ID A0A1I5NZ86_9BACT Unreviewed; 412 AA.
AC A0A1I5NZ86;
DT 22-NOV-2017, integrated into UniProtKB/TrEMBL.
DT 22-NOV-2017, sequence version 1.
DT 02-APR-2025, entry version 21.
DE SubName: Full=Concentrative nucleoside transporter, CNT family {ECO:0000313|EMBL:SFP26930.1};
GN ORFNames=SAMN04515674_102184 {ECO:0000313|EMBL:SFP26930.1};
OS Pseudarcicella hirudinis.
OC Bacteria; Pseudomonadati; Bacteroidota; Cytophagia; Cytophagales;
OC Flectobacillaceae; Pseudarcicella.
OX NCBI_TaxID=1079859 {ECO:0000313|EMBL:SFP26930.1, ECO:0000313|Proteomes:UP000199306};
RN [1] {ECO:0000313|EMBL:SFP26930.1, ECO:0000313|Proteomes:UP000199306}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=E92,LMG 26720,CCM 7988 {ECO:0000313|Proteomes:UP000199306};
RA de Groot N.N.;
RL Submitted (OCT-2016) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBCELLULAR LOCATION: Cell membrane {ECO:0000256|ARBA:ARBA00004651};
CC Multi-pass membrane protein {ECO:0000256|ARBA:ARBA00004651}.
CC -!- SIMILARITY: Belongs to the concentrative nucleoside transporter (CNT)
CC (TC 2.A.41) family. {ECO:0000256|ARBA:ARBA00009033}.
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DR EMBL; FOXH01000002; SFP26930.1; -; Genomic_DNA.
DR RefSeq; WP_092012561.1; NZ_FOXH01000002.1.
DR AlphaFoldDB; A0A1I5NZ86; -.
DR STRING; 1079859.SAMN04515674_102184; -.
DR OrthoDB; 9766455at2; -.
DR Proteomes; UP000199306; Unassembled WGS sequence.
DR GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0005337; F:nucleoside transmembrane transporter activity; IEA:InterPro.
DR GO; GO:0015293; F:symporter activity; IEA:TreeGrafter.
DR InterPro; IPR008276; C_nuclsd_transpt.
DR InterPro; IPR011657; CNT_C_dom.
DR InterPro; IPR002668; CNT_N_dom.
DR InterPro; IPR011642; Gate_dom.
DR PANTHER; PTHR10590; SODIUM/NUCLEOSIDE COTRANSPORTER; 1.
DR PANTHER; PTHR10590:SF4; SOLUTE CARRIER FAMILY 28 MEMBER 3; 1.
DR Pfam; PF07670; Gate; 1.
DR Pfam; PF07662; Nucleos_tra2_C; 1.
DR Pfam; PF01773; Nucleos_tra2_N; 1.
PE 3: Inferred from homology;
KW Cell membrane {ECO:0000256|ARBA:ARBA00022475};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000199306};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}.
FT TRANSMEM 97..121
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 133..154
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 175..197
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 203..223
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 260..282
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 288..309
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 352..379
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 391..411
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 8..81
FT /note="Concentrative nucleoside transporter N-terminal"
FT /evidence="ECO:0000259|Pfam:PF01773"
FT DOMAIN 100..198
FT /note="Nucleoside transporter/FeoB GTPase Gate"
FT /evidence="ECO:0000259|Pfam:PF07670"
FT DOMAIN 203..409
FT /note="Concentrative nucleoside transporter C-terminal"
FT /evidence="ECO:0000259|Pfam:PF07662"
SQ SEQUENCE 412 AA; 43414 MW; 045D1C64DA1FE762 CRC64;
MERFTGLLGI VLILGLAYLM SNNRKAINFR TVGVGLALQA GLAVFILKTD VGQAIFQWLG
FKINSILLNA DKGAEFVFGS LVKPELMVKA FGSGNDFVFF FKVIPTIIFV AVLVNMFYHL
GVLQRVVSVL GRGVHWLMGV SGAEALSNVA STFVGQVEAQ IMIKPYLKTM TNSELLASMT
GSFACIAGGV MAVYISLGVP ASYLLAASLM AAPGALVISK IVYPETEQSE TQGLVKLEIK
KTHANLVDAI AAGASEGLKV GLNVIAMLIG FIALIALVDV ILGRVGGLVG FPALSLNFIL
GKFFSIFAWC MGVPGKDVQA AGALMGTKMV VNEFVAYLEL VKLKPNLDPK TIAITSFALC
GFANFSSVAI QIGGIGELAP SRRSDLAKLG FKALICGTLA SYLSATLAGL LL
//
