ID A0A1M4TBK1_9BACT Unreviewed; 354 AA.
AC A0A1M4TBK1;
DT 15-MAR-2017, integrated into UniProtKB/TrEMBL.
DT 15-MAR-2017, sequence version 1.
DT 28-JAN-2026, entry version 26.
DE RecName: Full=DNA polymerase III subunit delta {ECO:0000256|ARBA:ARBA00017703};
DE EC=2.7.7.7 {ECO:0000256|ARBA:ARBA00012417};
GN ORFNames=SAMN05443144_101258 {ECO:0000313|EMBL:SHE41929.1};
OS Fodinibius roseus.
OC Bacteria; Pseudomonadati; Balneolota; Balneolia; Balneolales; Balneolaceae;
OC Fodinibius.
OX NCBI_TaxID=1194090 {ECO:0000313|EMBL:SHE41929.1, ECO:0000313|Proteomes:UP000184041};
RN [1] {ECO:0000313|EMBL:SHE41929.1, ECO:0000313|Proteomes:UP000184041}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=DSM 21986 {ECO:0000313|EMBL:SHE41929.1,
RC ECO:0000313|Proteomes:UP000184041};
RA Jaros S., Januszkiewicz K., Wedrychowicz H.;
RL Submitted (NOV-2016) to the EMBL/GenBank/DDBJ databases.
CC -!- CATALYTIC ACTIVITY:
CC Reaction=DNA(n) + a 2'-deoxyribonucleoside 5'-triphosphate = DNA(n+1) +
CC diphosphate; Xref=Rhea:RHEA:22508, Rhea:RHEA-COMP:17339, Rhea:RHEA-
CC COMP:17340, ChEBI:CHEBI:33019, ChEBI:CHEBI:61560, ChEBI:CHEBI:173112;
CC EC=2.7.7.7; Evidence={ECO:0000256|ARBA:ARBA00049244};
CC -!- SIMILARITY: Belongs to the DNA polymerase HolA subunit family.
CC {ECO:0000256|ARBA:ARBA00034754}.
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DR EMBL; FQUS01000001; SHE41929.1; -; Genomic_DNA.
DR RefSeq; WP_073058993.1; NZ_FQUS01000001.1.
DR AlphaFoldDB; A0A1M4TBK1; -.
DR STRING; 1194090.SAMN05443144_101258; -.
DR OrthoDB; 1172326at2; -.
DR Proteomes; UP000184041; Unassembled WGS sequence.
DR GO; GO:0009360; C:DNA polymerase III complex; IEA:InterPro.
DR GO; GO:0003677; F:DNA binding; IEA:InterPro.
DR GO; GO:0003887; F:DNA-directed DNA polymerase activity; IEA:UniProtKB-KW.
DR GO; GO:0006261; P:DNA-templated DNA replication; IEA:TreeGrafter.
DR Gene3D; 1.10.8.60; -; 1.
DR Gene3D; 1.20.272.10; -; 1.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 1.
DR InterPro; IPR008921; DNA_pol3_clamp-load_cplx_C.
DR InterPro; IPR048466; DNA_pol3_delta-like_C.
DR InterPro; IPR010372; DNA_pol3_delta_N.
DR InterPro; IPR005790; DNA_polIII_delta.
DR InterPro; IPR027417; P-loop_NTPase.
DR NCBIfam; TIGR01128; holA; 1.
DR PANTHER; PTHR34388; DNA POLYMERASE III SUBUNIT DELTA; 1.
DR PANTHER; PTHR34388:SF1; DNA POLYMERASE III SUBUNIT DELTA; 1.
DR Pfam; PF06144; DNA_pol3_delta; 1.
DR Pfam; PF21694; DNA_pol3_delta_C; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR SUPFAM; SSF48019; post-AAA+ oligomerization domain-like; 1.
PE 3: Inferred from homology;
KW DNA replication {ECO:0000256|ARBA:ARBA00022705};
KW DNA-directed DNA polymerase {ECO:0000256|ARBA:ARBA00022932};
KW Nucleotidyltransferase {ECO:0000256|ARBA:ARBA00022695};
KW Reference proteome {ECO:0000313|Proteomes:UP000184041};
KW Transferase {ECO:0000256|ARBA:ARBA00022679}.
FT DOMAIN 26..144
FT /note="DNA polymerase III delta N-terminal"
FT /evidence="ECO:0000259|Pfam:PF06144"
FT DOMAIN 227..349
FT /note="DNA polymerase III delta subunit-like C-terminal"
FT /evidence="ECO:0000259|Pfam:PF21694"
SQ SEQUENCE 354 AA; 40605 MW; 368A736BB060244A CRC64;
MAKKTSIERY SEILKELKSG ERKPVYFFHG EEEFFLDKLQ EAVETLVPED QKDFNFDLLY
GRDITVEKLL SIIRSFPMMA DRRVVILRDF KQLGDYAEIS GGDGGDVNEL IPYLKQPNPS
TLLVCIDAKK PSGNTKVGKA LKTSKHTGVH EFKEVPDYRL PDWIITWARS EYEKQIEPPA
AQMLAQYVGN SLQLLSTEID KVCTFVDTSE IIQESDIKKI IGFYREYSVF ELKDALISRN
LDKSLFIAEQ MLQHSKSNTG EIIRSVGFFY NLFSNIWQIK RLSAQGNTKK QVQNTLGISS
SWYFNKLWKD ASAFELAEMS RIFETLLDAD RAAKGFSTMD PATILLLMIK RIIN
//
