ID A0A1I6M834_9EURY Unreviewed; 1826 AA.
AC A0A1I6M834;
DT 22-NOV-2017, integrated into UniProtKB/TrEMBL.
DT 22-NOV-2017, sequence version 1.
DT 02-APR-2025, entry version 28.
DE RecName: Full=histidine kinase {ECO:0000256|ARBA:ARBA00012438};
DE EC=2.7.13.3 {ECO:0000256|ARBA:ARBA00012438};
GN ORFNames=SAMN05216559_3945 {ECO:0000313|EMBL:SFS11793.1};
OS Halomicrobium zhouii.
OC Archaea; Methanobacteriati; Methanobacteriota; Stenosarchaea group;
OC Halobacteria; Halobacteriales; Haloarculaceae; Halomicrobium.
OX NCBI_TaxID=767519 {ECO:0000313|EMBL:SFS11793.1, ECO:0000313|Proteomes:UP000199062};
RN [1] {ECO:0000313|EMBL:SFS11793.1, ECO:0000313|Proteomes:UP000199062}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=CGMCC 1.10457 {ECO:0000313|EMBL:SFS11793.1,
RC ECO:0000313|Proteomes:UP000199062};
RA de Groot N.N.;
RL Submitted (OCT-2016) to the EMBL/GenBank/DDBJ databases.
CC -!- CATALYTIC ACTIVITY:
CC Reaction=ATP + protein L-histidine = ADP + protein N-phospho-L-
CC histidine.; EC=2.7.13.3; Evidence={ECO:0000256|ARBA:ARBA00000085};
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DR EMBL; FOZK01000005; SFS11793.1; -; Genomic_DNA.
DR RefSeq; WP_089818948.1; NZ_FOZK01000005.1.
DR STRING; 767519.SAMN05216559_3945; -.
DR OrthoDB; 165911at2157; -.
DR Proteomes; UP000199062; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR GO; GO:0016301; F:kinase activity; IEA:UniProtKB-KW.
DR GO; GO:0006355; P:regulation of DNA-templated transcription; IEA:InterPro.
DR CDD; cd00130; PAS; 8.
DR Gene3D; 2.10.70.100; -; 2.
DR Gene3D; 3.30.450.40; -; 2.
DR Gene3D; 3.30.450.20; PAS domain; 9.
DR Gene3D; 1.10.10.10; Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain; 1.
DR InterPro; IPR031803; BAT_GAF/HTH-assoc.
DR InterPro; IPR003018; GAF.
DR InterPro; IPR029016; GAF-like_dom_sf.
DR InterPro; IPR007050; HTH_bacterioopsin.
DR InterPro; IPR001610; PAC.
DR InterPro; IPR000014; PAS.
DR InterPro; IPR000700; PAS-assoc_C.
DR InterPro; IPR035965; PAS-like_dom_sf.
DR InterPro; IPR013656; PAS_4.
DR InterPro; IPR013767; PAS_fold.
DR InterPro; IPR013655; PAS_fold_3.
DR InterPro; IPR013324; RNA_pol_sigma_r3/r4-like.
DR InterPro; IPR052162; Sensor_kinase/Photoreceptor.
DR InterPro; IPR036388; WH-like_DNA-bd_sf.
DR NCBIfam; TIGR00229; sensory_box; 7.
DR PANTHER; PTHR43304:SF1; PAC DOMAIN-CONTAINING PROTEIN; 1.
DR PANTHER; PTHR43304; PHYTOCHROME-LIKE PROTEIN CPH1; 1.
DR Pfam; PF15915; BAT; 1.
DR Pfam; PF13185; GAF_2; 2.
DR Pfam; PF04967; HTH_10; 1.
DR Pfam; PF00989; PAS; 2.
DR Pfam; PF08447; PAS_3; 3.
DR Pfam; PF08448; PAS_4; 4.
DR SMART; SM00086; PAC; 9.
DR SMART; SM00091; PAS; 7.
DR SUPFAM; SSF55781; GAF domain-like; 2.
DR SUPFAM; SSF55785; PYP-like sensor domain (PAS domain); 9.
DR SUPFAM; SSF88659; Sigma3 and sigma4 domains of RNA polymerase sigma factors; 1.
DR PROSITE; PS50113; PAC; 9.
DR PROSITE; PS50112; PAS; 7.
PE 4: Predicted;
KW Kinase {ECO:0000256|ARBA:ARBA00022777}; Membrane {ECO:0000256|SAM:Phobius};
KW Phosphoprotein {ECO:0000256|ARBA:ARBA00022553};
KW Reference proteome {ECO:0000313|Proteomes:UP000199062};
KW Transcription {ECO:0000256|ARBA:ARBA00023163};
KW Transcription regulation {ECO:0000256|ARBA:ARBA00023015};
KW Transferase {ECO:0000256|ARBA:ARBA00022679};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT TRANSMEM 21..41
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 131..201
FT /note="PAS"
FT /evidence="ECO:0000259|PROSITE:PS50112"
FT DOMAIN 203..254
FT /note="PAC"
FT /evidence="ECO:0000259|PROSITE:PS50113"
FT DOMAIN 324..379
FT /note="PAC"
FT /evidence="ECO:0000259|PROSITE:PS50113"
FT DOMAIN 380..452
FT /note="PAS"
FT /evidence="ECO:0000259|PROSITE:PS50112"
FT DOMAIN 455..506
FT /note="PAC"
FT /evidence="ECO:0000259|PROSITE:PS50113"
FT DOMAIN 507..577
FT /note="PAS"
FT /evidence="ECO:0000259|PROSITE:PS50112"
FT DOMAIN 579..630
FT /note="PAC"
FT /evidence="ECO:0000259|PROSITE:PS50113"
FT DOMAIN 701..753
FT /note="PAC"
FT /evidence="ECO:0000259|PROSITE:PS50113"
FT DOMAIN 783..827
FT /note="PAS"
FT /evidence="ECO:0000259|PROSITE:PS50112"
FT DOMAIN 830..881
FT /note="PAC"
FT /evidence="ECO:0000259|PROSITE:PS50113"
FT DOMAIN 882..927
FT /note="PAS"
FT /evidence="ECO:0000259|PROSITE:PS50112"
FT DOMAIN 953..1005
FT /note="PAC"
FT /evidence="ECO:0000259|PROSITE:PS50113"
FT DOMAIN 1006..1075
FT /note="PAS"
FT /evidence="ECO:0000259|PROSITE:PS50112"
FT DOMAIN 1078..1130
FT /note="PAC"
FT /evidence="ECO:0000259|PROSITE:PS50113"
FT DOMAIN 1131..1204
FT /note="PAS"
FT /evidence="ECO:0000259|PROSITE:PS50112"
FT DOMAIN 1207..1258
FT /note="PAC"
FT /evidence="ECO:0000259|PROSITE:PS50113"
SQ SEQUENCE 1826 AA; 203823 MW; AAD1C3FBF1BB08E4 CRC64;
MTASWGVVPA TDRWRHRWNR VHAWFVLSVA FCVAVSVGIV GDPAVFGSPG GPGQVLVGFV
GLAVAGGDDD DDAVADLLDR IERFEDGEDV DFESDREDDI GLLYDAVGSL ADRAGGSDRR
TGGAGRELER HATATDDALD AVEDVFAVID EDGYPQRWNE RLADVLGYDD AEMASTHVLE
WFPADDHRTV EGAIRAASET GSVRVEAPLT TVDGEQTTYE FVASALEDAD GNPVVAAIGR
DVSERTAREA ELERQASLLD SLFERLPVSL YVKDREGRHV RTSIPYHREQ YPDDEEWFIG
KTDPEIYDSE LAAETHADDR RVIEEGEPIV EKVEFDPADE EWLLTSKVPW RDEDGDVRGL
IGISQYVTEQ KERERELRET KRKLELTLEG TRTGIYDWNM ETNEVDWSET FERMLGLEPG
TFEGTYDDFE RRVHPDDVSR IDAAVDRALE NDELFLTEFR LRHEDGRWIW VNARGWVVVD
EEGHRRMVGI NHDITERKER EQQLQRYKEY TDDILDALDD VFYVLDSNGN LQRWNESMSE
VTGYTDDELR GKQALEFFSE QDVEAVSAAI EEVFETGNTR IEVEALTKDG RSIPYELVAA
RLEDPEGNQV LAGIGRDVSE RRRLEQDLRT EKEHFRVALE NSPLVAFRQD TDLRYTWVGN
PQRDFRDHEV IGKRDDEIFP PQSAETLTEI KRSALETGDA VREEVTYELP SGEEVTYDLT
VEPFRNESGE IVGLTIAALD ITERREREAE IERTTDLLEQ AGRIARIGGW ELDLTTDPPE
MTWTDELYDI HGVEPGTPVD VETVVDRYHP EDREYIENRL EAAIERGESY DMEVRIQSGS
DQHRWVRALG EAVSEDGEVV KLRGSIQDIT EQKEREAELR ATKNRMQKFI ETSPVGVVGT
TPEGIVTLWN DAMEQIFGWS AEEVLGEPYP AISDGDDDPD PVRQRVLDGE AISQVELERV
TKDGEQIDVS LSTGPVYDAA GDISEVVGYI EDITERKERE RELQETNERL NAVIDASPDA
IVALDTDGTV TLWNPAAERI FGWREDEILG EPMPIVPPER AEEHADILRR LADGETVRGA
EVLRQTRDGE RIELSLSAAP LRDADGTIVG NLGVSEDISR RKERQRELER TKDMLAQAQQ
LAAVGGWELD LAGDEPVLEW TDELYRIHGL PPGADVTLDE ALDFYHTEDR PRIRDAIDRV
VETGGTYDEE TRFYAADGEQ RWVRAIGKAI QQDGETVKLR GAFQDITRQK ERELALQSLH
DATRGLLHTE SETEVAELVV ETAAELFDVS GVAVYTIDDA SNRLVPAAYT DAFDALSDGA
PSVGVGDDAA VWNCFATGER VVFDDAETAR QSRVFGESVD GGLLVPMGDH GVFVVATDGP
RIDDDTRRLA ETLVATTEAA FDRLASEADL RKRDEELEAQ NRRLRRQIQI NDIIRRVDQS
LVGATSREEV ESAVCDRLVE SDDVAFAWIG GFDGDGDELV PRAWAGPGQT YLDTLALDDL
KDSTEPSLAT ARSGEATVVG NVVDRLREDA WRRGALANDF HSVISVPLAV DEYSHGALTV
YAGEPDTFGD LERTVFAELG RSIANAINAV SAREALHADT VVELTLRFDD PNGVLSRVAR
DADCDVEYEG ISTRSADETR LFFATTGAAA DAVADVLEGL YAVTECRLVS ESDDGRCLFE
VTVTGTVLPS ALVDQGASPR SIRATPIGTE VVVDLPTSTD VREFVETLGE EFPSVELAGR
RNVERGMGTR QQLLSSLLGE LTDRQLEVLR TAYFAGFFEW PRQSTGEEVA EMLDVTQPTV
NRHLRLGQQR LLAQLFDEEA PDLVAA
//
