ID A0A1H3S915_9PSEU Unreviewed; 575 AA.
AC A0A1H3S915;
DT 22-NOV-2017, integrated into UniProtKB/TrEMBL.
DT 22-NOV-2017, sequence version 1.
DT 28-JAN-2026, entry version 28.
DE SubName: Full=Selenocysteine-specific elongation factor {ECO:0000313|EMBL:SDZ34472.1};
GN ORFNames=SAMN05421504_11346 {ECO:0000313|EMBL:SDZ34472.1};
OS Amycolatopsis xylanica.
OC Bacteria; Bacillati; Actinomycetota; Actinomycetes; Pseudonocardiales;
OC Pseudonocardiaceae; Amycolatopsis.
OX NCBI_TaxID=589385 {ECO:0000313|EMBL:SDZ34472.1, ECO:0000313|Proteomes:UP000199515};
RN [1] {ECO:0000313|EMBL:SDZ34472.1, ECO:0000313|Proteomes:UP000199515}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=CPCC 202699 {ECO:0000313|EMBL:SDZ34472.1,
RC ECO:0000313|Proteomes:UP000199515};
RA de Groot N.N.;
RL Submitted (OCT-2016) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000256|ARBA:ARBA00004496}.
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DR EMBL; FNON01000013; SDZ34472.1; -; Genomic_DNA.
DR RefSeq; WP_091298809.1; NZ_FNON01000013.1.
DR AlphaFoldDB; A0A1H3S915; -.
DR STRING; 589385.SAMN05421504_11346; -.
DR OrthoDB; 9803139at2; -.
DR Proteomes; UP000199515; Unassembled WGS sequence.
DR GO; GO:0005829; C:cytosol; IEA:TreeGrafter.
DR GO; GO:0005525; F:GTP binding; IEA:UniProtKB-KW.
DR GO; GO:0003924; F:GTPase activity; IEA:InterPro.
DR GO; GO:0003723; F:RNA binding; IEA:InterPro.
DR GO; GO:0003746; F:translation elongation factor activity; IEA:UniProtKB-KW.
DR GO; GO:0001514; P:selenocysteine incorporation; IEA:InterPro.
DR CDD; cd04171; SelB; 1.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 1.
DR Gene3D; 2.40.30.10; Translation factors; 1.
DR Gene3D; 1.10.10.10; Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain; 1.
DR InterPro; IPR057335; Beta-barrel_SelB.
DR InterPro; IPR050055; EF-Tu_GTPase.
DR InterPro; IPR027417; P-loop_NTPase.
DR InterPro; IPR015191; SelB_WHD4.
DR InterPro; IPR000795; T_Tr_GTP-bd_dom.
DR InterPro; IPR009000; Transl_B-barrel_sf.
DR InterPro; IPR004535; Transl_elong_SelB.
DR InterPro; IPR036388; WH-like_DNA-bd_sf.
DR NCBIfam; TIGR00475; selB; 1.
DR PANTHER; PTHR43721:SF22; ELONGATION FACTOR TU, MITOCHONDRIAL; 1.
DR PANTHER; PTHR43721; ELONGATION FACTOR TU-RELATED; 1.
DR Pfam; PF25461; Beta-barrel_SelB; 1.
DR Pfam; PF00009; GTP_EFTU; 1.
DR Pfam; PF09107; WHD_3rd_SelB; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR SUPFAM; SSF50447; Translation proteins; 1.
DR PROSITE; PS51722; G_TR_2; 1.
PE 4: Predicted;
KW Cytoplasm {ECO:0000256|ARBA:ARBA00022490};
KW Elongation factor {ECO:0000313|EMBL:SDZ34472.1};
KW GTP-binding {ECO:0000256|ARBA:ARBA00023134};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00023134};
KW Protein biosynthesis {ECO:0000256|ARBA:ARBA00022917};
KW Reference proteome {ECO:0000313|Proteomes:UP000199515}.
FT DOMAIN 1..169
FT /note="Tr-type G"
FT /evidence="ECO:0000259|PROSITE:PS51722"
SQ SEQUENCE 575 AA; 60882 MW; 114F3F9AE83F9950 CRC64;
MRVIATAGHF DHGKSTLIRR LTGMEPDRWA EERRRGLTID LGFAWTRIGG EEFAFVDVPG
HERFVPNMLA GAGPVPAVLF VVAADEGWMP QSAEHLAALD AFGVEHGLLV VTKADRADPA
AATAQASREI AATSLGEVAS VHVSGTTGQG LDELRAALEA VTATMPRPDT GADVRLWIDR
AFTVRGAGTV VTGTLAEGTI ATGDELDLGG TRVKVRGLQA LGQARDRVEG VARVAVNLRG
TPRGDAGRGD VLLTPGAWLG TAEIDVRLRP AAELPRELVL HLGAAAVPAR VRPLGKDAAR
LTLARPLPVR VGDRGLLRDP GAHRISAGIS VLDVRPPSLT RRGAAKARAE ELAEPDLPRD
YLRRNGFVPV TEFRAMGLPE VGERIGDWLA DPGRVARLRA EVPGVVAAWS RDHAVAAGMP
VETLRRLLDL PSLDLVAPLL RDTGLELAGG LVSAPGAGLG PAVDRAVRAL EERFGTRPFH
APEADELREL GLGRKELAAA VRLGRLTAIA DGVVLGPRAE ERAAAALAGV DQPFTVSQAR
RALDSTRRVM IPLLERLDAL GLTEPRPDGT RHTTS
//
