ID A0A1L8TNV4_9ENTE Unreviewed; 904 AA.
AC A0A1L8TNV4;
DT 15-MAR-2017, integrated into UniProtKB/TrEMBL.
DT 15-MAR-2017, sequence version 1.
DT 08-OCT-2025, entry version 28.
DE RecName: Full=DNA translocase FtsK {ECO:0000256|ARBA:ARBA00020887};
GN ORFNames=RV04_GL001706 {ECO:0000313|EMBL:OJG45940.1};
OS Enterococcus hermanniensis.
OC Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
OC Enterococcus.
OX NCBI_TaxID=249189 {ECO:0000313|EMBL:OJG45940.1, ECO:0000313|Proteomes:UP000182077};
RN [1] {ECO:0000313|EMBL:OJG45940.1, ECO:0000313|Proteomes:UP000182077}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=DSM 17122 {ECO:0000313|EMBL:OJG45940.1,
RC ECO:0000313|Proteomes:UP000182077};
RA Zhong Z., Sun Z., Liu W., Zhang W., Zhang H.;
RT "Draft genome sequences of 29 type strains of Enterococci.";
RL Submitted (DEC-2014) to the EMBL/GenBank/DDBJ databases.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:OJG45940.1}.
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DR EMBL; JXKQ01000004; OJG45940.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A1L8TNV4; -.
DR STRING; 249189.RV04_GL001706; -.
DR Proteomes; UP000182077; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:InterPro.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR GO; GO:0016301; F:kinase activity; IEA:UniProtKB-KW.
DR GO; GO:0009401; P:phosphoenolpyruvate-dependent sugar phosphotransferase system; IEA:InterPro.
DR GO; GO:0006355; P:regulation of DNA-templated transcription; IEA:InterPro.
DR CDD; cd00009; AAA; 1.
DR CDD; cd00006; PTS_IIA_man; 1.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 1.
DR Gene3D; 3.40.50.510; Phosphotransferase system, mannose-type IIA component; 1.
DR Gene3D; 1.10.1790.10; PRD domain; 2.
DR Gene3D; 1.10.10.10; Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain; 1.
DR InterPro; IPR003593; AAA+_ATPase.
DR InterPro; IPR027417; P-loop_NTPase.
DR InterPro; IPR011608; PRD.
DR InterPro; IPR036634; PRD_sf.
DR InterPro; IPR004701; PTS_EIIA_man-typ.
DR InterPro; IPR036662; PTS_EIIA_man-typ_sf.
DR InterPro; IPR033887; PTS_IIA_man.
DR InterPro; IPR002078; Sigma_54_int.
DR InterPro; IPR025943; Sigma_54_int_dom_ATP-bd_2.
DR InterPro; IPR002831; Tscrpt_reg_TrmB_N.
DR InterPro; IPR036388; WH-like_DNA-bd_sf.
DR InterPro; IPR036390; WH_DNA-bd_sf.
DR PANTHER; PTHR32071:SF38; PSP OPERON TRANSCRIPTIONAL ACTIVATOR; 1.
DR PANTHER; PTHR32071; TRANSCRIPTIONAL REGULATORY PROTEIN; 1.
DR Pfam; PF03610; EIIA-man; 1.
DR Pfam; PF00874; PRD; 2.
DR Pfam; PF00158; Sigma54_activat; 1.
DR Pfam; PF01978; TrmB; 1.
DR SMART; SM00382; AAA; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR SUPFAM; SSF53062; PTS system fructose IIA component-like; 1.
DR SUPFAM; SSF63520; PTS-regulatory domain, PRD; 2.
DR SUPFAM; SSF46785; Winged helix' DNA-binding domain; 1.
DR PROSITE; PS51372; PRD_2; 2.
DR PROSITE; PS51096; PTS_EIIA_TYPE_4; 1.
DR PROSITE; PS00676; SIGMA54_INTERACT_2; 1.
DR PROSITE; PS50045; SIGMA54_INTERACT_4; 1.
PE 4: Predicted;
KW ATP-binding {ECO:0000256|ARBA:ARBA00022840};
KW DNA-binding {ECO:0000256|ARBA:ARBA00023125};
KW Kinase {ECO:0000256|ARBA:ARBA00022777};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741};
KW Reference proteome {ECO:0000313|Proteomes:UP000182077};
KW Transferase {ECO:0000256|ARBA:ARBA00022679}.
FT DOMAIN 86..318
FT /note="Sigma-54 factor interaction"
FT /evidence="ECO:0000259|PROSITE:PS50045"
FT DOMAIN 439..544
FT /note="PRD"
FT /evidence="ECO:0000259|PROSITE:PS51372"
FT DOMAIN 548..673
FT /note="PTS EIIA type-4"
FT /evidence="ECO:0000259|PROSITE:PS51096"
FT DOMAIN 792..902
FT /note="PRD"
FT /evidence="ECO:0000259|PROSITE:PS51372"
SQ SEQUENCE 904 AA; 103916 MW; 472FB0F69478D48B CRC64;
MKTVYVFSGG IVVKSRKDEV LEILKTNPNE QTAQTLVDQL NVDRTNISRY LNELTKEGLV
KKIDGRPVKF QIASVTAETH INFDNLIGRE ESLKSQIQKS KAAILYPPRG LHTIIFGETG
TGKTMFAECM YRFAVSANVL DETAPFITFN CADYAQNPQL LYGHIFGVKR GAFTGAEENR
EGLMEKADGG ILFLDEIHRL PPEGQEMLFT FIDKGTFRSL GDGKEKHASV QIIGATTETS
STFLSTFNRR IPMQIELPSL EERSLDERLA IIKEFLQQEA NRLMQEIAID KRSLLAFLLY
QAEGNIGQLK RDLKLVCAKA FLHHQTSNDS EKLMIIEDDL PLVVQKGLLR MNDVQDAMLP
FMDKRNLYLT LKPGTEEVVW GQDPNKDMEV YHSITYKLEK LGRENLSEID LEELISDDVD
QYFENYVEEL SHTNAYREII SDELWKLVNE LYDFAANRMK RDYDEKVRFA FALHINSTIE
RIRGNQFISH PNLNDIRRNY SKEFQIAIEF SNRIEEAYNI MIPLDEIGFI TMFLTMDNHE
KQKIDERQVA VLVVMHGKST ASSMLETVQE LLGTTKGFAF NMPLTVGTET MYSQIKNYVQ
QKREEFSEGI ILMTDMGSPN NFGNLIFHEM GIRTRVISMA STMLVLESLR LATLGRSLEE
IYTSVMTMFQ TMVRLEEPTK KDEKKVIIVA CFTGEGVSKR LNEVVSQIVN LDEYEVIQMQ
SLEREGFKHR IDQLVTHKDI VAIIGTMEIH YQKIPFIPAM DLFKRDKILE FQDLIGSTIT
LPEMVDSLTN DFTPELDVKT LFLMIDDVLK LLRRDNELII ENTAIQALSI HIAFLVDKVK
KEEERPLFDD VKYFHQENIL FFNQVASKLS LIENQFSVRF TEDDIAYIVK MLVDNQVKFG
LHTV
//
