ID A0A1H9Z233_9FIRM Unreviewed; 378 AA.
AC A0A1H9Z233;
DT 22-NOV-2017, integrated into UniProtKB/TrEMBL.
DT 22-NOV-2017, sequence version 1.
DT 08-OCT-2025, entry version 24.
DE SubName: Full=Cell wall-associated hydrolase, NlpC family {ECO:0000313|EMBL:SES75543.1};
GN ORFNames=SAMN05660297_00514 {ECO:0000313|EMBL:SES75543.1};
OS Natronincola peptidivorans.
OC Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
OC Natronincolaceae; Natronincola.
OX NCBI_TaxID=426128 {ECO:0000313|EMBL:SES75543.1, ECO:0000313|Proteomes:UP000199568};
RN [1] {ECO:0000313|EMBL:SES75543.1, ECO:0000313|Proteomes:UP000199568}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=DSM 18979 {ECO:0000313|EMBL:SES75543.1,
RC ECO:0000313|Proteomes:UP000199568};
RA de Groot N.N.;
RL Submitted (OCT-2016) to the EMBL/GenBank/DDBJ databases.
CC -!- SIMILARITY: Belongs to the peptidase C40 family.
CC {ECO:0000256|ARBA:ARBA00007074}.
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DR EMBL; FOHU01000001; SES75543.1; -; Genomic_DNA.
DR RefSeq; WP_090438787.1; NZ_FOHU01000001.1.
DR AlphaFoldDB; A0A1H9Z233; -.
DR STRING; 426128.SAMN05660297_00514; -.
DR OrthoDB; 9808890at2; -.
DR Proteomes; UP000199568; Unassembled WGS sequence.
DR GO; GO:0008234; F:cysteine-type peptidase activity; IEA:UniProtKB-KW.
DR Gene3D; 3.90.1720.10; endopeptidase domain like (from Nostoc punctiforme); 1.
DR Gene3D; 2.30.30.40; SH3 Domains; 3.
DR InterPro; IPR000064; NLP_P60_dom.
DR InterPro; IPR038765; Papain-like_cys_pep_sf.
DR InterPro; IPR051202; Peptidase_C40.
DR InterPro; IPR003646; SH3-like_bac-type.
DR PANTHER; PTHR47053; MUREIN DD-ENDOPEPTIDASE MEPH-RELATED; 1.
DR PANTHER; PTHR47053:SF1; MUREIN DD-ENDOPEPTIDASE MEPH-RELATED; 1.
DR Pfam; PF00877; NLPC_P60; 1.
DR Pfam; PF08239; SH3_3; 1.
DR SMART; SM00287; SH3b; 2.
DR SUPFAM; SSF54001; Cysteine proteinases; 1.
DR PROSITE; PS51935; NLPC_P60; 1.
DR PROSITE; PS51781; SH3B; 1.
PE 3: Inferred from homology;
KW Hydrolase {ECO:0000256|ARBA:ARBA00022801, ECO:0000313|EMBL:SES75543.1};
KW Protease {ECO:0000256|ARBA:ARBA00022670};
KW Reference proteome {ECO:0000313|Proteomes:UP000199568};
KW Thiol protease {ECO:0000256|ARBA:ARBA00022807}.
FT DOMAIN 101..165
FT /note="SH3b"
FT /evidence="ECO:0000259|PROSITE:PS51781"
FT DOMAIN 243..378
FT /note="NlpC/P60"
FT /evidence="ECO:0000259|PROSITE:PS51935"
SQ SEQUENCE 378 AA; 42416 MW; 91EE8996913D5ACA CRC64;
MKRLKISKIP VVLSIVLVII FISTSTALAD GKLAMVIANQ GILREKPEVE GKVIQLPSIG
TEVLIRETKN NWNKVVLVDN GVQGWMHEDF LAITGEESKP IKKGIVNVNN VLNLRSTPST
SGSILSQLRN GTELIVLNQA NEWYEIQLKE GTKGFVHSDF ILLIPNYPHG IIVENNSKIK
EKANNESKTI ITLSKNDDIY IKKYMDGWYN VLTKDFQEGW LKSDSVDLQI NIGSPVSRSG
TRSHPLSNIK EHTEKYLGKP YRYAATGPNN FDCSGFVYYV LNKYYPDYLR DKGIKLQRTS
RDQATMGTPI NKNELQIGDL VFFNNGRSST ISHVGIYIGN DEFIHSSSTN NRGIIISSLK
DGPASWSYQS RYVSAVRL
//
