ID A0A1I6SUI0_9ACTN Unreviewed; 330 AA.
AC A0A1I6SUI0;
DT 22-NOV-2017, integrated into UniProtKB/TrEMBL.
DT 22-NOV-2017, sequence version 1.
DT 05-FEB-2025, entry version 16.
DE SubName: Full=2-dehydropantoate 2-reductase {ECO:0000313|EMBL:SFS80576.1};
GN ORFNames=SAMN05444716_104159 {ECO:0000313|EMBL:SFS80576.1};
OS Streptomyces harbinensis.
OC Bacteria; Bacillati; Actinomycetota; Actinomycetes; Kitasatosporales;
OC Streptomycetaceae; Streptomyces.
OX NCBI_TaxID=1176198 {ECO:0000313|EMBL:SFS80576.1, ECO:0000313|Proteomes:UP000198873};
RN [1] {ECO:0000313|Proteomes:UP000198873}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=CGMCC 4.7047 {ECO:0000313|Proteomes:UP000198873};
RA Varghese N., Submissions S.;
RL Submitted (OCT-2016) to the EMBL/GenBank/DDBJ databases.
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DR EMBL; FPAB01000004; SFS80576.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A1I6SUI0; -.
DR STRING; 1176198.SAMN05444716_104159; -.
DR Proteomes; UP000198873; Unassembled WGS sequence.
DR GO; GO:0005737; C:cytoplasm; IEA:TreeGrafter.
DR Gene3D; 1.10.1040.10; N-(1-d-carboxylethyl)-l-norvaline Dehydrogenase, domain 2; 1.
DR Gene3D; 3.40.50.720; NAD(P)-binding Rossmann-like Domain; 1.
DR InterPro; IPR008927; 6-PGluconate_DH-like_C_sf.
DR InterPro; IPR013328; 6PGD_dom2.
DR InterPro; IPR013752; KPA_reductase.
DR InterPro; IPR051402; KPR-Related.
DR InterPro; IPR013332; KPR_N.
DR InterPro; IPR036291; NAD(P)-bd_dom_sf.
DR PANTHER; PTHR21708:SF26; 2-DEHYDROPANTOATE 2-REDUCTASE; 1.
DR PANTHER; PTHR21708; PROBABLE 2-DEHYDROPANTOATE 2-REDUCTASE; 1.
DR Pfam; PF02558; ApbA; 1.
DR Pfam; PF08546; ApbA_C; 1.
DR SUPFAM; SSF48179; 6-phosphogluconate dehydrogenase C-terminal domain-like; 1.
DR SUPFAM; SSF51735; NAD(P)-binding Rossmann-fold domains; 1.
PE 4: Predicted;
KW Reference proteome {ECO:0000313|Proteomes:UP000198873}.
FT DOMAIN 8..147
FT /note="Ketopantoate reductase N-terminal"
FT /evidence="ECO:0000259|Pfam:PF02558"
FT DOMAIN 190..310
FT /note="Ketopantoate reductase C-terminal"
FT /evidence="ECO:0000259|Pfam:PF08546"
SQ SEQUENCE 330 AA; 34916 MW; 18AC31CFAA016969 CRC64;
MMGRMRYIII GAGAVGGAIG GRLHEAGHEV VLVARGAHYA ELRDGGLRLR TPDASLTLPI
PAADRPEAVE LRQDDVLVLA VKTQDTVAAL ESWAGRPVAG GGTAGERLPL LCAQNGVVNE
RLALRRFRYV YGVCVWLPAQ FLAPGVITAP CAPLTGMLHI GRFPDGTDEV ARRVAADLET
AYFLAPVAGD VMRWKYAKLL SNLANAVEAI TGSASEPGSA ELAARARAEG VAVLRAAGIA
FASEEEQAAL RGERMRMRPV PGGDPAHGSS WQSLRRGAGS IEADYLNGEI VQLGRLHGVE
TPVNELLQRT ANRFAREGRA PGSLAAAELR
//
