ID A0A1U7QL11_MESAU Unreviewed; 710 AA.
AC A0A1U7QL11;
DT 10-MAY-2017, integrated into UniProtKB/TrEMBL.
DT 10-MAY-2017, sequence version 1.
DT 28-JAN-2026, entry version 39.
DE RecName: Full=Zinc finger protein 750 {ECO:0000256|ARBA:ARBA00040216};
GN Name=Znf750 {ECO:0000313|RefSeq:XP_005069831.1};
OS Mesocricetus auratus (Golden hamster).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea;
OC Cricetidae; Cricetinae; Mesocricetus.
OX NCBI_TaxID=10036 {ECO:0000313|Proteomes:UP000886700, ECO:0000313|RefSeq:XP_005069831.1};
RN [1] {ECO:0000313|RefSeq:XP_005069831.1}
RP IDENTIFICATION.
RC TISSUE=Liver {ECO:0000313|RefSeq:XP_005069831.1};
RG RefSeq;
RL Submitted (AUG-2025) to UniProtKB.
CC -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000256|ARBA:ARBA00004123}.
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DR RefSeq; XP_005069831.1; XM_005069774.4.
DR AlphaFoldDB; A0A1U7QL11; -.
DR STRING; 10036.ENSMAUP00000025216; -.
DR GeneID; 101830773; -.
DR KEGG; maua:101830773; -.
DR CTD; 79755; -.
DR eggNOG; ENOG502QU7X; Eukaryota.
DR OrthoDB; 8933073at2759; -.
DR Proteomes; UP000886700; Unplaced.
DR GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR GO; GO:0001228; F:DNA-binding transcription activator activity, RNA polymerase II-specific; IEA:Ensembl.
DR GO; GO:0001227; F:DNA-binding transcription repressor activity, RNA polymerase II-specific; IEA:Ensembl.
DR GO; GO:1990841; F:promoter-specific chromatin binding; IEA:Ensembl.
DR GO; GO:0000978; F:RNA polymerase II cis-regulatory region sequence-specific DNA binding; IEA:Ensembl.
DR GO; GO:0008270; F:zinc ion binding; IEA:UniProtKB-KW.
DR GO; GO:0030154; P:cell differentiation; IEA:UniProtKB-KW.
DR GO; GO:0061436; P:establishment of skin barrier; IEA:Ensembl.
DR GO; GO:0044091; P:membrane biogenesis; IEA:Ensembl.
DR GO; GO:0010719; P:negative regulation of epithelial to mesenchymal transition; IEA:Ensembl.
DR GO; GO:2000304; P:positive regulation of ceramide biosynthetic process; IEA:Ensembl.
DR GO; GO:0010628; P:positive regulation of gene expression; IEA:Ensembl.
DR InterPro; IPR039363; ZNF750.
DR InterPro; IPR039064; ZNF750_Znf.
DR PANTHER; PTHR14678; PROLINE-RICH PROTEIN 35-RELATED; 1.
DR PANTHER; PTHR14678:SF1; ZINC FINGER PROTEIN 750; 1.
DR Pfam; PF15269; zf-C2H2_7; 1.
PE 4: Predicted;
KW Activator {ECO:0000256|ARBA:ARBA00023159};
KW Differentiation {ECO:0000256|ARBA:ARBA00022782};
KW Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW Nucleus {ECO:0000256|ARBA:ARBA00023242};
KW Reference proteome {ECO:0000313|Proteomes:UP000886700};
KW Transcription {ECO:0000256|ARBA:ARBA00023163};
KW Transcription regulation {ECO:0000256|ARBA:ARBA00023015};
KW Zinc {ECO:0000256|ARBA:ARBA00022833};
KW Zinc-finger {ECO:0000256|ARBA:ARBA00022771}.
FT DOMAIN 6..57
FT /note="Zinc finger protein 750-like zinc finger"
FT /evidence="ECO:0000259|Pfam:PF15269"
FT REGION 63..153
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 354..515
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 559..618
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 634..710
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 67..106
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 354..363
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 369..396
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 412..423
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 444..467
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 475..502
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 581..618
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 645..664
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 710 AA; 77400 MW; A2B9EA29A2383537 CRC64;
MSLLKERKPK KPHYIPRPPG KPFKYKCFQC PFTCNEKSHL FNHMKYGLCK NSITLVSEQD
RVPKCPKSTS LDPKQTHQPE PTSKPVTSKS LPNGLSSFDP KSQQGSAKEE AKENLEMQAR
GTHKGPQKTA LQKEVTSEAI LSTQPGLDSG ARSSAFVPVG EHRLRGPEDT EASEMLALTS
STTKATSFHA KSAFHTPGYP WKAGSPFLPP EFPHKIPSSK GFGAISPYMH PAIPEYPHPF
YTEHGLTAIY SPYLLTGNTP ECDTTLLSVY GSQDQRHFLS HPGPIPKHLN TTPSTYDHYR
FFQQYHSNLP IPYGFYRPES AFPSYSLRLP PVTGITRDQS SRLFEGAALA YPASSPSELN
LSNSHRKHME FEKESPVPEA KDPSKDGQRD AEEAKMSPRA GSAATGSPGR PSPTNFTQTS
QTFEGLCDLS NKAASSGTLE RLQQPEQSPT AFKPVQRSSE SPHSQPPANR AESPKSLQAM
NSDSPAQIET SSSLITEASP SSPEDHSRIA PLNLSKKLET NPAATYGPMY VDNAQADTLG
FSGLQDLPLN LSVKDSCNAW APRPVFPSPP QGAEPTAAPK TETKGSEGRT SHVETHQDKA
HSRKTPDVHT VDSSDEQKQT AAVALCQLAA YSPGNVRVGD DESTAQESTC QDVPTHSSTG
NQGAHSDLRP KGQKRTSQRD AGKSQQGTKK PKLNNAVPRV LTLRKRTRVS
//
