ID A0A1H3FUU7_9FLAO Unreviewed; 576 AA.
AC A0A1H3FUU7;
DT 22-NOV-2017, integrated into UniProtKB/TrEMBL.
DT 22-NOV-2017, sequence version 1.
DT 08-OCT-2025, entry version 25.
DE RecName: Full=histidine kinase {ECO:0000256|ARBA:ARBA00012438};
DE EC=2.7.13.3 {ECO:0000256|ARBA:ARBA00012438};
GN ORFNames=SAMN05444411_11265 {ECO:0000313|EMBL:SDX94832.1};
OS Lutibacter oricola.
OC Bacteria; Pseudomonadati; Bacteroidota; Flavobacteriia; Flavobacteriales;
OC Flavobacteriaceae; Lutibacter.
OX NCBI_TaxID=762486 {ECO:0000313|EMBL:SDX94832.1, ECO:0000313|Proteomes:UP000199595};
RN [1] {ECO:0000313|EMBL:SDX94832.1, ECO:0000313|Proteomes:UP000199595}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=DSM 24956 {ECO:0000313|EMBL:SDX94832.1,
RC ECO:0000313|Proteomes:UP000199595};
RA de Groot N.N.;
RL Submitted (OCT-2016) to the EMBL/GenBank/DDBJ databases.
CC -!- CATALYTIC ACTIVITY:
CC Reaction=ATP + protein L-histidine = ADP + protein N-phospho-L-
CC histidine.; EC=2.7.13.3; Evidence={ECO:0000256|ARBA:ARBA00000085};
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004370}.
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DR EMBL; FNNJ01000012; SDX94832.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A1H3FUU7; -.
DR STRING; 762486.SAMN05444411_11265; -.
DR OrthoDB; 9806995at2; -.
DR Proteomes; UP000199595; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0000155; F:phosphorelay sensor kinase activity; IEA:InterPro.
DR CDD; cd06225; HAMP; 1.
DR CDD; cd00082; HisKA; 1.
DR Gene3D; 1.10.287.130; -; 1.
DR Gene3D; 6.10.340.10; -; 1.
DR Gene3D; 3.30.565.10; Histidine kinase-like ATPase, C-terminal domain; 1.
DR InterPro; IPR033417; CHASE8.
DR InterPro; IPR003660; HAMP_dom.
DR InterPro; IPR036890; HATPase_C_sf.
DR InterPro; IPR003594; HATPase_dom.
DR InterPro; IPR005467; His_kinase_dom.
DR InterPro; IPR003661; HisK_dim/P_dom.
DR InterPro; IPR036097; HisK_dim/P_sf.
DR InterPro; IPR004358; Sig_transdc_His_kin-like_C.
DR PANTHER; PTHR43065:SF48; HISTIDINE KINASE; 1.
DR PANTHER; PTHR43065; SENSOR HISTIDINE KINASE; 1.
DR Pfam; PF17152; CHASE8; 1.
DR Pfam; PF00672; HAMP; 1.
DR Pfam; PF02518; HATPase_c; 1.
DR PRINTS; PR00344; BCTRLSENSOR.
DR SMART; SM00304; HAMP; 1.
DR SMART; SM00387; HATPase_c; 1.
DR SUPFAM; SSF55874; ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase; 1.
DR SUPFAM; SSF158472; HAMP domain-like; 1.
DR SUPFAM; SSF47384; Homodimeric domain of signal transducing histidine kinase; 1.
DR PROSITE; PS50885; HAMP; 1.
DR PROSITE; PS50109; HIS_KIN; 1.
PE 4: Predicted;
KW Coiled coil {ECO:0000256|SAM:Coils};
KW Kinase {ECO:0000256|ARBA:ARBA00022777}; Membrane {ECO:0000256|SAM:Phobius};
KW Phosphoprotein {ECO:0000256|ARBA:ARBA00022553};
KW Reference proteome {ECO:0000313|Proteomes:UP000199595};
KW Transferase {ECO:0000256|ARBA:ARBA00022679};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT TRANSMEM 12..33
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 158..176
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 181..234
FT /note="HAMP"
FT /evidence="ECO:0000259|PROSITE:PS50885"
FT DOMAIN 347..574
FT /note="Histidine kinase"
FT /evidence="ECO:0000259|PROSITE:PS50109"
FT COILED 219..263
FT /evidence="ECO:0000256|SAM:Coils"
SQ SEQUENCE 576 AA; 65656 MW; FCE4FB8FBB58192D CRC64;
MLFKNQSIKL KLILIIQFVS LLSLLIGFTY VIYSNISYYK DDMRNNAIIN ATLIGDYCTV
PLVFDIKENA VETLKKIQNI PSVEVGVVYN DKNEIFAEFY KSGEKIDIPK PKGNSTWNKF
ENDYLDVSHP IFFDKELAGT IYLKVSTQKL TERIQEHLLT MIGLLLFLII LNYIIATRLQ
KVLSEPILNL TKATKKISEE GNYQLRVQKQ GNDEIGVLVD EYNEMLNQIH EREEALKLRT
NELSEALIDL EETQEKLINS EKLAALGQLI SGVAHEINTP LGAINSSIGS IKKSLIFVLE
SYPKFINKLP IELKNSFLNL LEESFKNKKV LTSREEREFK KEITITLEKH KIENAYTLAD
SFVDMMVLDN VEDYLELLKR DDAEQIIDVA YKITGLQRST FNVEFAASKA SKVVYALKNL
SRIGSNEELV LANVCDGIDN VLILYSNQIK QGIEVSKKYE ELPQILCYSD ELNQVWTNIL
HNAIYAMDLN GKLTIKAYKE KEHIVVAITD SGKGIPKEEM DKIFNPFYTT KPIGEGTGLG
LDISKRIVEK HKGRIEVESI PGKTTFKVYI PIKQEK
//
