ID A0A1K0H463_9BASI Unreviewed; 568 AA.
AC A0A1K0H463;
DT 15-FEB-2017, integrated into UniProtKB/TrEMBL.
DT 15-FEB-2017, sequence version 1.
DT 05-FEB-2025, entry version 29.
DE SubName: Full=Related to 2-dehydropantoate 2-reductase {ECO:0000313|EMBL:SAM58951.1};
GN ORFNames=UBRO2_01961 {ECO:0000313|EMBL:SYW77769.1}, UBRO_01137
GN {ECO:0000313|EMBL:SAM58951.1};
OS Ustilago bromivora.
OC Eukaryota; Fungi; Dikarya; Basidiomycota; Ustilaginomycotina;
OC Ustilaginomycetes; Ustilaginales; Ustilaginaceae; Ustilago.
OX NCBI_TaxID=307758 {ECO:0000313|EMBL:SAM58951.1, ECO:0000313|Proteomes:UP000179920};
RN [1] {ECO:0000313|EMBL:SAM58951.1}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=UB2112 {ECO:0000313|EMBL:SAM58951.1};
RA Evans L.H., Alamgir A., Owens N., Weber N.D., Virtaneva K., Barbian K.,
RA Babar A., Rosenke K.;
RL Submitted (APR-2016) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|Proteomes:UP000179920}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=UB2112 {ECO:0000313|Proteomes:UP000179920};
RA Guldener U., Guldener U.;
RL Submitted (APR-2016) to the EMBL/GenBank/DDBJ databases.
RN [3] {ECO:0000313|EMBL:SYW77769.1}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=UB2 {ECO:0000313|EMBL:SYW77769.1};
RA Guldener U.;
RL Submitted (AUG-2018) to the EMBL/GenBank/DDBJ databases.
CC -!- SIMILARITY: Belongs to the ketopantoate reductase family.
CC {ECO:0000256|ARBA:ARBA00007870}.
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DR EMBL; LT558117; SAM58951.1; -; Genomic_DNA.
DR EMBL; ULHB01000028; SYW77769.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A1K0H463; -.
DR OrthoDB; 5160at5257; -.
DR Proteomes; UP000179920; Chromosome i.
DR Proteomes; UP000658997; Unassembled WGS sequence.
DR GO; GO:0005739; C:mitochondrion; IEA:TreeGrafter.
DR GO; GO:0008677; F:2-dehydropantoate 2-reductase activity; IEA:TreeGrafter.
DR GO; GO:0050661; F:NADP binding; IEA:TreeGrafter.
DR Gene3D; 1.10.1040.10; N-(1-d-carboxylethyl)-l-norvaline Dehydrogenase, domain 2; 1.
DR Gene3D; 3.40.50.720; NAD(P)-binding Rossmann-like Domain; 1.
DR InterPro; IPR008927; 6-PGluconate_DH-like_C_sf.
DR InterPro; IPR013328; 6PGD_dom2.
DR InterPro; IPR050838; Ketopantoate_reductase.
DR InterPro; IPR013752; KPA_reductase.
DR InterPro; IPR013332; KPR_N.
DR InterPro; IPR036291; NAD(P)-bd_dom_sf.
DR PANTHER; PTHR43765:SF2; 2-DEHYDROPANTOATE 2-REDUCTASE; 1.
DR PANTHER; PTHR43765; 2-DEHYDROPANTOATE 2-REDUCTASE-RELATED; 1.
DR Pfam; PF02558; ApbA; 1.
DR Pfam; PF08546; ApbA_C; 1.
DR SUPFAM; SSF48179; 6-phosphogluconate dehydrogenase C-terminal domain-like; 1.
DR SUPFAM; SSF51735; NAD(P)-binding Rossmann-fold domains; 1.
PE 3: Inferred from homology;
KW NADP {ECO:0000256|ARBA:ARBA00022857};
KW Oxidoreductase {ECO:0000256|ARBA:ARBA00023002};
KW Reference proteome {ECO:0000313|Proteomes:UP000658997}.
FT DOMAIN 198..289
FT /note="Ketopantoate reductase N-terminal"
FT /evidence="ECO:0000259|Pfam:PF02558"
FT DOMAIN 393..554
FT /note="Ketopantoate reductase C-terminal"
FT /evidence="ECO:0000259|Pfam:PF08546"
FT REGION 136..182
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 568 AA; 62291 MW; 63279805074FE86D CRC64;
MRYHVLGVGS IGSLIAFHLK RSVKLQRQLL QPRPSFSKSK RELLLSNLSN KRPPQNQGTI
VSSLSLPPYV QTELPDPQQT SVTLHLRRKA FGKQAKQRFV NSIVVEQDGV RDIEGGFQTD
FNSSPTDVIA SIVRRNWSNQ PEGEEEESED RFLISRTTTS SSPEAAAIRD QTSSKTPLPD
HDGGISLIST LEGLHSQPRA SPIDSLIITT KCDATLSALE GIRDRIHPWS TIVLLQNGMG
VLDTLFDTFF KDPDQRPNFV LASTTHGCWR KGPLDVVHAS TGTLHFGIVP SGRAGQDGIE
KSRVPYGQTI ARVRGVVLPS RGEAAKKAAR GWERFSPDTD SNAIEEIPDL GSPSKLLSIA
SIPDKPSLRT LRATVAALLS LPLNVEWEPI REFQLRSLRK LVINACINPL TALADCKNGD
LFGNPVAKDA MWSVCLEAGM VLEAQVREHL ASGATASPRQ RASASLSAED LILRSDETGE
PILHPSLTPQ ALFQEVQRVA RMTAANWSSM HSDLKNRRGS TEIDHINGYI SALGRGYNID
TTANDLLTNL VKLKTTRVTG TGRLRREQ
//
