ID A0A1K2HWF7_9HYPH Unreviewed; 101 AA.
AC A0A1K2HWF7;
DT 15-FEB-2017, integrated into UniProtKB/TrEMBL.
DT 15-FEB-2017, sequence version 1.
DT 18-JUN-2025, entry version 28.
DE RecName: Full=Urease subunit beta {ECO:0000256|HAMAP-Rule:MF_01954};
DE EC=3.5.1.5 {ECO:0000256|HAMAP-Rule:MF_01954};
DE AltName: Full=Urea amidohydrolase subunit beta {ECO:0000256|HAMAP-Rule:MF_01954};
GN Name=ureB {ECO:0000256|HAMAP-Rule:MF_01954};
GN ORFNames=SAMN02983003_1383 {ECO:0000313|EMBL:SFZ82971.1};
OS Devosia enhydra.
OC Bacteria; Pseudomonadati; Pseudomonadota; Alphaproteobacteria;
OC Hyphomicrobiales; Devosiaceae; Devosia.
OX NCBI_TaxID=665118 {ECO:0000313|EMBL:SFZ82971.1, ECO:0000313|Proteomes:UP000183447};
RN [1] {ECO:0000313|EMBL:SFZ82971.1, ECO:0000313|Proteomes:UP000183447}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 23634 {ECO:0000313|EMBL:SFZ82971.1,
RC ECO:0000313|Proteomes:UP000183447};
RA Jaros S., Januszkiewicz K., Wedrychowicz H.;
RL Submitted (NOV-2016) to the EMBL/GenBank/DDBJ databases.
CC -!- CATALYTIC ACTIVITY:
CC Reaction=urea + 2 H2O + H(+) = hydrogencarbonate + 2 NH4(+);
CC Xref=Rhea:RHEA:20557, ChEBI:CHEBI:15377, ChEBI:CHEBI:15378,
CC ChEBI:CHEBI:16199, ChEBI:CHEBI:17544, ChEBI:CHEBI:28938; EC=3.5.1.5;
CC Evidence={ECO:0000256|ARBA:ARBA00047778, ECO:0000256|HAMAP-
CC Rule:MF_01954};
CC -!- PATHWAY: Nitrogen metabolism; urea degradation; CO(2) and NH(3) from
CC urea (urease route): step 1/1. {ECO:0000256|HAMAP-Rule:MF_01954}.
CC -!- SUBUNIT: Heterotrimer of UreA (gamma), UreB (beta) and UreC (alpha)
CC subunits. Three heterotrimers associate to form the active enzyme.
CC {ECO:0000256|HAMAP-Rule:MF_01954}.
CC -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000256|HAMAP-Rule:MF_01954}.
CC -!- SIMILARITY: Belongs to the urease beta subunit family.
CC {ECO:0000256|HAMAP-Rule:MF_01954}.
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DR EMBL; FPKU01000001; SFZ82971.1; -; Genomic_DNA.
DR RefSeq; WP_072340146.1; NZ_FPKU01000001.1.
DR AlphaFoldDB; A0A1K2HWF7; -.
DR STRING; 665118.SAMN02983003_1383; -.
DR OrthoDB; 9797217at2; -.
DR UniPathway; UPA00258; UER00370.
DR Proteomes; UP000183447; Unassembled WGS sequence.
DR GO; GO:0035550; C:urease complex; IEA:InterPro.
DR GO; GO:0009039; F:urease activity; IEA:UniProtKB-UniRule.
DR GO; GO:0043419; P:urea catabolic process; IEA:UniProtKB-UniRule.
DR CDD; cd00407; Urease_beta; 1.
DR FunFam; 2.10.150.10:FF:000001; Urease subunit beta; 1.
DR Gene3D; 2.10.150.10; Urease, beta subunit; 1.
DR HAMAP; MF_01954; Urease_beta; 1.
DR InterPro; IPR002019; Urease_beta-like.
DR InterPro; IPR036461; Urease_betasu_sf.
DR InterPro; IPR050069; Urease_subunit.
DR NCBIfam; NF009682; PRK13203.1; 1.
DR NCBIfam; TIGR00192; urease_beta; 1.
DR PANTHER; PTHR33569; UREASE; 1.
DR PANTHER; PTHR33569:SF1; UREASE; 1.
DR Pfam; PF00699; Urease_beta; 1.
DR SUPFAM; SSF51278; Urease, beta-subunit; 1.
PE 3: Inferred from homology;
KW Cytoplasm {ECO:0000256|HAMAP-Rule:MF_01954};
KW Hydrolase {ECO:0000256|ARBA:ARBA00022801, ECO:0000256|HAMAP-Rule:MF_01954};
KW Reference proteome {ECO:0000313|Proteomes:UP000183447}.
SQ SEQUENCE 101 AA; 10974 MW; 00D5228F0B709179 CRC64;
MIPGEIIPMA GDIELNAGAE QITIEVANTG DRPIQVGSHY HFYETNAGLR FDREKARGMR
LDIAAGTAVR FEPGQAREVR LVPLSGDRIV HGFQGKVMGA L
//
