ID   A0A1S4KAK6_CULQU        Unreviewed;       441 AA.
AC   A0A1S4KAK6;
DT   12-APR-2017, integrated into UniProtKB/TrEMBL.
DT   12-APR-2017, sequence version 1.
DT   18-JUN-2025, entry version 24.
DE   RecName: Full=PLD phosphodiesterase domain-containing protein {ECO:0000259|PROSITE:PS50035};
OS   Culex quinquefasciatus (Southern house mosquito) (Culex pungens).
OC   Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota;
OC   Neoptera; Endopterygota; Diptera; Nematocera; Culicoidea; Culicidae;
OC   Culicinae; Culicini; Culex; Culex.
OX   NCBI_TaxID=7176 {ECO:0000313|EnsemblMetazoa:CPIJ017227-PA, ECO:0000313|Proteomes:UP000002320};
RN   [1] {ECO:0000313|EnsemblMetazoa:CPIJ017227-PA}
RP   IDENTIFICATION.
RC   STRAIN=JHB {ECO:0000313|EnsemblMetazoa:CPIJ017227-PA};
RG   EnsemblMetazoa;
RL   Submitted (MAY-2020) to UniProtKB.
CC   -!- SIMILARITY: Belongs to the phospholipase D family.
CC       {ECO:0000256|ARBA:ARBA00008664}.
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DR   AlphaFoldDB; A0A1S4KAK6; -.
DR   FunCoup; A0A1S4KAK6; 249.
DR   EnsemblMetazoa; CPIJ017227-RA; CPIJ017227-PA; CPIJ017227.
DR   VEuPathDB; VectorBase:CPIJ017227; -.
DR   VEuPathDB; VectorBase:CQUJHB007920; -.
DR   InParanoid; A0A1S4KAK6; -.
DR   OrthoDB; 1923775at2759; -.
DR   Proteomes; UP000002320; Unassembled WGS sequence.
DR   GO; GO:0003824; F:catalytic activity; IEA:InterPro.
DR   CDD; cd09106; PLDc_vPLD3_4_5_like_1; 1.
DR   CDD; cd09107; PLDc_vPLD3_4_5_like_2; 1.
DR   Gene3D; 3.30.870.10; Endonuclease Chain A; 2.
DR   InterPro; IPR050874; Diverse_PLD-related.
DR   InterPro; IPR032803; PLDc_3.
DR   InterPro; IPR001736; PLipase_D/transphosphatidylase.
DR   PANTHER; PTHR10185:SF17; GM01519P-RELATED; 1.
DR   PANTHER; PTHR10185; PHOSPHOLIPASE D - RELATED; 1.
DR   Pfam; PF00614; PLDc; 1.
DR   Pfam; PF13918; PLDc_3; 1.
DR   SMART; SM00155; PLDc; 2.
DR   SUPFAM; SSF56024; Phospholipase D/nuclease; 2.
DR   PROSITE; PS50035; PLD; 2.
PE   3: Inferred from homology;
KW   Reference proteome {ECO:0000313|Proteomes:UP000002320}.
FT   DOMAIN          157..184
FT                   /note="PLD phosphodiesterase"
FT                   /evidence="ECO:0000259|PROSITE:PS50035"
FT   DOMAIN          373..399
FT                   /note="PLD phosphodiesterase"
FT                   /evidence="ECO:0000259|PROSITE:PS50035"
SQ   SEQUENCE   441 AA;  50057 MW;  F38096AF8517A344 CRC64;
     MILLLIVMVV LLPLLDTNEK LADQRRKTAR SRNDVCLEGC RISLVESIPE GLVYPKGSPS
     FMSTYDAWKL LIKSAQQKIE IGSFYWSLRR EDVYNHSSAW QGEDIFKTLL ETGTSGNVSI
     KIAQSMPTSA NPSVDTEIFT KRNAADVRSV DFPRLFGGGV LHTKVWVIDR RHFYVGSANM
     DWRSLTQVKE LGVLAVNCSC LATDIAKIFD VYWDMGVPNA QLPDQWPAAY STKYNANNTL
     SVQFDDEYKV DTYLSSSPPP MSTRGRTHDV DAILDVIERA EKFIHISVMD YLPLTLYTPK
     TQFWPIIDDA LRRAAIDRKI SIRLLISLWA HSRSSEQRFL DSLQVISNSL PGVSIDIKRF
     IVPADDDQQK IPFARVNHNK YMVTDNTAYI GTSNWSGDYF IDTAGIGLVM SSYEGNRTIV
     NDLQDVFERD WNSDYAIRMD E
//