ID A0A1S1NEQ1_9MYCO Unreviewed; 267 AA.
AC A0A1S1NEQ1;
DT 12-APR-2017, integrated into UniProtKB/TrEMBL.
DT 12-APR-2017, sequence version 1.
DT 18-JUN-2025, entry version 21.
DE SubName: Full=2-dehydropantoate 2-reductase {ECO:0000313|EMBL:OHV04111.1};
GN ORFNames=BKN37_11705 {ECO:0000313|EMBL:OHV04111.1};
OS Mycobacterium talmoniae.
OC Bacteria; Bacillati; Actinomycetota; Actinomycetes; Mycobacteriales;
OC Mycobacteriaceae; Mycobacterium.
OX NCBI_TaxID=1858794 {ECO:0000313|EMBL:OHV04111.1, ECO:0000313|Proteomes:UP000179734};
RN [1] {ECO:0000313|EMBL:OHV04111.1, ECO:0000313|Proteomes:UP000179734}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=NE-TNMC-100812 {ECO:0000313|Proteomes:UP000179734};
RA Greninger A.L., Elliott B., Vasireddy S., Vasireddy R.;
RT "Genome sequence of Mycobacterium talmonii.";
RL Submitted (OCT-2016) to the EMBL/GenBank/DDBJ databases.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:OHV04111.1}.
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DR EMBL; MLQM01000051; OHV04111.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A1S1NEQ1; -.
DR Proteomes; UP000179734; Unassembled WGS sequence.
DR GO; GO:0005737; C:cytoplasm; IEA:TreeGrafter.
DR Gene3D; 1.10.1040.10; N-(1-d-carboxylethyl)-l-norvaline Dehydrogenase, domain 2; 1.
DR Gene3D; 3.40.50.720; NAD(P)-binding Rossmann-like Domain; 1.
DR InterPro; IPR008927; 6-PGluconate_DH-like_C_sf.
DR InterPro; IPR013328; 6PGD_dom2.
DR InterPro; IPR013752; KPA_reductase.
DR InterPro; IPR051402; KPR-Related.
DR InterPro; IPR013332; KPR_N.
DR NCBIfam; NF005091; PRK06522.2-2; 1.
DR NCBIfam; NF009541; PRK12921.1-1; 1.
DR PANTHER; PTHR21708:SF26; 2-DEHYDROPANTOATE 2-REDUCTASE; 1.
DR PANTHER; PTHR21708; PROBABLE 2-DEHYDROPANTOATE 2-REDUCTASE; 1.
DR Pfam; PF02558; ApbA; 1.
DR Pfam; PF08546; ApbA_C; 1.
DR SUPFAM; SSF48179; 6-phosphogluconate dehydrogenase C-terminal domain-like; 1.
PE 4: Predicted;
KW Reference proteome {ECO:0000313|Proteomes:UP000179734}.
FT DOMAIN 21..116
FT /note="Ketopantoate reductase N-terminal"
FT /evidence="ECO:0000259|Pfam:PF02558"
FT DOMAIN 141..260
FT /note="Ketopantoate reductase C-terminal"
FT /evidence="ECO:0000259|Pfam:PF08546"
SQ SEQUENCE 267 AA; 28084 MW; EF3460965DD862B6 CRC64;
MLCGHTPRAQ IELRPDDADP IIVPGPVHID PGQVTGPVGL VILAVKTTQI DAAAGWLAKL
CDADTVVCVM QNGVEQVERV APHCPTSTVL PGIIWFGAET QPDGWVRLRG TPRLALPVGP
AAESVAAPLR DAGCTVDLDP DFTTAAWRKL LVNAVAGLMV LSGRRAGMFR RDDVAALARA
YAGECVAVAR AEGARLGDEV IEDVVGLFAR GPADMGTSML ADREAHRALE WEVRNAVITV
RARRHGLPTP IGDVLVPLLA ADSDGPG
//
