ID   A0A1I4TLS4_9GAMM        Unreviewed;       627 AA.
AC   A0A1I4TLS4;
DT   05-DEC-2018, integrated into UniProtKB/TrEMBL.
DT   05-DEC-2018, sequence version 1.
DT   28-JAN-2026, entry version 26.
DE   SubName: Full=Selenocysteine-specific elongation factor {ECO:0000313|EMBL:SFM77718.1};
GN   ORFNames=SAMN05216217_11510 {ECO:0000313|EMBL:SFM77718.1};
OS   Halopseudomonas yangmingensis.
OC   Bacteria; Pseudomonadati; Pseudomonadota; Gammaproteobacteria;
OC   Pseudomonadales; Pseudomonadaceae; Halopseudomonas.
OX   NCBI_TaxID=1720063 {ECO:0000313|EMBL:SFM77718.1, ECO:0000313|Proteomes:UP000243629};
RN   [1] {ECO:0000313|Proteomes:UP000243629}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=DSM 24213 {ECO:0000313|Proteomes:UP000243629};
RA   Varghese N., Submissions S.;
RL   Submitted (OCT-2016) to the EMBL/GenBank/DDBJ databases.
CC   -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000256|ARBA:ARBA00004496}.
CC   ---------------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC   ---------------------------------------------------------------------------
DR   EMBL; FOUI01000015; SFM77718.1; -; Genomic_DNA.
DR   RefSeq; WP_177197284.1; NZ_FOUI01000015.1.
DR   AlphaFoldDB; A0A1I4TLS4; -.
DR   STRING; 1720063.SAMN05216217_11510; -.
DR   Proteomes; UP000243629; Unassembled WGS sequence.
DR   GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR   GO; GO:0005525; F:GTP binding; IEA:UniProtKB-KW.
DR   GO; GO:0003924; F:GTPase activity; IEA:InterPro.
DR   GO; GO:0003723; F:RNA binding; IEA:InterPro.
DR   GO; GO:0003746; F:translation elongation factor activity; IEA:UniProtKB-KW.
DR   GO; GO:0001514; P:selenocysteine incorporation; IEA:InterPro.
DR   CDD; cd04171; SelB; 1.
DR   CDD; cd15491; selB_III; 1.
DR   Gene3D; 1.10.10.2770; -; 1.
DR   Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 1.
DR   Gene3D; 2.40.30.10; Translation factors; 1.
DR   Gene3D; 1.10.10.10; Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain; 1.
DR   InterPro; IPR057335; Beta-barrel_SelB.
DR   InterPro; IPR050055; EF-Tu_GTPase.
DR   InterPro; IPR015190; Elong_fac_SelB-wing-hlx_typ-2.
DR   InterPro; IPR027417; P-loop_NTPase.
DR   InterPro; IPR015191; SelB_WHD4.
DR   InterPro; IPR000795; T_Tr_GTP-bd_dom.
DR   InterPro; IPR009000; Transl_B-barrel_sf.
DR   InterPro; IPR009001; Transl_elong_EF1A/Init_IF2_C.
DR   InterPro; IPR004535; Transl_elong_SelB.
DR   InterPro; IPR036388; WH-like_DNA-bd_sf.
DR   InterPro; IPR036390; WH_DNA-bd_sf.
DR   NCBIfam; TIGR00475; selB; 1.
DR   PANTHER; PTHR43721:SF22; ELONGATION FACTOR TU, MITOCHONDRIAL; 1.
DR   PANTHER; PTHR43721; ELONGATION FACTOR TU-RELATED; 1.
DR   Pfam; PF25461; Beta-barrel_SelB; 1.
DR   Pfam; PF00009; GTP_EFTU; 1.
DR   Pfam; PF09106; WHD_2nd_SelB; 1.
DR   Pfam; PF09107; WHD_3rd_SelB; 1.
DR   PRINTS; PR00315; ELONGATNFCT.
DR   SUPFAM; SSF50465; EF-Tu/eEF-1alpha/eIF2-gamma C-terminal domain; 1.
DR   SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR   SUPFAM; SSF50447; Translation proteins; 1.
DR   SUPFAM; SSF46785; Winged helix' DNA-binding domain; 3.
DR   PROSITE; PS51722; G_TR_2; 1.
PE   4: Predicted;
KW   Cytoplasm {ECO:0000256|ARBA:ARBA00022490};
KW   Elongation factor {ECO:0000313|EMBL:SFM77718.1};
KW   GTP-binding {ECO:0000256|ARBA:ARBA00023134};
KW   Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741};
KW   Protein biosynthesis {ECO:0000256|ARBA:ARBA00022917};
KW   Reference proteome {ECO:0000313|Proteomes:UP000243629}.
FT   DOMAIN          1..172
FT                   /note="Tr-type G"
FT                   /evidence="ECO:0000259|PROSITE:PS51722"
SQ   SEQUENCE   627 AA;  68624 MW;  0A435ED4273C7108 CRC64;
     MIIASAGHVD HGKTSLIRAL TGVDTDRLAE EKRRGMSIEL GFAWLDNGEH EPLGFVDVPG
     HERFIGTMLA GVAAVDMALL VVAADAGPMP QTLEHLSILR LLGVQRLLLV LSRCDLVEPA
     RQQQLGEELA EWLEQQGWPA VPQFAVSSVS GAGIDALRQY LLDCASNHQR PPSQGPARLL
     VDRRFSIAGA GCVVTGSLHS GRLQVGQNLL CGQRSLRVRG LQMAGREAAV VEAGQRCAVN
     LAGDLRDDQP RRGDWLGSLP QAFSNRLDVA LHSLPDSRWH RGVLQLHLGA AVHPARLVLL
     EEGQPVLAQL LLEQPLHALH GDRFIIRDPA ANRTLGGGRV LDPQGQQRGR SKAPRLQLLR
     AWAQADSPQQ ALLAALQQGP LELHGFAERF NLTLAELQQW LASDAALDGQ DAPVLLQAGK
     HSWALHCHQA EAIWQVLQQH LQAWHAAHPE RLGPGEGELG LAGTLHLPLS LWRALLRHWL
     DQGRLGRQAW AWHLPQHQPQ LQAADQQLLE RLRPLLLEGG LRPPIVGELS QLLGIELAEL
     KLFLQRMQRA GQLIAVAPNR YYLPQQVDGL VALARQLVAD SASGSFNAAE FRDASGIGRN
     LTIQVLEYLD RAGVTRFLRE QRFLAGG
//