ID A0A1S8B0D2_9EURY Unreviewed; 1616 AA.
AC A0A1S8B0D2;
DT 10-MAY-2017, integrated into UniProtKB/TrEMBL.
DT 10-MAY-2017, sequence version 1.
DT 18-JUN-2025, entry version 38.
DE RecName: Full=histidine kinase {ECO:0000256|ARBA:ARBA00012438};
DE EC=2.7.13.3 {ECO:0000256|ARBA:ARBA00012438};
GN ORFNames=A6E15_16645 {ECO:0000313|EMBL:OLZ42490.1};
OS Natrinema saccharevitans.
OC Archaea; Methanobacteriati; Methanobacteriota; Stenosarchaea group;
OC Halobacteria; Halobacteriales; Natrialbaceae; Natrinema.
OX NCBI_TaxID=301967 {ECO:0000313|EMBL:OLZ42490.1, ECO:0000313|Proteomes:UP000189370};
RN [1] {ECO:0000313|Proteomes:UP000189370}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=AB14 {ECO:0000313|Proteomes:UP000189370};
RA Chen S.-C., Lai M.-C.;
RL Submitted (APR-2016) to the EMBL/GenBank/DDBJ databases.
CC -!- CATALYTIC ACTIVITY:
CC Reaction=ATP + protein L-histidine = ADP + protein N-phospho-L-
CC histidine.; EC=2.7.13.3; Evidence={ECO:0000256|ARBA:ARBA00000085};
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:OLZ42490.1}.
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DR EMBL; LWLN01000001; OLZ42490.1; -; Genomic_DNA.
DR RefSeq; WP_076147951.1; NZ_LWLN01000001.1.
DR STRING; 301967.A6E15_16645; -.
DR OrthoDB; 342253at2157; -.
DR Proteomes; UP000189370; Unassembled WGS sequence.
DR GO; GO:0016301; F:kinase activity; IEA:UniProtKB-KW.
DR GO; GO:0006355; P:regulation of DNA-templated transcription; IEA:InterPro.
DR CDD; cd00130; PAS; 6.
DR Gene3D; 2.10.70.100; -; 1.
DR Gene3D; 3.30.450.40; -; 3.
DR Gene3D; 3.30.450.20; PAS domain; 6.
DR InterPro; IPR031803; BAT_GAF/HTH-assoc.
DR InterPro; IPR003018; GAF.
DR InterPro; IPR029016; GAF-like_dom_sf.
DR InterPro; IPR007050; HTH_bacterioopsin.
DR InterPro; IPR001610; PAC.
DR InterPro; IPR000014; PAS.
DR InterPro; IPR000700; PAS-assoc_C.
DR InterPro; IPR035965; PAS-like_dom_sf.
DR InterPro; IPR013656; PAS_4.
DR InterPro; IPR013767; PAS_fold.
DR InterPro; IPR013655; PAS_fold_3.
DR InterPro; IPR013324; RNA_pol_sigma_r3/r4-like.
DR InterPro; IPR052162; Sensor_kinase/Photoreceptor.
DR NCBIfam; TIGR00229; sensory_box; 6.
DR PANTHER; PTHR43304:SF1; PAC DOMAIN-CONTAINING PROTEIN; 1.
DR PANTHER; PTHR43304; PHYTOCHROME-LIKE PROTEIN CPH1; 1.
DR Pfam; PF15915; BAT; 1.
DR Pfam; PF13185; GAF_2; 2.
DR Pfam; PF04967; HTH_10; 1.
DR Pfam; PF00989; PAS; 2.
DR Pfam; PF08447; PAS_3; 2.
DR Pfam; PF08448; PAS_4; 2.
DR SMART; SM00065; GAF; 2.
DR SMART; SM00086; PAC; 6.
DR SMART; SM00091; PAS; 6.
DR SUPFAM; SSF55781; GAF domain-like; 3.
DR SUPFAM; SSF55785; PYP-like sensor domain (PAS domain); 6.
DR SUPFAM; SSF88659; Sigma3 and sigma4 domains of RNA polymerase sigma factors; 1.
DR PROSITE; PS50113; PAC; 6.
DR PROSITE; PS50112; PAS; 6.
PE 4: Predicted;
KW Coiled coil {ECO:0000256|SAM:Coils};
KW Kinase {ECO:0000256|ARBA:ARBA00022777, ECO:0000313|EMBL:OLZ42490.1};
KW Phosphoprotein {ECO:0000256|ARBA:ARBA00022553};
KW Reference proteome {ECO:0000313|Proteomes:UP000189370};
KW Transcription {ECO:0000256|ARBA:ARBA00023015};
KW Transcription regulation {ECO:0000256|ARBA:ARBA00023015};
KW Transferase {ECO:0000256|ARBA:ARBA00022679}.
FT DOMAIN 305..375
FT /note="PAS"
FT /evidence="ECO:0000259|PROSITE:PS50112"
FT DOMAIN 377..428
FT /note="PAC"
FT /evidence="ECO:0000259|PROSITE:PS50113"
FT DOMAIN 458..502
FT /note="PAS"
FT /evidence="ECO:0000259|PROSITE:PS50112"
FT DOMAIN 505..556
FT /note="PAC"
FT /evidence="ECO:0000259|PROSITE:PS50113"
FT DOMAIN 553..623
FT /note="PAS"
FT /evidence="ECO:0000259|PROSITE:PS50112"
FT DOMAIN 627..679
FT /note="PAC"
FT /evidence="ECO:0000259|PROSITE:PS50113"
FT DOMAIN 676..746
FT /note="PAS"
FT /evidence="ECO:0000259|PROSITE:PS50112"
FT DOMAIN 750..802
FT /note="PAC"
FT /evidence="ECO:0000259|PROSITE:PS50113"
FT DOMAIN 803..847
FT /note="PAS"
FT /evidence="ECO:0000259|PROSITE:PS50112"
FT DOMAIN 875..925
FT /note="PAC"
FT /evidence="ECO:0000259|PROSITE:PS50113"
FT DOMAIN 926..998
FT /note="PAS"
FT /evidence="ECO:0000259|PROSITE:PS50112"
FT DOMAIN 1001..1051
FT /note="PAC"
FT /evidence="ECO:0000259|PROSITE:PS50113"
FT REGION 81..103
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COILED 119..146
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 1201..1228
FT /evidence="ECO:0000256|SAM:Coils"
SQ SEQUENCE 1616 AA; 179367 MW; D5BBDBDB2EA5D829 CRC64;
MIAVAAPLES LAQRRGRLTV VVATLGVLVA LALGTTPAVS LPSVPFPGIV VFGLAARRGS
DRPTDIERLT DELRGFVSRL EDADPTADGG SLPTEPDLAD VGRDRDDEIG RLSAAVDELA
STVRDRERQR AESERYRREL ARITSDPEPG TETKIRRLLE LGCERLGLET GLVSHIDEPA
DRYEVETAVG TGADLEGAVL DLSETHCRNA VTSDDVVGIS ETPAADTEAG AAVESDVGCY
IGGKILVDGD LYGTVCFVGS EPRDRSFSPA ERSFVDLLAR WVSGAFERRE YVAAIEERER
RLERTQAFTD DMLDAVDDVV YLLEEDGDLR RWNETLVDVT GYSDAAVAEM NALDFFDAEN
EGAIRESMRD AFETGETRVE AELRTKSGER IPYEFIASVL EDPNGNPIEV GIGRDISDRR
ERERRLERTT SLLEQSQRLA DVGAWELDVS TEPYALQWTT EIRRILGVPP DEPIDLEASI
EFYHPEDRPR IREAIERAIA DGEPYDLELR ARTADDDLRW VRSIGEPVRE DGEIVTLRGS
FQDITDRKKR ERDLERAETV LQALDELVYT IDEDGEFTFL NDAIEGITGY EADDLIGENV
STVMDEADLE TARDRIRDLR SAGEPTRTFE MDLETVDGDV IDAENHMALL PSEDGEFAGT
AGVVRDITDR KERERDLERF EAIVQALDEL VYTLDDEGRF TYLNDAAKPI LGYEPAELLG
EPAATVIPSP DVERAQDRIR DLLRSDEPSQ TVEIVLETAD GEVIDVENHI ALLPGDDGEF
VGTAGVVRDI TARKERERRL ETTRARLEAL FENSPDMIDV LDPAGTIVDG NRRFYDELGY
DESDLLGTKI WDHDDRFDAD EVSALLAEMA VGERRRFEGR YRRRDDSTFP VEVHLIRLDI
VEDNRYLAIT RDITDRKERE RDLRETKRRL ELALEGTNTG VWEWDLDSDT VAWNETLERL
VGLDPGAFEG TFDAFRERLH PDDVGRIETM AQRAIENDTL FQTEFRLRHE DGSRIWVGAR
GRLVDDEAGQ RLVGINNDIT DRKERELALE SLHDAARNLL GTDTEAEVSA LVVETAVEVI
EASGAAVYRL DPAVNRLVPA ASTEAFDRLC NDAPSVPIGD GESALWNTYV TGTGTVVDDP
SSFDRSRLFG PAVESGVVVP IGDYGVFAVA TDAEPIDAEA RRLIETLVAT TEAAFDRLES
EASLREREAQ LERRNERLNR QIETTELIRR IDQVLIGAES RGEIERTVPE RLLEADSVAL
AWIGDRDPSG TRLEPRAWAG DGEAYLDDVS LADDAAEPAV RTAADGTPTV VSNVVEGLQN
DPWRRQAVDR GFQSVISVPL SHAEYSYGVL TVYADEPEAF GDLERTVLTE LGEGIANAIT
AMKTREALHA ERLLELTLRI DDDEDLLSRL AAKTGASIEY AGLGSHASDE TLLFVETDGV
APDDVRSALA DLVSVTDARL ISETDGTCRF EATVTGDPLA ARLVRHGGSP RSIRTDGEGL
EVVVDVPTGT DVREFVETLE EGRGAVELRA RRHVERSMGT RSELVTSLFD ALTDRQLEVL
RTAYFAGFFE WPRESTGEEI AEMLAVTQPT VNRHLRLAQG RLLAQLFEDR VPVAPS
//
