ID A0A1M5XC71_9VIBR Unreviewed; 276 AA.
AC A0A1M5XC71;
DT 15-MAR-2017, integrated into UniProtKB/TrEMBL.
DT 15-MAR-2017, sequence version 1.
DT 28-JAN-2026, entry version 28.
DE RecName: Full=hydroxymethylpyrimidine kinase {ECO:0000256|ARBA:ARBA00012135};
DE EC=2.7.1.49 {ECO:0000256|ARBA:ARBA00012135};
GN Name=thiD {ECO:0000313|EMBL:SHH97124.1};
GN ORFNames=VA7868_01077 {ECO:0000313|EMBL:SHH97124.1};
OS Vibrio aerogenes CECT 7868.
OC Bacteria; Pseudomonadati; Pseudomonadota; Gammaproteobacteria; Vibrionales;
OC Vibrionaceae; Vibrio.
OX NCBI_TaxID=1216006 {ECO:0000313|EMBL:SHH97124.1, ECO:0000313|Proteomes:UP000184608};
RN [1] {ECO:0000313|EMBL:SHH97124.1, ECO:0000313|Proteomes:UP000184608}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=CECT 7868 {ECO:0000313|EMBL:SHH97124.1,
RC ECO:0000313|Proteomes:UP000184608};
RA Jaros S., Januszkiewicz K., Wedrychowicz H.;
RL Submitted (NOV-2016) to the EMBL/GenBank/DDBJ databases.
CC -!- PATHWAY: Cofactor biosynthesis; thiamine diphosphate biosynthesis.
CC {ECO:0000256|ARBA:ARBA00004948}.
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DR EMBL; FQXZ01000011; SHH97124.1; -; Genomic_DNA.
DR RefSeq; WP_073602843.1; NZ_FQXZ01000011.1.
DR AlphaFoldDB; A0A1M5XC71; -.
DR STRING; 1216006.VA7868_01077; -.
DR OrthoDB; 9810880at2; -.
DR UniPathway; UPA00060; UER00138.
DR Proteomes; UP000184608; Unassembled WGS sequence.
DR GO; GO:0005829; C:cytosol; IEA:TreeGrafter.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR GO; GO:0008902; F:hydroxymethylpyrimidine kinase activity; IEA:UniProtKB-EC.
DR GO; GO:0008972; F:phosphomethylpyrimidine kinase activity; IEA:InterPro.
DR GO; GO:0009228; P:thiamine biosynthetic process; IEA:InterPro.
DR GO; GO:0009229; P:thiamine diphosphate biosynthetic process; IEA:UniProtKB-UniPathway.
DR CDD; cd01169; HMPP_kinase; 1.
DR FunFam; 3.40.1190.20:FF:000003; Phosphomethylpyrimidine kinase ThiD; 1.
DR Gene3D; 3.40.1190.20; -; 1.
DR InterPro; IPR004399; HMP/HMP-P_kinase_dom.
DR InterPro; IPR013749; PM/HMP-P_kinase-1.
DR InterPro; IPR029056; Ribokinase-like.
DR NCBIfam; TIGR00097; HMP-P_kinase; 1.
DR PANTHER; PTHR20858:SF17; HYDROXYMETHYLPYRIMIDINE_PHOSPHOMETHYLPYRIMIDINE KINASE THI20-RELATED; 1.
DR PANTHER; PTHR20858; PHOSPHOMETHYLPYRIMIDINE KINASE; 1.
DR Pfam; PF08543; Phos_pyr_kin; 1.
DR SUPFAM; SSF53613; Ribokinase-like; 1.
PE 4: Predicted;
KW ATP-binding {ECO:0000256|ARBA:ARBA00022840};
KW Kinase {ECO:0000256|ARBA:ARBA00022777, ECO:0000313|EMBL:SHH97124.1};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741};
KW Reference proteome {ECO:0000313|Proteomes:UP000184608};
KW Transferase {ECO:0000256|ARBA:ARBA00022679, ECO:0000313|EMBL:SHH97124.1}.
FT DOMAIN 19..267
FT /note="Pyridoxamine kinase/Phosphomethylpyrimidine kinase"
FT /evidence="ECO:0000259|Pfam:PF08543"
SQ SEQUENCE 276 AA; 29003 MW; 2254D0BF49E60791 CRC64;
MTVTQTNHPP IVLTIAGSDS SGGAGIQADI KTISATGSYA CSVITALTAQ NTCGVSGVSP
VPPEFIAQQL DAVFSDLNII AVKTGMLADA AVIRTVAAKL KQYRPPYLVI DPVMVATSGD
PLLAQNAVTT LKQELLPLAD VITPNLPEAA ALLQTQQPKN LHEMNALAGK LRTLGAGAVL
LKGGHLTKDN ESSDLLILPE ESRLLSGVRV QTRNTHGTGC TLSSAIASYL AQGDSLPEAV
RRAKRYISKA LQHADELKTG RGHGPVHHFF AGHWEI
//
