ID   A0A1H2F8I6_9GAMM        Unreviewed;       626 AA.
AC   A0A1H2F8I6;
DT   18-JAN-2017, integrated into UniProtKB/TrEMBL.
DT   18-JAN-2017, sequence version 1.
DT   28-JAN-2026, entry version 33.
DE   SubName: Full=Selenocysteine-specific elongation factor {ECO:0000313|EMBL:SDU03642.1};
GN   ORFNames=SAMN05216210_1370 {ECO:0000313|EMBL:SDU03642.1};
OS   Halopseudomonas salegens.
OC   Bacteria; Pseudomonadati; Pseudomonadota; Gammaproteobacteria;
OC   Pseudomonadales; Pseudomonadaceae; Halopseudomonas.
OX   NCBI_TaxID=1434072 {ECO:0000313|EMBL:SDU03642.1, ECO:0000313|Proteomes:UP000243924};
RN   [1] {ECO:0000313|Proteomes:UP000243924}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=CECT 8338 {ECO:0000313|Proteomes:UP000243924};
RA   Varghese N., Submissions S.;
RL   Submitted (OCT-2016) to the EMBL/GenBank/DDBJ databases.
CC   -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000256|ARBA:ARBA00004496}.
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DR   EMBL; LT629787; SDU03642.1; -; Genomic_DNA.
DR   RefSeq; WP_092385407.1; NZ_LT629787.1.
DR   AlphaFoldDB; A0A1H2F8I6; -.
DR   STRING; 1434072.SAMN05216210_1370; -.
DR   OrthoDB; 9803139at2; -.
DR   Proteomes; UP000243924; Chromosome I.
DR   GO; GO:0005829; C:cytosol; IEA:TreeGrafter.
DR   GO; GO:0005525; F:GTP binding; IEA:UniProtKB-KW.
DR   GO; GO:0003924; F:GTPase activity; IEA:InterPro.
DR   GO; GO:0035368; F:selenocysteine insertion sequence binding; IEA:TreeGrafter.
DR   GO; GO:0003746; F:translation elongation factor activity; IEA:UniProtKB-KW.
DR   GO; GO:0000049; F:tRNA binding; IEA:TreeGrafter.
DR   GO; GO:0001514; P:selenocysteine incorporation; IEA:InterPro.
DR   GO; GO:0016259; P:selenocysteine metabolic process; IEA:TreeGrafter.
DR   CDD; cd04171; SelB; 1.
DR   Gene3D; 1.10.10.2770; -; 1.
DR   Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 1.
DR   Gene3D; 2.40.30.10; Translation factors; 1.
DR   Gene3D; 1.10.10.10; Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain; 1.
DR   InterPro; IPR057335; Beta-barrel_SelB.
DR   InterPro; IPR050543; eIF2G.
DR   InterPro; IPR027417; P-loop_NTPase.
DR   InterPro; IPR015191; SelB_WHD4.
DR   InterPro; IPR000795; T_Tr_GTP-bd_dom.
DR   InterPro; IPR009000; Transl_B-barrel_sf.
DR   InterPro; IPR004535; Transl_elong_SelB.
DR   InterPro; IPR036388; WH-like_DNA-bd_sf.
DR   InterPro; IPR036390; WH_DNA-bd_sf.
DR   NCBIfam; TIGR00475; selB; 1.
DR   PANTHER; PTHR42854; EUKARYOTIC TRANSLATION INITIATION FACTOR 2 SUBUNIT 3 FAMILY MEMBER; 1.
DR   PANTHER; PTHR42854:SF3; EUKARYOTIC TRANSLATION INITIATION FACTOR 2 SUBUNIT 3-RELATED; 1.
DR   Pfam; PF25461; Beta-barrel_SelB; 1.
DR   Pfam; PF00009; GTP_EFTU; 1.
DR   Pfam; PF09107; WHD_3rd_SelB; 1.
DR   PRINTS; PR00315; ELONGATNFCT.
DR   SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR   SUPFAM; SSF50447; Translation proteins; 1.
DR   SUPFAM; SSF46785; Winged helix' DNA-binding domain; 1.
DR   PROSITE; PS51722; G_TR_2; 1.
PE   4: Predicted;
KW   Cytoplasm {ECO:0000256|ARBA:ARBA00022490};
KW   Elongation factor {ECO:0000313|EMBL:SDU03642.1};
KW   GTP-binding {ECO:0000256|ARBA:ARBA00023134};
KW   Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741};
KW   Protein biosynthesis {ECO:0000256|ARBA:ARBA00022917};
KW   Reference proteome {ECO:0000313|Proteomes:UP000243924}.
FT   DOMAIN          1..170
FT                   /note="Tr-type G"
FT                   /evidence="ECO:0000259|PROSITE:PS51722"
SQ   SEQUENCE   626 AA;  67925 MW;  CD3B26C141C9F478 CRC64;
     MIIATAGHVD HGKTTLIQAL TGKNTDRLAD EQRRGLTIDL GFAWRHDPHA GAIAFVDVPG
     HSRFIRTMLA GLAGADAALL VIAADEGPMP QTREHLALLD LLGIAQGLVV LTAIDRASSK
     QRAATRQAAI ELLQGTTLAN SPLLEVSAIT GQGIDDLQVA ITELAQSIPA RHCTGNPRFL
     VDRRFSVTGS GCVVTGTLLN GELHTDSHLC LTPVAGSVRI RGMQRDGQAI TALKAGQRAA
     LNLAGDLDAD HPQRGDWLLA PEMHQLTDRL DISLRLLPDA KLHRGTLQVL AGAAASSGRV
     VWLDESAGLA QVLLDHGLHA IQGDPVIVRE PAANQTLGGG RVIDPLGRQR GRSKPEALSR
     LRALQPVDSP DIALGVELAQ QKEVDIAAFA RRWNLTPNEL AALLAAEPLV HLGGQALHPE
     RVAQAEHSIV QRLQQAHTEQ PEQRGLPQHA LLRAAAIGLS PPSSGLLLKR MVSHQQLQQQ
     GGIYALPNHQ PQLPTSDLLL WEKVAAELNK SKLRPPIVGE MAESLGHSRE EMLAFMQRMQ
     QWGYVLGVAH NRFYLPEQLD ELAAVAVELC NQSPDGGFVA AEYRDQSGIG RNLTIQVLEY
     LDRVGVTWYR KQRRFLQPAW QREQKH
//