-acyl-L-
CC homoserine lactone + S-methyl-5'-thioadenosine + holo-[ACP] + H(+);
CC Xref=Rhea:RHEA:10096, Rhea:RHEA-COMP:9685, Rhea:RHEA-COMP:14125,
CC ChEBI:CHEBI:15378, ChEBI:CHEBI:17509, ChEBI:CHEBI:55474,
CC ChEBI:CHEBI:59789, ChEBI:CHEBI:64479, ChEBI:CHEBI:138651;
CC EC=2.3.1.184; Evidence={ECO:0000256|ARBA:ARBA00048576};
CC -!- SIMILARITY: Belongs to the autoinducer synthase family.
CC {ECO:0000256|PROSITE-ProRule:PRU00533}.
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DR EMBL; LT629703; SDN38384.1; -; Genomic_DNA.
DR RefSeq; WP_092517732.1; NZ_LT629703.1.
DR AlphaFoldDB; A0A1H0AY51; -.
DR STRING; 1882747.SAMN05444050_1432; -.
DR OrthoDB; 6169313at2; -.
DR Proteomes; UP000198617; Chromosome i.
DR GO; GO:0061579; F:N-acyl homoserine lactone synthase activity; IEA:UniProtKB-EC.
DR GO; GO:0009372; P:quorum sensing; IEA:UniProtKB-UniRule.
DR GO; GO:0007165; P:signal transduction; IEA:TreeGrafter.
DR Gene3D; 3.40.630.30; -; 1.
DR InterPro; IPR016181; Acyl_CoA_acyltransferase.
DR InterPro; IPR018311; Autoind_synth_CS.
DR InterPro; IPR001690; Autoind_synthase.
DR PANTHER; PTHR39322; ACYL-HOMOSERINE-LACTONE SYNTHASE; 1.
DR PANTHER; PTHR39322:SF1; ISOVALERYL-HOMOSERINE LACTONE SYNTHASE; 1.
DR Pfam; PF00765; Autoind_synth; 1.
DR PRINTS; PR01549; AUTOINDCRSYN.
DR SUPFAM; SSF55729; Acyl-CoA N-acyltransferases (Nat); 1.
DR PROSITE; PS00949; AUTOINDUCER_SYNTH_1; 1.
DR PROSITE; PS51187; AUTOINDUCER_SYNTH_2; 1.
PE 3: Inferred from homology;
KW Autoinducer synthesis {ECO:0000256|ARBA:ARBA00022929, ECO:0000256|PROSITE-
KW ProRule:PRU00533};
KW Quorum sensing {ECO:0000256|ARBA:ARBA00022654, ECO:0000256|PROSITE-
KW ProRule:PRU00533}; Reference proteome {ECO:0000313|Proteomes:UP000198617};
KW S-adenosyl-L-methionine {ECO:0000256|ARBA:ARBA00022691}.
SQ SEQUENCE 210 AA; 23109 MW; 07E0F320EE7D0E70 CRC64;
MIQLITERCY GEFAEALISM HRLRYRVFKE RLDWDVHTSG DMEVDSFDAL HPAYLLQLAT
DGRPQGCVRL LPSVGPTMLS ETFPVLLAGQ RAPSTCSIWE SSRFALDLAA DAPKGKHAIA
CATYELFAGM IEFGLSRRLS DIVTVTDARM ERILRRAGWP LRRLGNPRSL GNTMAVAGYL
EISAEVLAAI RSAGGFTGPV LWEPVVLAVA
//
