ID A0A1S3PBN8_SALSA Unreviewed; 1740 AA.
AC A0A1S3PBN8;
DT 12-APR-2017, integrated into UniProtKB/TrEMBL.
DT 08-OCT-2025, sequence version 2.
DT 28-JAN-2026, entry version 44.
DE SubName: Full=Laminin subunit alpha-3 {ECO:0000313|RefSeq:XP_014025050.2};
GN Name=lama3 {ECO:0000313|RefSeq:XP_014025050.2};
OS Salmo salar (Atlantic salmon).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Actinopterygii; Neopterygii; Teleostei; Protacanthopterygii; Salmoniformes;
OC Salmonidae; Salmoninae; Salmo.
OX NCBI_TaxID=8030 {ECO:0000313|Proteomes:UP001652741, ECO:0000313|RefSeq:XP_014025050.2};
RN [1] {ECO:0000313|RefSeq:XP_014025050.2}
RP IDENTIFICATION.
RG RefSeq;
RL Submitted (AUG-2025) to UniProtKB.
CC -!- CAUTION: Lacks conserved residue(s) required for the propagation of
CC feature annotation. {ECO:0000256|PROSITE-ProRule:PRU00460}.
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DR RefSeq; XP_014025050.2; XM_014169575.2.
DR STRING; 8030.ENSSSAP00000042730; -.
DR PaxDb; 8030-ENSSSAP00000042730; -.
DR GeneID; 106584357; -.
DR KEGG; sasa:106584357; -.
DR Proteomes; UP001652741; Chromosome ssa23.
DR GO; GO:0005604; C:basement membrane; IEA:UniProtKB-ARBA.
DR GO; GO:0005576; C:extracellular region; IEA:UniProtKB-ARBA.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0004435; F:phosphatidylinositol-4,5-bisphosphate phospholipase C activity; IEA:InterPro.
DR GO; GO:0005102; F:signaling receptor binding; IEA:InterPro.
DR GO; GO:0007155; P:cell adhesion; IEA:UniProtKB-KW.
DR GO; GO:0035556; P:intracellular signal transduction; IEA:InterPro.
DR GO; GO:0006629; P:lipid metabolic process; IEA:InterPro.
DR GO; GO:0030155; P:regulation of cell adhesion; IEA:InterPro.
DR GO; GO:0030334; P:regulation of cell migration; IEA:InterPro.
DR GO; GO:0045995; P:regulation of embryonic development; IEA:InterPro.
DR CDD; cd00055; EGF_Lam; 1.
DR CDD; cd00110; LamG; 4.
DR Gene3D; 2.60.120.200; -; 5.
DR Gene3D; 2.10.25.10; Laminin; 2.
DR InterPro; IPR013320; ConA-like_dom_sf.
DR InterPro; IPR000742; EGF.
DR InterPro; IPR009254; Laminin_aI.
DR InterPro; IPR010307; Laminin_dom_II.
DR InterPro; IPR001791; Laminin_G.
DR InterPro; IPR002049; LE_dom.
DR InterPro; IPR050372; Neurexin-related_CASP.
DR InterPro; IPR001711; PLipase_C_Pinositol-sp_Y.
DR PANTHER; PTHR15036:SF67; LAMININ SUBUNIT ALPHA-LIKE PROTEIN; 1.
DR PANTHER; PTHR15036; PIKACHURIN-LIKE PROTEIN; 1.
DR Pfam; PF00053; EGF_laminin; 2.
DR Pfam; PF02210; Laminin_G_2; 4.
DR Pfam; PF06008; Laminin_I; 1.
DR Pfam; PF06009; Laminin_II; 1.
DR SMART; SM00180; EGF_Lam; 2.
DR SMART; SM00282; LamG; 5.
DR SUPFAM; SSF49899; Concanavalin A-like lectins/glucanases; 5.
DR SUPFAM; SSF57196; EGF/Laminin; 2.
DR PROSITE; PS00022; EGF_1; 1.
DR PROSITE; PS01248; EGF_LAM_1; 1.
DR PROSITE; PS50027; EGF_LAM_2; 2.
DR PROSITE; PS50025; LAM_G_DOMAIN; 4.
DR PROSITE; PS50008; PIPLC_Y_DOMAIN; 1.
PE 4: Predicted;
KW Cell adhesion {ECO:0000256|ARBA:ARBA00022889};
KW Coiled coil {ECO:0000256|ARBA:ARBA00023054};
KW Disulfide bond {ECO:0000256|ARBA:ARBA00023157, ECO:0000256|PROSITE-
KW ProRule:PRU00460};
KW Laminin EGF-like domain {ECO:0000256|PROSITE-ProRule:PRU00460};
KW Reference proteome {ECO:0000313|Proteomes:UP001652741};
KW Signal {ECO:0000256|SAM:SignalP}.
FT SIGNAL 1..30
FT /evidence="ECO:0000256|SAM:SignalP"
FT CHAIN 31..1740
FT /evidence="ECO:0000256|SAM:SignalP"
FT /id="PRO_5045664830"
FT DOMAIN 103..149
FT /note="Laminin EGF-like"
FT /evidence="ECO:0000259|PROSITE:PS50027"
FT DOMAIN 150..204
FT /note="Laminin EGF-like"
FT /evidence="ECO:0000259|PROSITE:PS50027"
FT DOMAIN 1019..1182
FT /note="Laminin G"
FT /evidence="ECO:0000259|PROSITE:PS50025"
FT DOMAIN 1189..1346
FT /note="Laminin G"
FT /evidence="ECO:0000259|PROSITE:PS50025"
FT DOMAIN 1199..1248
FT /note="PI-PLC Y-box"
FT /evidence="ECO:0000259|PROSITE:PS50008"
FT DOMAIN 1388..1558
FT /note="Laminin G"
FT /evidence="ECO:0000259|PROSITE:PS50025"
FT DOMAIN 1564..1737
FT /note="Laminin G"
FT /evidence="ECO:0000259|PROSITE:PS50025"
FT REGION 652..672
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 652..662
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT DISULFID 122..131
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00460"
FT DISULFID 175..184
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00460"
SQ SEQUENCE 1740 AA; 192813 MW; 9C9C4FBDF9C2FE59 CRC64;
MKMTQGTVCW FGGVWGLLLW CALFGPCTDG QSAPQRHPNG RYDYLSQNHQ SGKDPWHKGH
PRIPRKYCDT SFNNQSAGAI TQRCGTGYYR ERTGPHRGQC VPCNCNSLSN ECDEQTGRCL
NCQYNTDGDR CERCKEGYYG NAAQKTCRGC PCPFRANNFA VACLDIGANE IECLCKPGYT
GTRCERCAPD YYGNPMIYGG RCQRCHCDAT STCDHLTGKC KKPDDPGTND QCIECDSCTQ
ALLNDLENMD DGLELLRQQL QGIAYNSSPA NLNQLEGAIN ETKALVGRYS TIVDAQGPKV
NLLEAEVMSL DQDISLLEDK ASYTLSDAEN VLVKVIQTKQ RAEDFIPKAQ DLLMNIEDLL
RQLSEANSSV NNITVGVEEV ARMMKVVQRM VKEMRQLGCS NQTEKAAREQ EGAHKLLDFI
KNNMSAPLDD NQAVANETAQ SLMTSVSALS DLAVAVAEAD NTVNRTRSLN FNSTDFLRIL
TQLSGELERK RDSVLPEMNM TKDKLKNITG LLEMMKEMKK EYEHLAAEID GAKPNLTKRL
NDIAKAKQKE GIVVMAEEHA EELNRLAMEL QMAVHNATNS SDLQHASEST GAYSSIIKAI
EEAEMAANQS KEASDKALKD VEEQGLTNRS EELKHNASSL LTEALNAEKD LRETSAKVDN
HKQRVGQTKN KRKMLRKDAL AVTENLKEIQ RDDIGKLIDS AKATVNAANN TVNDVTDRLN
DISLAHIMLP NVSSNIGSVL DEVGNELKKL NETWPTLEDT LSRVKNLCSQ ASPSVSMTDS
IRRIKDVIEE ARDIVKRLSI GMTFNGKGHI ELRPPTNVED LKAFTAAELL LNLQETKPTR
GDRSRRRRQN TQDDRNLFVL YLGNKDSSKD FIGMAVKNNT LRCVYKLGGV IHELNTDHIT
RAKVNSTVFD KVVFNRVYQD AELSVTHRFP SQPVDVSKES NRPNTTVGLL NLDTNSVVFY
VGGYPDAFTP PVELRYPKYC GAIKLSTING QFFSLYNFKN AINVDKQSYI KVSVSLQSTV
PYYFDGTGYG LVTAIKEIKT PKRGVLKFHT NSQVENAILF YKGNEDSYTS VTVERGYVVV
QGRQGTQVLN AKSTRKVSLN NEQFVIVMDT TFKVHVTGVQ TEIIKIDNIM ESLKHFYIGG
LPASLRKRDN VTTPPFRGCI DNVILQSKEI EFNTTIGVSV GCPTSLLGVR EATFHPGGSL
SVDPQDFWTN PVAMVSLGFR TMENKGVLLR TSEERHGYQL SLVDGYVMFY FDENALKSTK
TYNDGRWHYL TALRNGTQLE LRVDNGDLGQ HQTTPQVKPN EQQVVLGGET FRGCLANLHI
RRPEESFIPA DFSSFTQKGD VILGMCRLQP PPQAIWEPAG LQERPKKSKP RSGAVHTECR
LPKVSDPQAY QLTGAASWLS YIIAPEELNF RPHFSLEIRT RSSAGLLLHV SGNGDISQVS
LYMTNGKIKL SLGKDRVIHN KNKSNDGRWH TVMVSVEKNT FHLVVDGFRV PDGILPAEEG
SSLALQNPVY LGSDPASKTS WAQGDSLPKK SVIGCIRHFK VYNVLVGEPA ANHGAPPCFD
GATEAGAYFA GTGHVVLDKF FTVGSRFELT FEARPRNTTG LLFHARGRHR NSLSVFMRKN
KVEVHVNDGL GDYSASVTPQ QNLCDGTFHV IAVSKQNNVV QLNVDSESQR TVGPSHSSYT
MTKDSLYIGG MSGTSKHKGV PISSSFVGCL RHIKVNKKPV VFKTASSVVG PVNINECPAD
//
