ID A0A1I6CDS5_9BACI Unreviewed; 392 AA.
AC A0A1I6CDS5;
DT 22-NOV-2017, integrated into UniProtKB/TrEMBL.
DT 22-NOV-2017, sequence version 1.
DT 02-APR-2025, entry version 18.
DE SubName: Full=Nucleoside transport protein {ECO:0000313|EMBL:SFQ91340.1};
GN ORFNames=SAMN04488577_0027 {ECO:0000313|EMBL:SFQ91340.1};
OS Bacillus sp. cl95.
OC Bacteria; Bacillati; Bacillota; Bacilli; Bacillales; Bacillaceae; Bacillus.
OX NCBI_TaxID=1761761 {ECO:0000313|EMBL:SFQ91340.1, ECO:0000313|Proteomes:UP000199578};
RN [1] {ECO:0000313|EMBL:SFQ91340.1, ECO:0000313|Proteomes:UP000199578}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=CL95 {ECO:0000313|EMBL:SFQ91340.1,
RC ECO:0000313|Proteomes:UP000199578};
RA de Groot N.N.;
RL Submitted (OCT-2016) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBCELLULAR LOCATION: Cell membrane {ECO:0000256|ARBA:ARBA00004651};
CC Multi-pass membrane protein {ECO:0000256|ARBA:ARBA00004651}.
CC -!- SIMILARITY: Belongs to the concentrative nucleoside transporter (CNT)
CC (TC 2.A.41) family. {ECO:0000256|ARBA:ARBA00009033}.
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DR EMBL; FOYF01000010; SFQ91340.1; -; Genomic_DNA.
DR RefSeq; WP_090833460.1; NZ_FOYF01000010.1.
DR AlphaFoldDB; A0A1I6CDS5; -.
DR STRING; 1761761.SAMN04488577_0027; -.
DR OrthoDB; 9766455at2; -.
DR Proteomes; UP000199578; Unassembled WGS sequence.
DR GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0005337; F:nucleoside transmembrane transporter activity; IEA:InterPro.
DR GO; GO:0015293; F:symporter activity; IEA:TreeGrafter.
DR InterPro; IPR008276; C_nuclsd_transpt.
DR InterPro; IPR011657; CNT_C_dom.
DR InterPro; IPR002668; CNT_N_dom.
DR InterPro; IPR011642; Gate_dom.
DR PANTHER; PTHR10590:SF23; NUPC_NUPG FAMILY NUCLEOSIDE CNT TRANSPORTER; 1.
DR PANTHER; PTHR10590; SODIUM/NUCLEOSIDE COTRANSPORTER; 1.
DR Pfam; PF07670; Gate; 1.
DR Pfam; PF07662; Nucleos_tra2_C; 1.
DR Pfam; PF01773; Nucleos_tra2_N; 1.
PE 3: Inferred from homology;
KW Cell membrane {ECO:0000256|ARBA:ARBA00022475};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000199578};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}.
FT TRANSMEM 31..54
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 89..110
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 165..186
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 192..211
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 246..268
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 280..306
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 327..353
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 373..391
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 9..81
FT /note="Concentrative nucleoside transporter N-terminal"
FT /evidence="ECO:0000259|Pfam:PF01773"
FT DOMAIN 90..190
FT /note="Nucleoside transporter/FeoB GTPase Gate"
FT /evidence="ECO:0000259|Pfam:PF07670"
FT DOMAIN 192..389
FT /note="Concentrative nucleoside transporter C-terminal"
FT /evidence="ECO:0000259|Pfam:PF07662"
SQ SEQUENCE 392 AA; 42339 MW; 1AD247B63936828D CRC64;
MKYLLFLVAL ALIFVLAFVA SNDKKKIKFK PIAIMLVLQL VLTFLLLNTG IGLIIIKAIS
RLFDRLLAFA AEGVNFVFGG LANEGAMSFF LNVLLPIVFI SVLIGIAQHL RILPVIIKGL
GLVLSKINGL GRLESYNAVA SAVFGQSEVF ISVKKQLGHL PERRLYTLCT SAMSTVSASI
LGAYMTMIDP KYVITALVLN LFGGFIIANI INPYEVSAEE DNIEIQQEKQ TFFEMLGEYI
MDGFKVAIIV GAMLIGFVGL IAMINFVFDL IFGMSFQTLI GYVFAPLAFI IGVPWSEAVS
AGTIMATKLV SNEFVAMMDL AKITGDLSAR TIGIISVFLV SFANFSSIGI ITGAVKGLNE
EKGNVVARFG LKLLYGATLV SLLSAAIIGI ML
//
