ID A0A1S8AV51_9EURY Unreviewed; 176 AA.
AC A0A1S8AV51;
DT 10-MAY-2017, integrated into UniProtKB/TrEMBL.
DT 10-MAY-2017, sequence version 1.
DT 18-JUN-2025, entry version 25.
DE SubName: Full=Cation:proton antiporter {ECO:0000313|EMBL:OLZ40467.1};
GN ORFNames=A6E15_05455 {ECO:0000313|EMBL:OLZ40467.1};
OS Natrinema saccharevitans.
OC Archaea; Methanobacteriati; Methanobacteriota; Stenosarchaea group;
OC Halobacteria; Halobacteriales; Natrialbaceae; Natrinema.
OX NCBI_TaxID=301967 {ECO:0000313|EMBL:OLZ40467.1, ECO:0000313|Proteomes:UP000189370};
RN [1] {ECO:0000313|Proteomes:UP000189370}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=AB14 {ECO:0000313|Proteomes:UP000189370};
RA Chen S.-C., Lai M.-C.;
RL Submitted (APR-2016) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBCELLULAR LOCATION: Cell membrane {ECO:0000256|ARBA:ARBA00004651};
CC Multi-pass membrane protein {ECO:0000256|ARBA:ARBA00004651}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:OLZ40467.1}.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; LWLN01000001; OLZ40467.1; -; Genomic_DNA.
DR RefSeq; WP_076144531.1; NZ_LWLN01000001.1.
DR AlphaFoldDB; A0A1S8AV51; -.
DR STRING; 301967.A6E15_05455; -.
DR OrthoDB; 19265at2157; -.
DR Proteomes; UP000189370; Unassembled WGS sequence.
DR GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR InterPro; IPR050622; CPA3_antiporter_subunitB.
DR InterPro; IPR007182; MnhB.
DR NCBIfam; NF009160; PRK12505.1; 1.
DR PANTHER; PTHR33932; NA(+)/H(+) ANTIPORTER SUBUNIT B; 1.
DR PANTHER; PTHR33932:SF4; NA(+)_H(+) ANTIPORTER SUBUNIT B; 1.
DR Pfam; PF04039; MnhB; 1.
PE 4: Predicted;
KW Cell membrane {ECO:0000256|ARBA:ARBA00022475};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000189370};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}.
FT TRANSMEM 12..31
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 43..62
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 74..96
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 123..146
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 14..135
FT /note="Na+/H+ antiporter MnhB subunit-related protein"
FT /evidence="ECO:0000259|Pfam:PF04039"
FT REGION 148..176
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 160..176
FT /note="Acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 176 AA; 18596 MW; 8E0831295C2273BA CRC64;
MADYDDTYTE SQVIMTAVKI IAPFTLTYGL FMTFHGGDAP GGGFQGGTIV GVTVLMLAFA
FGIEPTRQWL RNSFITGIVT GGVVIFGAIG FGMIALGGEF LEFYKLKEVF DIKPKWGLEA
VEIGGISLIV SGVIISLFFT MAAGFAPDRR SDTGGASGVD VDDAPDATEP EVSDDD
//
